CAS: 402-13-1; 2-Amino-4-(Trifluoromethyl)Benzoic Acid

上下游产品

CAS号320-94-5 2-硝基-4-三氟甲基苯甲酸 | CAS号713-41-7 2-氨基-4-三氟甲基苯甲酰胺 | CAS号778-94-9 4-氰基-3-硝基三氟甲基苯 | CAS号400-98-6 2-硝基-4-三氟甲基苯胺 | CAS号98-16-8 间三氟甲苯胺 | CAS号455-24-3 4-三氟甲基苯甲酸 | CAS号109466-88-8 2-amino-4-(trif... | CAS号61500-87-6 2-氨基-4-三氟甲基苯甲酸甲酯 | CAS号328-89-2 2-溴-4-三氟甲基苯甲酸 | CAS号455-24-3 4-三氟甲基苯甲酸 | CAS号65568-55-0 2-氨基-4-三氟甲基苯甲酸乙酯 | CAS号16499-58-4 7-(三氟甲基)喹唑啉-4(3H)-酮 | CAS号16499-65-3 4-氯-7-三氟甲基喹唑啉 | CAS号1236303-09-5 2-碘-4-(三氟甲基)苯甲酸甲酯 | CAS号1214334-90-3 2-溴-4-(三氟甲基)苯甲酸甲酯 | CAS号869550-68-5 2-乙酰氨基-4-(三氟甲基)苯甲酸甲酯

4-三氟甲基苯甲酸置于a-Kohle,钯 氢气,硝酸体系中,用 甲醇 作为反应溶剂,化学反应 1.0H,反应生成 2-氨基-4-三氟甲基苯甲酸
参考文献:Giencke,Astrid; Lackner,Helmut,Liebigs Annalen Der Chemie,1990,# 6,P. 569-579
标题:Giencke,Astrid; Lackner,Helmut,Liebigs Annalen Der Chemie,1990,# 6,P. 569-579

专利信息

专利号:US-2015315143-A1
优先权日:2014-05-01
标题 :N-Heterocyclic Carbene-Catalyzed Synthesis of 2-Aryl Indoles

专利号:US-9527812-B2
优先权日:2014-05-01
标题 :N-heterocyclic carbene-catalyzed synthesis of 2-aryl indoles
发明人：SCHEIDT KARL A; HOVEY JR MICHAEL TODD; CHECK CHRISTOPHER
权利人:UNIV NORTHWESTERN
摘要:Transition metal-free catalytic methods for access to 2-arylindole compounds.

专利号:CN-115010671-A
优先权日:2022-07-20
标题:One-step synthesis method of 2-substituted quinazolinone

专利号:US-8461107-B2
优先权日:2008-04-28
标题:HCV NS3 protease inhibitors
发明人：LIVERTON NIGEL J; MCCAULEY JOHN A; BUTCHER JOHN W; GILBERT KEVIN F; MCINTYRE CHARLES J; RUDD MICHAEL T
权利人:LIVERTON NIGEL J; MCCAULEY JOHN A; BUTCHER JOHN W; GILBERT KEVIN F; MCINTYRE CHARLES J; RUDD MICHAEL T; MERCK SHARP & DOHME
摘要:The present invention relates to macrocyclic compounds of formula (I) that are useful as inhibitors of the hepatitis C virus (HCV) NS3 protease, their synthesis, and their use for treating or preventing HCV infections.

专利号:RU-2179972-C2
优先权日:1996-10-18
标 题:Bis(amides) of nitrogen-containing tricyclic carboxylic acids, method of their synthesis and pharmaceutical composition based on thereof

专利号:US-9328138-B2
优先权日:2011-11-15
标题:HCV NS3 protease inhibitors
发明人：RUDD MICHAEL T; MCCAULEY JOHN; LIVERTON NIGEL; GRISÉ-BARD CHRISTIANE; BROCHU MARIE-CHRISTINE; CHARRON SYLVIE; AULAKH VIRENDER; BACHAND BENOIT; BEAULIEU PATRICK; ZAGHDANE HELMI; HAN YONGXIN; FERRARA MARCO; HARPER STEVEN; SUMMA VINCENZO; CHACKALAMANNIL SAMUEL; VENKATRAMAN SRIKANTH; SHAH UNMESH; VELAZQUEZ FRANCISCO
权利人:MERCK SHARP & DOHME; MSD ITALIA SRL; MERCK CANADA INC
摘要:The present invention relates to macrocyclic compounds of formula (I) that are useful as inhibitors of the hepatitis C virus (HCV) NS3 protease, their synthesis, and their use for treating or preventing HCV infections.