CAS: 616-82-0; 4-Hydroxy-3-Nitrobenzoic Acid

上下游产品

3,4-Dihydroxybenzoic acid 1-methyl-4-nitrosobenzene 3,4-dinitrobenzoic acid 4-methoxycarbonylmethoxy-3-nitro-benzoic acid methyl (4-hydroxy-3-nitro)benzoate 4-hydroxy-3-nitro-benzoic acid propyl ester 4-ethoxy-3-nitrobenzoic acid 4-butoxy-3-nitro benzoic acid

4-氯-3-硝基苯甲酸置于sodium Hydroxide体系中,用 水 作为反应溶剂,以90%的收率获得产物4-羟基-3-硝基苯甲酸
参考文献:Preparation Of 3-Amino-4-Hydroxybenzoic Acids
标题:Preparation Of 3-Amino-4-Hydroxybenzoic Acids
摘要:这项发明涉及一种制备3-氨基-4-羟基苯甲酸的方法,包括(A)在酸性反应介质中将对卤苯甲酸与硝酸接触,条件下制备3-硝基-4-卤苯甲酸;(B)在反应介质中将3-硝基-4-卤苯甲酸与碱金属氢氧化物接触,条件下卤基被羟基取代,制备3-硝基-4-羟基苯甲酸或其盐;以及(C)在条件下还原3-硝基-4-羟基苯甲酸,制备4-羟基-3-氨基苯甲酸.

专利信息

专利号:US-9121110-B2
优先权日:2002-12-19
标 题 :Quasirandom structure and function guided synthesis methods
发明人：GOULIAEV ALEX HAAHR; HOLTMANN ANETTE; PEDERSEN HENRIK; FRANCH THOMAS
权利人:GOULIAEV ALEX HAAHR; HOLTMANN ANETTE; PEDERSEN HENRIK; FRANCH THOMAS; NUEVOLUTION AS
摘要:The present invention is directed to the synthesis of molecules guided by connector polynucleotides (CPNs) capable of hybridizing to complementary connector polynucleotides (CCPNs) harboring at least one functional entity comprising at least one reactive group. At least one of the CCPNs is capable of hybridizing to at least two CPNs. Each CPN will “callâ€? for one or more CCPNs capable of hybridization to the CPN. Following the formation of a supramolecular hybridization complex comprising a plurality of CPNs and a plurality of CCPNs, the reaction of reactive groups results in the formation of a molecule comprising covalently linked functional entities. The formation of the molecule involves the transfer of functional entities from one or more “donor CCPNsâ€? to at least one “acceptor CCPNâ€? with which the transferred functional entities were not associated prior to the transfer.

专利号:US-6180830-B1
优先权日:1995-11-08
标题 :Method for preparing a bimetallic ruthenium/tin catalyst and a process for the synthesis of aldehydes
发明人：JACQUOT ROLAND
权利人:RHODIA CHIMIE SA
摘要:The present invention relates to a new process for the preparation of a bimetallic ruthenium/tin catalyst. The process for the preparation of a bimetallic ruthenium/tin catalyst according to the invention is characterised by the fact that it consists in carrying out the reduction of a ruthenium complex having an electrovalency of -4 and a coordination number of 6, the ligands being either a halogen atom or an anion or a tin halide. The catalyst is further employed for the preparation of aldehydes by reduction, in the vapor phase, of carboxylic acids, esters and anhydrides.

专利号:US-4764263-A
优先权日:1987-05-18
标 题:Electrochemical synthesis of substituted aromatic amines in basic media
发明人：GREGORY THOMAS D; STUTTS KENNETH J
权利人:DOW CHEMICAL CO
摘要:Substituted amino aromatic compounds such as 3-amino-4-hydroxybenzoic acid are prepared by electrolytically reducing the corresponding nitro aromatic compound in a basic medium at temperatures below 60° C. and current densities greater than 50 milliamps per square centimeter. The aminohydroxybenzoic acids are useful in the preparation of polybenzoxazoles which are used to make fibers and composites having high strength and thermal stability.

专利号:US-5476827-A
优先权日:1991-10-24
标题 :Process for the synthesis of aldehydes and their derivatives and catalyst for use thereof
发明人：FERRERO ROSE-MARIE; JACQUOT ROLAND
权利人:RHONE POULENC CHIMIE
摘要:A process for the preparation of aldehydes by hydrogen reduction of carboxylic acids, esters or anhydrides, characterized in that the reduction conducted in the vapor phase, in the presence of a bimetallic catalyst of the ruthenium/tin type.

专利号:US-9809678-B2
优先权日:2008-09-08
标 题:Polycarbonate polyol compositions and methods
发明人：ALLEN SCOTT D; COATES GEOFFREY W; CHERIAN ANNA E; SIMONEAU CHRIS A; GRIDNEV ALEXEI A; FARMER JAY J
权利人:NOVOMER INC; SAUDI ARAMCO TECH CO
摘要:In one aspect, the present disclosure encompasses polymerization systems for the copolymerization of CO 2 and epoxides comprising 1) a catalyst including a metal coordination compound having a permanent ligand set and at least one ligand that is a polymerization initiator, and 2) a chain transfer agent having two or more sites that can initiate polymerization. In a second aspect, the present disclosure encompasses methods for the synthesis of polycarbonate polyols using the inventive polymerization systems. In a third aspect, the present disclosure encompasses polycarbonate polyol compositions characterized in that the polymer chains have a high percentage of —OH end groups and a high percentage of carbonate linkages. The compositions are further characterized in that they contain polymer chains having an embedded polyfunctional moiety linked to a plurality of individual polycarbonate chains.

专利号:US-9217012-B2
优先权日:2009-04-08
标题 :Inhibitors of protein tyrosine phosphatases
发明人：ZHANG ZHONG-YIN; ZHANG SHENG
权利人:ZHANG ZHONG-YIN; ZHANG SHENG; UNIV INDIANA RES & TECH CORP
摘要:Disclosed herein are compounds that selectively inhibit members of the PTP family of enzymes. Synthesized compounds demonstrated selective inhibition of TC-PTP. Also provided are methods of using the compounds and formulations containing the compounds. Also described is a fluorescence-tagged combinatorial library synthesis and screening method. And methods of using these compounds to effect enzyme activity both in cells and in vitro as well as method of using these compounds to treat diseases in human and animals.