CAS: 669008-26-8; 1-Methylcyclopropane-1-Sulfonamide

相似化合物

154350-29-5 849022-29-3 681808-56-0

上下游产品

CAS号849022-29-3 N-[(1-甲基环丙基)磺酰基... | CAS号669008-25-7 N-叔丁基-1-甲基环丙烷-1-磺酰胺 | CAS号923032-55-7 1-甲基环丙烷-1-磺酰氯

1-甲基-环丙烷磺酰氯置于氨体系中,化学反应 16.0H,反应生成 1-甲基环丙烷磺酰胺
参考文献:Substituted Pyrazolo[1,5-A] Pyridine As Tropomyosin Receptor Kinase (Trk) Inhibitors
标题:Substituted Pyrazolo[1,5-A] Pyridine As Tropomyosin Receptor Kinase (Trk) Inhibitors
摘要:本申请涉及一系列取代吡唑并[1,5-A]吡啶化合物,其用作肌动蛋白激酶受体激酶(trk)家族蛋白激酶抑制剂,制备方法以及包含这些化合物的药物组合物.

专利信息

专利号:US-2012095211-A1
优先权日:2010-09-22
标 题 :Substituted proline inhibitors of hepatitis c virus replication
发明人：BUCKMAN BRAD; NICHOLAS JOHN B; SEREBRYANY VLADIMIR; SEIWERT SCOTT D
权利人:BUCKMAN BRAD; NICHOLAS JOHN B; SEREBRYANY VLADIMIR; SEIWERT SCOTT D; INTERMUNE INC
摘要:The embodiments provide compounds of the general Formulae I, Ia, II, IIa, III, IIIa, IIIb, IV, IVa, IVb, V, Va, Vb, VI, VIa, VIb, and VIc, as well as compositions, including pharmaceutical compositions, comprising a subject compound. The embodiments further provide treatment methods, including methods of treating a hepatitis C virus infection and methods of treating liver fibrosis, the methods generally involving administering to an individual in need thereof an effective amount of a subject compound or composition. The embodiments also provide methods for the synthesis of subject compounds and intermediates in the synthetic methods.

专利号:US-9440991-B2
优先权日:2013-12-23
标 题:Synthesis of an antiviral compound
发明人：CAGULADA AMY; CHAN JOHANN; CHAN LINA; COLBY DENISE A; KARKI KAPIL KUMAR; KATO DARRYL; KEATON KATIE ANN; KONDAPALLY SUDHA; LEVINS CHRIS; LITTKE ADAM; MARTINEZ RUBEN; PCION DOMINIKA; REYNOLDS TROY; ROSS BRUCE; SANGI MICHAEL; SCHRIER ADAM J; SENG PAMELA; SIEGEL DUSTIN; SHAPIRO NATHAN; TANG DONALD; TAYLOR JAMES G; TRIPP JONATHAN; WALTMAN ANDREW W; YU LAWRENCE
权利人:GILEAD SCIENCES INC
摘要:The present disclosure provides processes for the preparation of a compound of formula I: n nwhich is useful as an antiviral agent. The disclosure also provides compounds and processes for the preparation of the compounds that are synthetic intermediates to the compound of formula I.

专利号:US-2017210756-A1
优先权日:2013-12-23
标题 :Synthesis of an antiviral compound

专利号:EP-3087085-B1
优先权日:2013-12-23
标题 :Synthesis of a macrocyclic hcv ns3 inhibiting tripeptide

专利号:US-8987195-B2
优先权日:2012-08-08
标 题:HCV NS3 protease inhibitors
发明人：BARA THOMAS; BHAT SATHESH; BISWAS DIPSHIKHA; BROCKUNIER LINDA; BURNETT DUANE A; CHACKALAMANNIL SAMUEL; CHELLIAH MARIAPPAN V; CHEN AUSTIN; CLASBY MARTIN; COLANDREA VINCE J; GUO ZHUYAN; HAN YONGXIN; JAYNE CHARLES; JOSIEN HUBERT; MARCANTONIO KAREN; MIAO SHOUWU; NEELAMKAVIL SANTHOSH; PINTO PATRICK; RAJAGOPALAN MURALI; SHAH UNMESH; VELAZQUEZ FRANCISCO; VENKATRAMAN SRIKANTH; XIA YAN
权利人:MERCK SHARP & DOHME; MERCK CANADA INC
摘要:The present invention relates to hepatitis C virus (HCV) NS3 protease inhibitors containing a spirocyclic moeity, uses of such compounds, and synthesis of such compounds.

专利号:US-10030033-B2
优先权日:2013-12-23
标 题 :Synthesis of an antiviral compound