CAS: 1069-08-5; Dichloro(Diethylamino)Phosphine

上下游产品

diethylamine N,N-diethylaminodibenzylphosphine N,N-diethyl-1,1,1-trimethylsilanamine difluoro diethylamino phosphineChlor-diethylamino-cyclohexyl-phosphan P,P-diethyl-N,N-diethylphosphinous amide difluoro diethylamino phosphine hexaethylphosphoric triamide

二乙胺置于三乙胺,三氯化磷体系中,用 乙醚 用作溶剂,化学反应 24.0H,反应生成二乙基二氯磷
参考文献:磷酸二羟基丙酮的改进合成
标题:磷酸二羟基丙酮的改进合成
摘要:已经开发了用于合成磷酸二羟基丙酮(dhap)的改进方法.在1,2,4-三唑或四唑存在下,2,5-二乙氧基对二恶烷-2,5-二甲醇(1)与三价磷酸化试剂二苄基-N,N-二乙基亚磷酰胺(ddp)的反应用h 2 O 2氧化得到2,5-二乙氧基-对-二恶烷-2,5-二甲醇-O-2 1-O-5 1-双(磷酸)四苄酯(2),产率为98%.然后将化合物2在h 2-Pd / C存在下氢化,中和后得到2,5-二乙氧基-对二恶烷-2,5-二甲醇-O-2 1-O-5 1-双(磷酸盐)稳定的三钠盐(3),收率84%.用dowex 50(h +)处理3会生成2当量的dhap.
Doi:10.1016/s0040-4020(01)81796-8

专利信息

专利号:US-7557096-B2
优先权日:1998-01-09
标题 :Synthesis of combretastatin A-4 prodrugs and trans-isomers thereof
发明人：PETTIT GEORGE R; RHODES MONTE R
权利人:UNIV ARIZONA
摘要:Combretastatin A-4 has been previously selected for pre-clinical development as antineoplastic agent. However, it is essentially insoluble in water. New water soluble derivatives of combretastatin A-4 and its qualified analogs have been discovered and synthesized through a multistage process using other derivatives of combretastatin A-4 as intermediates. These water soluble derivatives are herein denominated as “Combretastatin A-4 Prodrugsâ€?.

专利号:US-12291489-B2
优先权日:2016-07-01
标 题 :Synthesis of nanocomposites and their use in enhancing plant nutrition
发明人：BISWAS PRATIM; RALIYA RAMESH
权利人:BISWAS PRATIM; RALIYA RAMESH; WASHINGTON UNIVERSITY ST LOUIS
摘要:The present disclosure is related to the development of improved fertilizer for precision and sustainable agriculture. A method was developed wherein efficient NPK nanocomposite for plant nutrition was synthesized in a single step using aerosol science and technology concepts. Further a formulation was prepared by addition of ZnO, TiO 2 and other nanoparticles to the NPK nanocomposite. Also, an aerosol based foliar application technique was developed for the precise delivery of nanoparticles to the plants.

专利号:US-6972320-B2
优先权日:2000-05-12
标题 :Ligation method and reagents to form an amide bond
发明人：RAINES RONALD T; KIESSLING LAURA L; NILSSON BRADLEY L
权利人:WISCONSIN ALUMNI RES FOUND
摘要:Methods and reagents for the formation of amide bonds between an activated carboxylic acid derivative and an azide useful in the synthesis of peptides, proteins and derivatized or labeled amino acids, peptide or proteins. The method involves the formation of a phosphinothioester which reacts with an azide resulting in amide formation. The invention provides phosphinothiol reagents which convert activated carboxylic acid derivatives to phosphinothioesters which then react with azides to form an amide bond. The methods and reagents of the invention can be used for stepwise synthesis of peptides on solid supports or for the ligation to two or more amino acids, two or more peptide or two or more protein fragments.

专利号:US-2019202750-A1
优先权日:2016-07-01
标 题 :Synthesis of nanocomposites and their use in enhancing plant nutrition

专利号:US-7279466-B2
优先权日:1998-01-09
标题:Synthesis of combretastatin A-4 prodrugs and trans-isomers thereof

专利号:US-2007073077-A1
优先权日:1998-01-09
标题:Synthesis of combretastatin A-4 prodrugs and trans-isomers thereof