CAS: 2150-43-8; Methyl 3,4-Dihydroxybenzoate

上下游产品

CAS号67-56-1 甲醇 | CAS号99-50-3 原儿茶酸 | CAS号149-73-5 原甲酸三甲酯 | CAS号3943-74-6 香草酸甲酯 | CAS号99-76-3 尼泊金甲酯 | CAS号484018-34-0 methyl 4-(cyclo... | CAS号74997-71-0 lithium 4-(meth... | CAS号326-56-7 甲基 1,3-苯并二茂-5-羧酸酯 | CAS号5026-62-0 尼泊金甲酯钠 | CAS号1000180-42-6 2-(3,4-dihydrox... | CAS号476168-17-9 2-氨基-4,5-双(2-甲氧... | CAS号94-53-1 胡椒酸 | CAS号3693-53-6 亚甲基二氨基甲酸酯 | CAS号4143-64-0 3',4'-二羟基黄酮 | CAS号491-70-3 木犀草素; 3',4',5,7... | CAS号39635-11-5 3,4-二羟基苯甲酰肼 | CAS号180678-33-5 3,4-dihexadecox... | CAS号180678-39-1 4-(3,4-didecoxy... | CAS号180678-30-2 methyl 3,4-dihe... | CAS号179688-14-3 3,4-双{[2-(甲基氧基)...

3-羟基-4-甲氧基苯甲酸甲酯置于aluminium(III) Iodide,乙酸乙酯,N,N'-二异丙基碳二亚胺体系中,用 乙腈 用作溶剂,化学反应 2.0H,以68%的收率获得3,4-二羟基苯甲酸甲酯
参考文献:乙酸乙酯作为助溶剂和三碘化铝中的牺牲酯促进了香草酸甲酯的化学选择性脱甲基
标题:乙酸乙酯作为助溶剂和三碘化铝中的牺牲酯促进了香草酸甲酯的化学选择性脱甲基
摘要:通过使用由三碘化铝,1,3-二异丙基碳二亚胺和乙酸乙酯组成的三元试剂体系,公开了通过化学选择性醚裂解香草酸甲酯而对原儿茶酸甲酯的合成方法.乙酸乙酯用作助溶剂和牺牲酯.类似地将异香草酸甲酯,香草酸乙酯和阿魏酸甲酯脱甲基,分别以适当的收率获得原儿茶酸甲酯,原儿茶酸乙酯和咖啡酸甲酯.
Doi:10.1016/j.Tetlet.2017.07.089

专利信息

专利号:US-9777034-B2
优先权日:2013-05-21
标题 :Modular synthesis of amphiphilic Janus glycodendrimers and their self-assembly into glycodendrimersomes
发明人：PERCEC VIRGIL
权利人:UNIV PENNSYLVANIA
摘要:The invention concerns compounds of the formula (I) wherein: Y 1 and Y 2 are independently a monosaccharide or disaccharide; X 1 and X 2 are independently —(R 9 —O) m —, —(R 10 ) p —, —O—(R 11 —O) q —, —R 16 —O—R 17 —O— or a covalent bond; Q 1 and Q 2 are independently a nitrogen-containing heterocycle moiety; Z 1 and Z 2 are independently —(O—R 7 )—, —(O—C(â•?O)—R 8 )a-, —O—C(â•?O)—R 12 —C(=0)-R 13 —, —O—C(â•?O)—R 14 —C(â•?O)—R 15 or a covalent bond; R 7 -R 17 are each independently C 1 -C 6 alkyl; R 1 -R 6 are each independently a linear or branched alkyl group; b, c, d, e, f, and g are 0 or 1, provided b+c+d equals at least 2 and e+f+g equals at least 2; and a, m, p, and q are each an integer from 1-6.

专利号:US-2008039473-A1
优先权日:2006-08-08
标题:Preparation and utility of substituted quinazoline compounds with alpha-adrenergic blocking effects
发明人：GANT THOMAS G; SARSHAR SEPEHR
权利人:AUSPEX PHARMACEUTICALS INC
摘要:The present disclosure is directed to modulators of alpha-adrenergic receptors and pharmaceutically acceptable salts and prodrugs thereof, the chemical synthesis thereof, and the use of such compounds for the treatment and/or management of hypertension, cardiac failure, prostatitis, and benign prostatic hyperplasia, and any other condition in which it is beneficial to modulate an alpha-adrenergic receptor.

专利号:US-7745490-B2
优先权日:2004-05-12
标题 :Substituted N-aryl benzamides and related compounds for treatment of amyloid diseases and synucleinopathies
发明人：SNOW ALAN D; NGUYEN BETH P; LAKE THOMAS P; CASTILLO GERARDO M; WEIGELE MANFRED
权利人:PROTEOTECH INC
摘要:Substituted n-aryl benzamides, related compounds and their pharmaceutically acceptable derivatives, their synthesis, pharmaceutical compositions containing them, and their use in the treatment of amyloid diseases, including Aβ amyloidosis, such as observed in Alzheimer's disease, IAPP amyloidosis, such as observed in type 2 diabetes, and synucleinopathies, such as observed in Parkinson's disease, and the manufacture of medicaments for such treatment are provided.

专利号:US-7872013-B2
优先权日:2006-08-16
标 题 :Preparation and utility of opioid analgesics
发明人：GANT THOMAS G; SARSHAR SEPEHR
权利人:AUSPEX PHARMACEUTICALS INC
摘要:The present disclosure is directed to modulators of opiate- and/or NMDA receptors and pharmaceutically acceptable salts and prodrugs thereof, the chemical synthesis thereof, and the use of such compounds for the treatment and/or management of pain, anxiety, neurodegeneration, drug dependence, coughing, muscular tension, and/or glaucoma and any other condition in which it is beneficial to modulate an opiate- and/or NMDA receptor.

专利号:US-2016108076-A1
优先权日:2013-05-21
标题:Modular synthesis of amphiphilic janus glycodendrimers and their self-assembly into glycodendrimersomes

专利号:US-2011015119-A1
优先权日:2009-06-24
标题:Novel semi-synthetic glycopeptides as antibacterial agents
发明人：CHU DANIEL; YE TAO; WANG BING
权利人:LEAD THERAPEUTICS INC
摘要:Semi-synthetic glycopeptides having antibacterial activity are described, in particular, the semi-synthetic glycopeptides described herein are made by chemical modification of a glycopeptide (Compound A, Compound B, Compound H or Compound C) or monosaccharide made by hydrolyzing the disaccharide moiety of the amino acid-4 of the parent glycopeptide in acidic medium to give the amino acid-4 monosaccharide; conversion of the monosaccharide to the amino-sugar derivative; acylation of the amino substituent on the amino acid-4 amino-substituted sugar moiety on these scaffolds with certain acyl groups; and conversion of the acid moiety on the macrocyclic ring of these scaffolds to certain substituted amides. Key reaction is the treatment of properly protected intermediate compound with isocyanate. Also provided are methods for the synthesis of the compounds, pharmaceutical compositions containing the compounds, and methods of use of the compounds for the treatment and/or prophylaxis of diseases, especially bacterial infections.