专利号:WO-2024199310-A1 优先权日:2023-03-31 标 题 :Method for enzymatic synthesis of capped mrna in one tube 发明人:LI YALI; ZHU HUAXING; ZHANG QINGYI 权利人:NOVOPROTEIN SCIENT INC 摘要:Provided is a method for enzymatic synthesis of capped mRNA in one tube. In the method, the step of purifying mRNA after IVT is omitted, and a capped product having a higher capping efficiency and fewer by-products is obtained. The method provided for enzymatic synthesis of capped mRNA is simple, convenient and short in terms of the process, and is rapid and efficient, so that the production process of a capped mRNA product is simplified, and a production cost is reduced, which is conducive to industrial production.
专利号:US-7122501-B2 优先权日:2000-06-01 标题:Catalyst and process for the direct synthesis of hydrogen peroxide 发明人:PAPARATTO GIUSEPPE; D ALOISIO RINO; DE ALBERTI GIORDANO; BUZZONI ROBERTO 权利人:ENICHEM SPA 摘要:A description follows of a bimetallic catalyst, obtained by dispersing in sequence and alternating the precursors of the single metal components of the catalyst on a carrier, and a process for the synthesis of hydrogen peroxide by the direct reaction of hydrogen with oxygen, in a solvent medium containing a halogenated promoter and an acid promoter, in the presence of said catalyst.
专利号:US-10150160-B2 优先权日:2014-12-04 标题 :Universal one-pot and up-scalable synthesis of SERS encoded nanoparticles 发明人:PAZOS PÉREZ NICOLÃ?S; MIR DE SIMÓN BERNAT 权利人:MEDCOM ADVANCE S A; MEDCOM ADVANCE S A 摘要:The universal one-pot and up-scalable synthesis of SERS encoded nanoparticles relies on the controlled co-absorption of mercaptoundecanoic acid (MUA) and the Raman code on the metallic surfaces of the nanoparticles. In contrast to most of the reported procedures which typically involve complex steps, the present method has demonstrated to be an easy and fast one-pot approach for the production of SERS-encoded nanoparticles. This versatile strategy allows for the SERS codification of particles with every molecule with affinity toward the metal surface, independently of its chemical nature, as exemplified here in the fabrication of 31 different encoded particles using the same standard procedure. In addition to the easiness of preparation, scalability to the liter regime, stability in aqueous solutions including PBS and chemical diversity, our SERS-encoded particles show considerably higher optical efficiency than those fabricated by using PEG or PVP polymers.
专利号:US-2023402618-A1 优先权日:2020-10-27 标 题:Method for synthesis of porous monoliths of transition-metal-doped-noble-metal 发明人:SINGH KIRANPAL; BHAT YASH RAJESH; CHARAYA HEMANT; CHAUDHARI VIJAY RAMAN 权利人:LOG 9 MATERIALS SCIENT PRIVATE LIMITED 摘要:The embodiment herein provides a simple, one-pot and scalable methodology for the synthesis of porous monoliths of Transition-metal-doped-noble-metal nanoparticles for cathode catalyst in a metal-air battery, PEMFCs, AFCs, and anode catalyst in water electrolysers. Silver is used as a base material on which doping is done with the transition metals selected from Cu, Co, Mn, Fe, and Ni.
专利号:US-10596632-B2 优先权日:2015-12-15 标题 :Method for the synthesis of metal nanoparticles in aqueous environment without the use of shape directing agents 发明人:MOGLIANETTI MAURO; POMPA PIER PAOLO 权利人:FONDAZIONE ST ITALIANO TECNOLOGIA 摘要:The present disclosure relates to a seed-growth based method for the synthesis of metal nanoparticles of controlled shape (cubes, cuboids, octahedrons) and size in an aqueous environment, without the use of shape directing agents. The method involves a first step of preparing a solution comprising water, metal seed growth nanoparticles, a metal salt comprising the same metal as the metal seed growth nanoparticles, and a reducing agent; and a second step of heating the solution to between 9 and 130° C. at a rate of between 1° C./min and 5° C./min and at a pressure of between 1 and 5 atm. The method may also be carried out in a reduced oxygen atmosphere and the concentration of oxygen disclosed in the solution may be less than the concentration of oxygen in an oxygen saturated solution.
专利号:US-9597327-B2 优先权日:2005-05-25 标 题:Synthesis of (R)-N-methylnaltrexone 发明人:DOSHAN HAROLD D; PEREZ JULIO 权利人:PROGENICS PHARM INC 摘要:This invention relates to stereoselective synthesis of R-MNTX and intermediates thereof, pharmaceutical preparations comprising R-MNTX or intermediates thereof and methods for their use.