CAS: 35112-28-8; Methyl 2,4-Dichlorobenzoate

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CAS号50-84-0 2,4-二氯苯甲酸 | CAS号107-06-2 1,2-二氯乙烷 | CAS号67-56-1 甲醇 | CAS号874-42-0 2,4-二氯苯甲醛 | CAS号1126-46-1 甲基-4-氯苯甲酸甲酯 | CAS号17287-03-5 三甲基氢氧化硫,甲醇溶液 | CAS号56882-52-1 2,4-二氯苯甲酸乙酯 | CAS号124-38-9 二氧化碳 | CAS号29898-32-6 2,4-二氯-1-碘苯 | CAS号74-88-4 碘甲烷 | CAS号39528-61-5 2,4-二氯苯甲腈 | CAS号1126-46-1 甲基-4-氯苯甲酸甲酯 | CAS号7364-20-7 4-乙基苯甲酸甲酯 | CAS号1147858-85-2 甲基 2,4-二乙基苯酸盐 | CAS号5814-06-2 2,4-二氯苯甲酰肼 | CAS号2459-10-1 苯-1,2,4-三甲酸三甲酯 | CAS号1777-82-8 2,4-二氯苄醇 | CAS号73268-35-6 6-chloro-9H-dib... | CAS号66896-64-8 2,4-dichloro-N-... | CAS号81450-58-0 5-(2,4-dichloro...

专利信息

专利号:MX-2015001935-A
优先权日:2012-08-13
标 题 :INTERMEDIARY FOR SYNTHESIS OF 1- (2-DEOXI-2-FLUORO-4-TIO-BETA-D-A RABINOFURANOSIL) CITOSINE, INTERMEDIARY FOR SYNTHESIS OF TIONUCLEOSIDE AND METHODS TO PRODUCE THESE INTERMEDIARIES.

专利号:US-8592583-B2
优先权日:2009-11-04
标 题 :Process for the preparation of 5-(2-amino-pyrimidin-4-yl)-2-aryl-1H-pyrrole-3-carboxamides
发明人：D ANELLO MATTEO; RE MARCO
权利人:D ANELLO MATTEO; RE MARCO; NERVIANO MEDICAL SCIENCES SRL
摘要:The invention relates to a process for the preparation of 5-(2-amino-pyrimidin-4-yl)-2-aryl-1H-pyrrole-3-carboxamides and to the useful intermediate compounds of such process. The process allows to obtain the desired products in high yields and purity. The synthesis is starting from the coupling of an acetal with a beta-ketoester; the resultant compound is acetylated and then reacted with a dialkyl acetal of N,N-dimethylformamide to give an intermediate which is cyclized to 5-(2-amino-pyrimidin-4-yl)-2-aryl-1H-pyrrole-3-carboxylic ester; the carboxylic ester is then hydrolyzed and the resultant carboxylic acid is finally condensed with an appropriate form of ammonia to give the desired carboxamide. The compounds prepared according to the process of the invention are endowed with protein kinase inhibiting activity and, more particularly, Cdc7 or Cdc7/Cdks inhibiting activity. The compounds are useful in the treatment of a variety of cancers, cell proliferative disorders and diseases associated with protein kinases.

专利号:US-7132092-B2
优先权日:2002-02-08
标 题:Metallized mesoporous silicate and method of oxidation with the same
发明人：HAGIYA KOJI
权利人:SUMITOMO CHEMICAL CO
摘要:A metallized mesoporous silicate which is obtained by (i) reacting (a) either a metal peroxide obtained by the reaction of an aqueous hydrogen peroxide solution with at least one metal or metal compound selected from the group consisting of the following 1) to 4) 1) tungsten 2) molybdenum 3) vanadium 4) compounds comprising 4 a ) any of tungsten, molybdenum, and vanadium and 4 b ) at least one element selected from Groups 13 to 16 (excluding oxygen) or a solution of the metal peroxide with (b) a silicon compound in the presence of an alkylamine or a quaternary ammonium salt and separating the resultant silicate; and a process for producing the metallized mesoporous silicate. Also provided is a method of organic synthesis with the silicate.