CAS: 89-77-0; 2-Amino-4-Chlorobenzoic Acid

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CAS号50-84-0 2,4-二氯苯甲酸 | CAS号6280-88-2 4-氯-2-硝基苯甲酸 | CAS号66909-52-2 2,4-dichloroben... | CAS号34662-32-3 4-氯-2-硝基苯甲腈 | CAS号89-63-4 邻硝基对氯苯胺 | CAS号6341-92-0 6-氯靛红 | CAS号5900-59-4 2-氨基-4-氯苯甲酰胺 | CAS号5900-56-1 2-乙酰氨基-4-氯苯甲酸 | CAS号5900-55-0 5-氯-2-甲基乙酰苯胺 | CAS号61680-22-6 7-chloro-3-(3-c... | CAS号111218-71-4 [4-(4-amino-7-c... | CAS号111218-75-8 1-(4-Amino-7-ch... | CAS号111218-91-8 2,7-Dichloroqui... | CAS号31374-18-2 7-氯-4(3H)-喹唑啉酮 | CAS号40928-13-0 4-氯靛红酸酐 | CAS号38154-43-7 4,7-二氯-2-甲基喹唑啉 | CAS号50-84-0 2,4-二氯苯甲酸 | CAS号19993-65-8 2-[(2-carboxy-5... | CAS号206350-07-4 2-Amino-4-chlor...

2,4-二氯苯甲酸置于ammonium Hydroxide体系中,126.0~129.0 °C,1.22 Mpa 条件下,反应 6.0H,以88%的收率获得产物2-氨基-4-氯苯甲酸
参考文献:Synthesis And Antileishmaniasis Activity Of 2-[2'-Chlorostyryl]-4-[δ-Diethyl-Amino-α-Methylbutylamino]-7-Chloroquinazoline Diphosphate
标题:Synthesis And Antileishmaniasis Activity Of 2-[2'-Chlorostyryl]-4-[δ-Diethyl-Amino-α-Methylbutylamino]-7-Chloroquinazoline Diphosphate
摘要:
DOI:10.1007/bf00764884

专利信息

专利号:US-5783577-A
优先权日:1995-09-15
标题 :Synthesis of quinazolinone libraries and derivatives thereof
发明人：HOUGHTEN RICHARD A; OSTRESH JOHN M
权利人:TREGA BIOSCIENCES INC
摘要:The present invention provides synthetic combinatorial libraries of organic compounds based on the quinazolinone ring.

专利号:US-4761413-A
优先权日:1986-12-22
标 题:1,5-epoxy-2,3,4,5-tetrahydro-1H-3-benzazepins and use in treatment of ulcers
发明人：WACHTER MICHAEL P; KARANEWSKY DONALD S
权利人:ORTHO PHARMA CORP
摘要:The synthesis of epoxybenzazepin compounds is described. The novel compounds have anti-ulcer activity.

专利号:US-4855426-A
优先权日:1986-12-22
标题:Process of preparing 1,5-epoxy-2,3,4,5-tetrahydro-1H-3-benzazepins
发明人：WACHTER MICHAEL P; KARANEWSKY DONALD S
权利人:ORTHO PHARMA CORP
摘要:The synthesis of epoxybenzazepin compounds is described. The novel compounds have anti-ulcer activity.

专利号:US-6187923-B1
优先权日:1998-11-09
标题 :Process for the synthesis of quinazolinones
发明人：DENER JEFFREY MARK; LY CUONG QUOC
权利人:AXYS ADVANCED TECHNOLOGIES INC
摘要:The present invention provides a process for synthesizing a compound or a library of compounds of Formula 1A and 1B:

专利号:US-4308206-A
优先权日:1980-03-17
标 题:Process for preparing derivatives of 5,11-dihydro-6h-pyrido[2,3-b][1,4]-benzodiazepin-6-one, and the final derivatives and synthesis intermediates obtained thereby
发明人：GERSZBERG SZEPSEL
权利人:MICROSULES ARGENTINA SA
摘要:This invention relates to a process for preparing derivatives of 5,11-dihydro-6H-pyrido[2,3-b][1,4]-benzodiazepin-6-one of general formula (I) ##STR1## in which R is hydrogen, halogen or methyl; n R 1 and R 2 are linear or branched C 2 -C 4 alkyl groups, which alternatively may be joined together to give a piperazine cycle which can be substituted in position 4 with a methyl, ethyl or benzyl group, n and their salts with organic and inorganic acids, characterised by comprising the following stages: n (a) reacting a compound of general formula (X), ##STR2## in which R has the meaning heretofore defined, with 2-cloro-3-amino-pyridine of formula (III) ##STR3## in the presence of polyphosphoric acid, to give an intermediate of general formula (II) ##STR4## (b) reacting said intermediate with a compound of general formula (XI) ##STR5## in which R 1 and R 2 have the meaning heretofore defined and R 3 is a hydroxyl or halogen, in an inert solvent at a maximum temperature equal to the solvent boiling point, to give said derivatives of general formula (I). n The invention also relates to the final compounds thus obtained, and the synthesis intermediates obtained during the course of said process. n The final products of formula (I) are of great interest in the pharmaceutical field.

专利号:US-4719053-A
优先权日:1980-08-01
标题 :Beta-chloroethylsulfonylmethyl-benzoic halides as intermediates
发明人：SCHLAEFER LUDWIG; HAEHNLE REINHARD
权利人:HOECHST AG
摘要:New beta -chloroethylsuflonylmethyl-benzoic acid halides which can serve as fibre-reactive anchors for thesynthesis of novel organic, water-soluble compounds, preferably dyestuffs, having fibre-reactive and fibre-finishing properties, such as preferably dyestuff properties, and containing, as a fibre-reactive group, one or two beta -chloroethylsufonylmethylbenzoic acid amide groups. For the synthesis of these novel fibre-finishing compounds, said new beta -chloroethylsulfonylmethyl-benzoic acid halide compounds are reacted with an organic, water-soluble compound having fibre-finishing properties and continuing one or two amino groups. Also precursors of the fibre-finishing, fibre-reactive compounds, containing said beta -chloroethylsulfonylmethyl-benzxoic acid amid grouping, can be employed for their synthesis. The novel fibre-finishing compounds can be applied onto suitable fibre materials, such as especially cellulose fibre material and natural or synthetic polyamide fibre materials, and fixed on these fibre materials in a manner similar to application and fixation methods usual in the technique for fibre-reactive compounds. The fibre-finished material, such as dyed material, shows very good wet fastnesses.