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CAS号403-17-8 4-氯-3-氟苯甲酸 | CAS号137504-86-0 4-氯-3-氟苯硼酸 | CAS号251570-03-3 3-氟-4-氯苯乙腈 | CAS号170793-00-7 4-氯-3-氟苯基溴化镁 | CAS号960000-93-5 2-溴-4-氟-5-氯硝基苯 | CAS号60810-59-5 2-(4-chloro-3-f...2-氯-5-溴苯胺,亚硝酸,氟硼酸 以74%的收率获得产物
参考文献:Cervena I.; Metysova J.; Svatek E.; Kakac B.; Holubek J.; Hrubantova M.; +,Collect. Czech. Chem. Communs,1976,41,No 3,881-905
标题:Cervena I.; Metysova J.; Svatek E.; Kakac B.; Holubek J.; Hrubantova M.; +,Collect. Czech. Chem. Communs,1976,41,No 3,881-905
专利信息
专利号:US-2025179012-A1
优先权日:2022-03-04
标 题:Synthesis of sulfur(vi) compounds and reagents for same
发明人:LOPCHUK JUSTIN MATTHEW; SHULTZ ZACHARY
权利人:H LEE MOFFITT CANCER CT & RES
摘要:This disclosure provides reagents and processes for the synthesis of organic compounds, more particularly reagents and processes for the asymmetric synthesis of sulfur (VI) containing organic compounds.
专利号:WO-2023168108-A2
优先权日:2022-03-04
标 题 :Synthesis of sulfur(vi) compounds and reagents for same
专利号:US-11286268-B1
优先权日:2019-07-02
标题:EIF4E-inhibiting compounds and methods
发明人:SPERRY SAMUEL; XIANG ALAN X; ERNST JUSTIN T; REICH SIEGFRIED H; SPRENGELER PAUL A; SHAGHAFI MIKE; MICHELS THEO; NILEWSKI CHRISTIAN; TRAN CHINH VIET; PACKARD Garrick Kenneth; GRUBBS ALAN; URKALAN KAVERI; MUKAIYAMA TAKASUKE
权利人:EFFECTOR THERAPEUTICS INC
摘要:The present invention provides synthesis, pharmaceutically acceptable formulations and uses of compounds in accordance with Formula I, or a stereoisomer, tautomer or pharmaceutically acceptable salt thereof. n n n n n n n n n n For Formula I compounds X 1 , X 2 , X 3 , X 4 , X 5 , X 6 , Q, L 1 , L 2 , Y, R 1 , R 2 , R 3 , R 4 , R 5 , R 6 , R 7 , R 8 and rings A, B and C are as defined in the specification. The inventive Formula I compounds are inhibitors of eIF4e and find utility in any number of therapeutic applications, including but not limited to treatment of inflammation and various cancers.