CAS: 50670-49-0; 4-Bromo-4'-Methyl-1,1'-Biphenyl

上下游产品

CAS号644-08-6 4-甲基联苯 | CAS号201230-82-2 carbon monoxide | CAS号5720-05-8 对甲基苯基硼酸 | CAS号673-40-5 4-溴硼酸重氮苯四氟硼酸盐 | CAS号589-87-7 对溴碘苯 | CAS号380481-66-3 4-甲基苯硼酸新戊二醇酯 | CAS号624-31-7 对碘甲苯 | CAS号106-37-6 对二溴苯 | CAS号92-86-4 4,4-二溴联苯 | CAS号74-88-4 碘甲烷 | CAS号50670-50-3 4’-氰基-4-甲基联苯 | CAS号84337-86-0 [4-(4-bromophen... | CAS号5731-11-3 4'-溴[1,1'-联苯]-4-甲酸 | CAS号644-08-6 4-甲基联苯 | CAS号28952-41-2 1-methyl-4-(4-p... | CAS号97295-31-3 1,4-bis(4-methy... | CAS号50670-57-0 4'-溴-4溴甲基联苯

1-溴-4-[4-(三氟甲基)苯基]苯置于三乙基硅烷,四氯化钛体系中,用 1,2-二氯乙烷 作为反应溶剂,化学反应 0.5H,以83%的收率获得产物4-溴-4'-甲基联苯
参考文献:氢化钛催化四氯化钛催化加氢脱氟引发的三氟甲苯的转化
标题:氢化钛催化四氯化钛催化加氢脱氟引发的三氟甲苯的转化
摘要:以三乙基硅烷为还原剂,开发了四氯化钛催化的三氟甲苯衍生物的加氢脱氟反应.该反应通过容易获得的试剂产生了具有高化学选择性的各种甲苯衍生物.这种加氢脱氟过程已扩展到分子内friedel-Crafts苄基化反应,从而以非常好的收率提供了各种环大小的多环芳族化合物.
DOI:10.1002/adsc.201500920

专利信息

专利号:US-2010143980-A1
优先权日:2007-02-22
标题:Synthesis of novel xylosides and potential uses thereof
发明人：BALAGURUNATHAN KUBERAN; MANIVANNAN ETHIRAJAN; XYLOPHONE V VICTOR; TRAN VY MY; NGUYEN KHIEM
权利人:BALAGURUNATHAN KUBERAN; MANIVANNAN ETHIRAJAN; XYLOPHONE V VICTOR; TRAN VY MY; NGUYEN KHIEM
摘要:The present invention includes a xyloside for use in inducing synthesis of a glycosaminoglycan in a cell, the xyloside having a chemical structure of one of Formula (1), Formula (2), Formula (3), Formula (4), Formula (5), Formula (6), Formula (7), Formula (8), Formula (9), or Formula (10) as shown herein. Also, the present invention includes a method of making a xyloside for use in inducing synthesis of a glycosaminoglycan in a cell, wherein the method is performed with “Clickâ€? chemistry. Additionally, the present invention includes a method of administering a xyloside so as to induce synthesis of a glycosaminoglycan in a cell.

专利号:WO-2008103618-A1
优先权日:2007-02-22
标 题 :Synthesis of novel xylosides and potential uses thereof

专利号:US-8338565-B2
优先权日:2008-08-20
标 题 :Macrocyclic compounds for inhibition of tumor necrosis factor alpha
发明人：LEE JINBO; BOND JULIAN F; TERRETT NICHOLAS; FAVALORO JR FRANK G; WANG DANIEL; BRIGGS TIMOTHY F; SEIGAL BENJAMIN ADAM; SUN WEI-CHUAN; HALE STEPHEN P
权利人:LEE JINBO; BOND JULIAN F; TERRETT NICHOLAS; FAVALORO JR FRANK G; WANG DANIEL; BRIGGS TIMOTHY F; SEIGAL BENJAMIN ADAM; SUN WEI-CHUAN; HALE STEPHEN P; ENSEMBLE THERAPEUTICS CORP
摘要:Disclosed herein are macrocyclic compounds and methods for their synthesis and use. In particular, macrocyclic compounds are disclosed that modulate the activity of tumor necrosis factor alpha and/or are useful in the treatment of medical conditions, such as, rheumatoid arthritis, psoriasis, and asthma.

专利号:CN-114853642-A
优先权日:2022-04-27
标题:Synthesis method for directly alkylating benzyl position of aromatic compound