CAS: 446-32-2; 2-Amino-4-Fluorobenzoic Acid

上下游产品

CAS号394-01-4 4-氟-2-硝基苯甲酸 | CAS号2475-81-2 2-氨基-4-氟苯甲酸甲酯 | CAS号60-00-4 乙二胺四乙酸 | CAS号1006-41-3 2-溴-4-氟苯甲酸 | CAS号1863-63-4 苯甲酸铵 | CAS号446-10-6 4-氟-2-硝基甲苯 | CAS号394-27-4 2-乙酰氨基-4-氟苯甲酸 | CAS号367-29-3 5-氟-2-甲基苯胺 | CAS号366-49-4 2-乙酰氨基-4-氟甲苯 | CAS号364-78-3 4-氟-2-硝基苯胺 | CAS号394-27-4 2-乙酰氨基-4-氟苯甲酸 | CAS号557770-90-8 7-(3-氯丙氧基)-4-氯喹唑啉 | CAS号345-29-9 4-氟水杨酸 | CAS号557770-89-5 7-(3-羟基-丙氧基)-3H... | CAS号321-50-6 7-氟-2H-3,1-苯并噁嗪... | CAS号197783-88-3 2-氨基-4-氟苄醇 | CAS号80517-22-2 2-氨基-4-氟苯腈 | CAS号862274-39-3 6-氟-1H-吲唑-3-醇 | CAS号79-37-8 草酰氯 | CAS号59-31-4 2-羟基喹啉

4-氟-2-硝基苯胺置于硫酸,乙酸酐,三氯化铁,一水合肼,溶剂黄146,Sodium Nitrite体系中,用 乙醇 作为反应溶剂,化学反应 18.0H,反应生成 2-氨基-4-氟苯甲酸
参考文献:Protiva,Miroslav; Jilek,Jiri; Rajsner,Miroslav,Collection Of Czechoslovak Chemical Communications,1986,Vol. 51,# 3,P. 698-722
标题:Protiva,Miroslav; Jilek,Jiri; Rajsner,Miroslav,Collection Of Czechoslovak Chemical Communications,1986,Vol. 51,# 3,P. 698-722

专利信息

专利号:US-6730790-B2
优先权日:2002-03-01
标 题:Chlorinated heterocyclic compounds and methods of synthesis
发明人：KWIATKOWSKI STEFAN; GOLINSKI MIROSLAW
权利人:R T ALAMO VENTURES I LLC
摘要:Compositions of the present invention comprise chlorinated heterocyclic compounds, including racemic monochloroflosequinan, purified enantiomers of monochloroflosequinan and the sulfone derivative of monochloroflosequinan. The methods of the present invention comprise the synthesis of racemic monochloroflosequinan and derivatives thereof, including the sulfone derivative. Intermediates in the synthesis are also provided. The methods further comprise the synthesis of enantiomers of monochloroflosequinan.

专利号:US-7034040-B2
优先权日:2002-03-01
标题:Fluorinated heterocyclic compounds and methods of synthesis
发明人：KWIATKOWSKI STEFAN; GOLINSKI MIROSLAW
权利人:R T ALAMO VENTURES I
摘要:Compositions of the present invention comprise fluorinated heterocyclic compounds, including monofluoroflosequinan and difluoroflosequinan. The methods of the present invention comprise the synthesis of monofluoroflosequinan and difluoroflosequinan.

专利号:US-7045627-B2
优先权日:2002-03-01
标题:Dichlorinated heterocyclic compounds and methods of synthesis
发明人：KWIATKOWSKI STEFAN; GOLINSKI MIROSLAW
权利人:R T ALAMO VENTURES I LLC
摘要:Compositions of the present invention comprise dichlorinated heterocyclic compounds, including dichloroflosequinan. The methods of the present invention also comprise the synthesis of dichloroflosequinan.

专利号:US-6872831-B2
优先权日:2002-03-01
标题:Carboxylated heterocyclic compounds and methods of synthesis
发明人：KWIATKOWSKI STEFAN; GOLINSKI MIROSLAW
权利人:R T ALAMO VENTURES I LLC
摘要:Compositions of the present invention comprise carboxylated heterocyclic compounds, including carboxyflosequinan. The methods of the present invention also comprise the synthesis of carboxyflosequinan.

专利号:US-5783577-A
优先权日:1995-09-15
标题 :Synthesis of quinazolinone libraries and derivatives thereof
发明人：HOUGHTEN RICHARD A; OSTRESH JOHN M
权利人:TREGA BIOSCIENCES INC
摘要:The present invention provides synthetic combinatorial libraries of organic compounds based on the quinazolinone ring.

专利号:US-7084275-B2
优先权日:2001-10-25
标题 :Stereospecific enrichment of heterocyclic enantiomers
发明人：KWIATKOWSKI STEFAN; GOLINSKI MIROSLAW; KUPPER JOSEPH
权利人:R T ALAMO VENTURES I LLC
摘要:The present invention describes methods for the stereoselective synthesis of heterocyclic enantiomers. The methods of the present invention incorporate the stereo-preferred oxidation of quinolone thiomethyl intermediates by optically active camphor based oxaziridines to provide R(+) or S(−) quinolone methylsulfinyl derivatives.