CAS: 39515-40-7; Cyphenothrin

该化合物是一种合成除虫菊酯,以其对各种害虫的效力而闻名于众,其特点是其高能和快速击倒效应,在农业和家庭虫害控制应用中成为普遍选择,青蒿素对哺乳动物和鸟类的毒性较低,在按照准则使用时有助于其有利的安全特征,该化合物通常是一种液体或气溶胶,并且通常与其他活性成分结合,以提高其功效,其作用方式涉及破坏昆虫的...

结构式图片

欧盟法规

ECHA物质ECHA物质C&L通报欧盟生物杀灭剂法规欧盟《生物杀灭剂法规》REACH预注册

合成工艺路线路线简述

    菊酰氯 反应生成 苯醚氰菊酯
    参考文献:Xiyama,Tamehdziro;Fudzita,Makoto
    标题:Xiyama,Tamehdziro;Fudzita,Makoto

    海关参考信息

    专利信息


    专利号:WO-2025056767-A1
    优先权日:2023-09-15
    标题 :Process for the preparation of enantiomerically enriched aliphatic amines
    发明人:BOU HAMDAN FARHAN; GODINEAU EDOUARD; SMEJKAL TOMAS; DUMEUNIER RAPHAEL; BOUSSEMGHOUNE MOHAMED ABDELOUAHAB; BLUM MATHIAS
    权利人:SYNGENTA CROP PROTECTION AG
    摘要:The present invention relates to a process for the preparation of enantiomerically enriched cyclobutylamines of formula (I) from α-tertiary cyclobutanones and reacting said enantiomerically enriched cyclobutylamines to enantiomerically enriched cyclobutylamides. Such compounds are useful intermediates in the synthesis of microbiocidal thiazole compounds.

    专利号:US-9487471-B1
    优先权日:2014-04-14
    标题 :Synthesis of pyrethroids and pyrethroid-containing compositions
    发明人:COELHO PEDRO; MEINHOLD PETER; CHEN MIKE M Y
    权利人:PROVIVI INC
    摘要:The present invention provides methods for synthesizing pyrethroid compounds. The methods include forming a first reaction comprising an olefin and an allethrolone-type unsaturated alcohol under conditions sufficient to form a metathesis product and converting the metathesis product to the pyrethroid. Methods of the invention can be used to prepare compounds including pyrethrin I, cinerin I, jasmolin I, pyrethrin II, cinerin II, and jasmolin II as well as other synthetic pyrethroid compounds. Insecticidal compositions and methods for controlling insects are also described.

    专利号:WO-2021074309-A1
    优先权日:2019-10-16
    标 题:1-(3-quinolyl)-3,4-dihydroisoquinoline derivatives as fungicides for combating specific phytopathogens
    发明人:WEISS MATTHIAS; QUARANTA LAURA; BOU HAMDAN FARHAN; MAHAJAN ATUL; WILLIAMS SIMON; KILARU JAGADEESH; SEN INDIRA; BIERI STEPHANE; DIGGELMANN MARTIN
    权利人:SYNGENTA CROP PROTECTION AG
    摘要:1-(3-quinolyl)-3,4-dihydroisoquinoline derivatives of formula (I) as well as a method of combating, preventing or controlling the phytopathogens Mycosphaerella graminicola (Septoria tritici), Fusarium culmorum, Gibberella zeae (Fusarium graminearum) and Monographella nivalis (Microdochium nivale), which comprises applying to the phytopathogen, to the locus of the phytopathogen, or to a plant susceptible to attack by the phytopathogen, or to propagation material thereof, a fungicidally effective amount of a 1-(3-quinolyl)-3,4-dihydroisoquinoline derivative of formula (I). The present description discloses the synthesis of exemplary compounds, formulation examples, relevant biological data (antifungal activity against Mycosphaerella graminicola (Septoria tritici), Fusarium culmorum, Gibberella zeae (Fusarium graminearum) and Monographella nivalis (Microdochium nivale) when spayed on plants), as well as comparative data against three prior art compounds (e.g. pages 52 to 85; formulation examples; examples A1 to A3; table E; compounds E.01 to E.187; biological examples). Exemplary compounds are e.g.: 5-bromo-1-(8-fluoro-3-quinolyl)spiro[4H-isoquinoline-3,1'- cyclopropane] (example A1) 5-bromo-1-(8-fluoro-3-quinolyl)-3,3-dimethyl-4H-isoquinoline (example A2) 1-(8-fluoro-3-quinolyl)-3,3-dimethyl-4H-isoquinoline-5-carbonitrile (example A3)

    专利号:WO-2021074311-A1
    优先权日:2019-10-16
    标题:1-(3-quinolyl)-1,2,3,4-tetrahydroisoquinoline derivatives as fungicides for combating specific phytopathogens
    发明人:WEISS MATTHIAS; QUARANTA LAURA; BOU HAMDAN FARHAN; MAHAJAN ATUL; WILLIAMS SIMON; KILARU JAGADEESH; BIERI STEPHANE; DIGGELMANN MARTIN
    权利人:SYNGENTA CROP PROTECTION AG
    摘要:1-(3-quinolyl)-1,2,3,4-tetrahydroisoquinoline derivatives of formula (I) as well as a method of combating, preventing or controlling the phytopathogens Mycosphaerella graminicola (Septoria tritici), Fusarium culmorum, Gibberella zeae (Fusarium graminearum) and Monographella nivalis (Microdochium nivale), which comprises applying to the phytopathogen, to the locus of the phytopathogen, or to a plant susceptible to attack by the phytopathogen, or to propagation material thereof, a fungicidally effective amount of a 1-(3-quinolyl)-1,2,3,4-tetrahydroisoquinoline derivatives of formula (I). The present description discloses the synthesis of exemplary compounds, formulation examples, relevant biological data (antifungal activity against Mycosphaerella graminicola, Monographella nivalis, Fusarium culmorum and/or Gibberella zeae when spayed on plants) (e.g. pages 47 to 55; examples A1 and A2; compounds E.01 to E.17; table E). An exemplary compounds is e.g.: 3-(5-bromo-3,3-dimethyl-2,4-dihydro-1 H-isoquinolin-1-yl)-8-fluoro- quinoline (example A1)

    专利号:US-2011230343-A1
    优先权日:2008-10-24
    标题 :Method for the Manufacture of Microparticles Comprising an Effect Substance
    发明人:SCHROERS MICHAEL; DYLLICK-BRENZINGER RAINER; MERK MICHAEL; BARG HEIKO
    权利人:BASF SE
    摘要:A subject matter of the present invention is a process for the preparation of effect compound-comprising microparticles M comprising A) the formation of a crude suspension of microparticles A by means of enzymatic polyester synthesis in an inverse miniemulsion comprising enzyme, effect compound and polyester monomers; and B) the polymerization of wall monomers from the group consisting of ethylenically unsaturated monomers, polyisocyanates and polyepoxides in the crude suspension of microparticles A. Furthermore, the present invention relates to microparticles M which can be obtained by means of the process according to the invention and also to an agrochemical formulation comprising microparticles M. In addition, the present invention relates to the use of microparticles M prepared according to the invention as component in colorants, cosmetics, drugs, biocides, plant protection agents, fertilizers, additives for food or animal fodder, or auxiliaries for polymers, paper, textiles, leather, detergents or cleaners. Finally, the invention also relates to a method for combating undesirable plant growth, to a method for combating undesirable insect or acarid infestation on plants and/or for combating phytopathogenic fungi, and to seeds treated with the agrochemical formulation.

    专利号:US-11213031-B2
    优先权日:2017-11-13
    标 题:Tetrazolylpropyl derivatives and their use as fungicides
    发明人:SUDAU ALEXANDER; HOFFMANN SEBASTIAN; DAHMEN PETER; WEBSTER ROBERT ALAN; MEISSNER RUTH; GOERTZ ANDREAS; MILLER RICARDA; COQUERON PIERRE-YVES; BERNIER DAVID; NICOLAS LIONEL; BRUNET STEPHANE; KENNEL PHILIPPE; TOQUIN VALERIE; GOURGUES MATHIEU; LOQUE DOMINIQUE; THOMAS VINCENT
    权利人:BAYER AG; BAYER CROPSCIENCE AG
    摘要:The present invention relates to tetrazolylpropyl derivatives of formula (I) n nwherein one of V 1 and V 2 represents CR 3 and the other one of V 1 and V 2 represents N, Q represents a 6-membered aromatic cycle as defined in the specification, and R 1 , R 2 , R 3 , R 4 , and R 5 are defined as disclosed in the specification, to compositions comprising such compounds, to the use of said compounds as fungicides, as well as to particular intermediates useful in the synthesis of said tetrazolylpropyl derivatives.
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    主要参考文献


    1: Driver JH, Ross JH, Holden LR, Selim S, Sharp JK, Carlson D, Nouvel L. Cyphenothrin Flea and Tick Squeeze-On for Dogs: Evaluation of Potential Health Risks Based on the Results of Observational Biological Monitoring. J Toxicol Environ Health A. 2015;78(17):1105-21. doi: 10.1080/15287394.2015.1050712. Epub 2015 Aug 20. doi: 10.1186/s13071-015-0992-1.
    3: Ren X, Chen L. Quantum dots coated with molecularly imprinted polymer as fluorescence probe for detection of cyphenothrin. Biosens Bioelectron. 2015 Feb 15;64:182-8. doi: 10.1016/j.bios.2014.08.086. Epub 2014 Sep 6. eCollection 2016.
    5: Erkmen B, Caliskan M, Yerli SV. Histopathological effects of cyphenothrin on the gills of Lebistes reticulatus. Vet Hum Toxicol. 2000 Feb;42(1):5-7. doi: 10.1021/jf803807b. doi: 10.1016/j.envres.2015.02.008. Epub 2015 Feb 16. doi: 10.5152/tpd.2012.21. doi: 10.1111/j.1948-7134.2009.00029.x. Russian. doi: 10.1016/j.jpba.2009.09.048. Epub 2009 Oct 7. doi: 10.1016/j.talanta.2014.07.098. Epub 2014 Aug 8. doi: 10.1016/j.chroma.2013.12.079. Epub 2014 Jan 2. Epub 2007 May 10.

    合成参考文献


    摘要:Farm Chemicals Handbook., -(C156), 1991
    摘要:California Environmental Protection Agency/Department of Pesticide Regulation; Summary of Toxicology Data, Cyphenothrin, Chemical Code No. 3885, p.7 (Revised Date: May 1, 1995). Available from, as of July 5, 2018:
    摘要:ATSDR Tox Profiles. Pyrethrins and Pyrethroids. Available from, as of July 17, 2018:
    摘要:United States Environmental Protection Agency/ Prevention, Pesticides and Toxic Substances; Status of Pesticides in Registration, Reregistration, and Special Review. (1998) EPA 738-R-98-002, p. 362
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