专利号:US-10919904-B2 优先权日:2016-08-17 标 题 :Northern-southern route to synthesis of bacteriochlorins 发明人:LIU YIZHOU; LINDSEY JONATHAN S; ALLU SRINIVASA RAO; FUJITA HIKARU 权利人:UNIV NORTH CAROLINA STATE 摘要:Described herein are chlorins, bacteriochlorins, methods and intermediates for the synthesis of bacteriochlorins, and methods of using such bacteriochlorins for, among other things, diagnostic and therapeutic purposes such as luminescent compounds in flow cytometry, and as active agents in photodynamic therapy (PDT).
专利号:US-2022288005-A1 优先权日:2019-07-26 标题:Synthesis of pro-resolving analogs and compositions therefor 发明人:VAN DYKE THOMAS E; SERHAN CHARLES N 权利人:NOCENDRA INC 摘要:This disclosure relates to methods of synthesizing certain lipoxin analogs (e.g., lipoxin mimetics, etc.) and pharmaceutical compositions comprising these pro-resolving compounds. Methods of administering the lipoxin mimetics (e.g., lipoxin A4 mimetics, lipoxin B4 mimetics, etc.) to patients in need thereof are also provided.
专利号:WO-2023064991-A1 优先权日:2021-10-22 标题 :Process for preparing bicyclic glycine-proline compounds and monocyclic glycine-proline intermediates thereof 发明人:SCOTT JEREMY PETER; KEEN STEPHEN PHILIP; ESPENSEN GEORGE MAX; PARRY-JONES DAVID; LAWRENCE RONNIE MAXWELL; BLOWER CLIVE JOHN 权利人:NEUREN PHARMACEUTICALS LTD 摘要:The present disclosure generally relates to a process for the synthesis of bicyclic glycine-proline compounds, and monocyclic glycine-proline intermediates thereof. In particular, the present disclosure also relates to a process for the synthesis of cyclic G-2-AllylP and its analogues. The present disclosure also relates to a process for the synthesis of optionally protected monocyclic glycine-proline intermediates. The present disclosure also relates to a process for the synthesis of esterified glycine-proline intermediates. The present disclosure also relates to compounds prepared by the processes and the use of such compounds to prepare compositions and to treat disorders.
专利号:US-2019256521-A1 优先权日:2016-08-17 标题:Northern-southern route to synthesis of bacteriochlorins
专利号:EP-2107067-A1 优先权日:2008-04-03 标 题 :Boron catalysed peptide synthesis 发明人:QUAEDFLIEG PETER JAN LEONARD MARIO; NUIJENS TIMO; VRIES DE JOHANNES GERARDUS; KALKEREN VAN HENRI ANTONIUS 权利人:DSM IP ASSETS BV 摘要:The invention relates to a method of synthesising a dipeptide, an oligopeptide or polypeptide comprising coupling a first amino acid or peptide to a second amino acid or peptide in the presence of a boron compound comprising a boron oxygen bond, which boron compound catalyses the formation of a peptidic bond, wherein one of the stereoisomers is formed in excess of the other stereoisomer or stereoisomers.
专利号:WO-2009073246-A1 优先权日:2007-12-06 标 题 :Method for the synthesis of iridium (iii) complexes with sterically demanding ligands