CAS: 75-30-9; 2-Iodopropane

上下游产品

CAS号67-63-0 异丙醇 | CAS号420-26-8 2-氟丙烷 | CAS号56-81-5 甘油 | CAS号74-98-6 丙烷 | CAS号187737-37-7 propene | CAS号108-21-4 醋酸异丙酯 | CAS号2916-31-6 2,2-二甲基-1,3-二氧环戊烷 | CAS号67-64-1 丙酮 | CAS号102-76-1 三醋酸甘油酯 | CAS号201230-82-2 carbon monoxide | CAS号105336-21-8 3,4-dimethyl-N-... | CAS号1119-29-5 Pentanamide, 4-... | CAS号105996-41-6 (2-hydroxy-3-na... | CAS号1095565-81-3 AMG-221 | CAS号1155174-34-7 (R)-2-((1S,2S,4... | CAS号107811-48-3 2-异丙氧基-4-甲氧基苯甲醛 | CAS号55897-64-8 2-异丙基-2,3-二甲基丁腈 | CAS号34123-66-5 3-异丙基-4-甲氧基苯甲醛 | CAS号35826-59-6 4-异丙氧基苯甲酸甲酯 | CAS号3360-16-5 N-异丙基-1,3-二氨基丙烷

丙烷置于ccl4*2Ali3体系中,用 二氯甲烷 作为反应溶剂,化学反应 1.5H,以50%的收率获得产物2-碘代丙烷
参考文献:First Examples Of Superelectrophile Initiated Iodination Of Alkanes And Cycloalkanes
标题:First Examples Of Superelectrophile Initiated Iodination Of Alkanes And Cycloalkanes
摘要:Direct Iodination Of Alkanes And Cycloalkanes In The Presence Of Superelectrophiles Has Been Accomplished For The First Time. The Reactions Of Saturated Hydrocarbons With I-2 In The Presence Of Ccl4.2All(3) At-20Degreesc Afforded Monoiodides In Good Yields And Selectivities. (C) 2002 Elsevier Science Ltd. All Rights Reserved.
DOI:10.1016/s0040-4039(01)02371-1

专利信息

专利号:US-7943594-B2
优先权日:2002-07-10
标 题 :Solid-phase and solution-phase synthesis of glycosylphosphatidylinositol glycans
发明人：SEEBERGER PETER H; HEWITT MICHAEL C; SNYDER DANIEL A
权利人:MASSACHUSETTS INST TECHNOLOGY
摘要:One aspect of the present invention relates to solution-phase approaches to GPI synthesis. Another aspect of the present invention relates to key building blocks, and syntheses thereof, useful for GPI assembly. Yet another aspect of the invention relates to an automated method for the synthesis of GPIs and fragments thereof.

专利号:US-5545568-A
优先权日:1992-09-14
标题:Solid phase and combinatorial synthesis of compounds on a solid support
发明人：ELLMAN JONATHAN A
权利人:UNIV CALIFORNIA
摘要:Methods, compositions, and devices for synthesizing combinatorial libraries of various useful compounds, such as benzodiazepines, prostaglandins, β-turn mimetics and glycerol-derived drugs is described. In order to expediently synthesize such combinatorial libraries of derivatives based upon these core structures, a general methodology for the solid phase synthesis of these derivatives is also provided. This disclosure thus also describes an important extension of solid phase synthesis methods to nonpolymeric organic compounds.

专利号:EP-1721894-A1
优先权日:2005-05-13
标题 :Process for the synthesis of prostaglandin derivatives
发明人：LISI GIUSEPPE
权利人:TECHNOPHARMA SA
摘要:An alternative method for the synthesis of prostaglandin F analogues, in particular, analogues of PGF 2α and specifically for the synthesis of latano-prost, wherein the transformation of the lactone intermediate (5)n ninto the corresponding lactol (7)n nis carried out by treating the lactone intermediate (5) with a silane, preferably polymethylhydrosiloxane (PMHS), in the presence of a titanocene - and preferably titanocene fluoride. n The method enables considerable production economies with respect to the conventional reduction of lactone with diisobutylaluminum hydride (DIBAL-H).

专利号:WO-2017033128-A1
优先权日:2015-08-25
标题 :Biphenyl-substitued 4-amino-butyric acid derivatives and their use in the synthesis of nep inhibitors
发明人：HOOK DAVID; KU JIE; ZHOU JIANGUANG
权利人:NOVARTIS AG; HOOK DAVID; KU JIE; ZHOU JIANGUANG
摘要:The invention relates to a novel process, novel process steps and novel intermediates useful in the synthesis of pharmaceutically active compounds, in particular neutral endopeptidase (NEP) inhibitors and prodrugs thereof.

专利号:US-12240835-B2
优先权日:2018-09-18
标题:Substituted benzamides as intermediates in the synthesis of inhibitors of tyrosine kinase enzymatic activity
发明人：ROMERO F ANTHONY; KIRSCHBERG THORSTEN A; HALCOMB RANDALL; XU YINGZI
权利人:TERNS PHARMACEUTICALS INC
摘要:Provided herein are compounds, preferably compounds inhibiting tyrosine kinase enzymatic activity of a protein selected from Abelson protein (ABL1), Abelson-related protein (ABL2), or a chimeric protein BCR-ABL1, compositions thereof, and methods of their preparation, and methods of inhibiting tyrosine kinase enzymatic activity of a protein selected from Abelson protein (ABL1), Abelson-related protein (ABL2), or a chimeric protein BCR-ABL1, and methods for treating diseases wherein modulation of BCR-ABL1 activity prevents, inhibits, or ameliorates the pathology and/or symptomology of the disease. Intermediates such as compounds of Formula (S23), which are useful in the synthesis of compounds inhibiting tyrosine kinase enzymatic activity of a protein selected from Abelson protein (ABL1), Abelson-related protein (ABL2), or a chimeric protein BCR-ABL1, are also provided.

专利号:US-10173993-B2
优先权日:2015-12-09
标题 :Process for the synthesis of sulfones and sulfonamides
发明人：VON WOLFF NIKLAS; CHAR JOËLLE; CANTAT THIBAULT
权利人:COMMISSARIAT ENERGIE ATOMIQUE
摘要:A one pot single step process is described for the synthesis of a compound, including a labeled compound, containing a sulfonyl functional group comprising the step of mixing together a silane, an SO 2 source, an electrophilic compound, an activating compound and optionally a metal catalyst. A process for producing tracers from a labeled sulfonyl containing compound prepared by the described process is also included.