1,6-己二醇,甲基丙烯酰氯置于4-二甲氨基吡啶,三乙胺体系中,用 二氯甲烷 作为反应溶剂,化学反应 3.0H,以39.5%的收率获得产物1,6-己二醇二甲基丙烯酸酯 参考文献:광반응 효율이 향상된 신규한 중합성 메조겐 화합물 및 이를 포함하는 중합성 액정 조성물 标题:광반응 효율이 향상된 신규한 중합성 메조겐 화합물 및 이를 포함하는 중합성 액정 조성물 摘要:本发明涉及一种利用光响应性基团引入α-氰基甲基丙烯酸酯基团以提高光响应效率的合成介质化合物及其包含的合成液晶组合物.本发明的合成介质化合物通过引入光响应性基团α-氰基甲基丙烯酸酯基团,在相对较低能量下具有提高的光响应效率,并且由于其不对称结构具有与主体液晶非常好的溶解性,同时还具有提高光交叉偏振角稳定性的效果,因此可以用作合成液晶组合物,特别适用于高分子稳定化背光型液晶显示器的合成液晶组合物.
专利号:WO-2024055132-A1 优先权日:2022-09-12 标 题 :Method for the synthesis of a branched copolymer of hyaluronic acid and poly(lactic-co-glycolic) acid 发明人:VILOS ORTIZ CRISTIAN ANDRÉS; ZACCONI FLAVIA CRISTINA MILAGRO; SALAZAR MUÑOZ JAVIER ALONSO 权利人:UNIV TALCA; UNIV PONTIFICIA CATOLICA CHILE; FUND CENTRO DE NANOCIENCIA Y NANOTECNOLOGIA 摘要:The present invention provides a method for the synthesis of a branched copolymer of hyaluronic acid (HA) and poly(lactic-co-glycolic acid) (PLGA), and the branched copolymer thus obtained (HA-g-PLGA). Said method comprises activating the PLGA with coupling reagents in a water miscible solvent; solubilizing the HA in a phosphate buffered saline solution; and adding the activated PLGA solution dropwise to the solution with HA to obtain the branched copolymer. The advantages of the present method are that it uses environmentally friendly conditions and allows the copolymer to be synthesized and purified in less than a week under laboratory conditions. In addition, the branched copolymer obtained does not present traces of any of the reagents used for its synthesis, so it can be used directly in the development of applications for human use.
专利号:US-5767211-A 优先权日:1996-05-02 标 题:Synthesis of multi-functional hyperbranched polymers by polymerization of di-or tri-vinyl monomers in the presence of a chain transfer catalyst 发明人:GUAN ZHIBIN 权利人:DU PONT 摘要:This invention concerns the synthesis of multi-functional hyperbranched polymers by free radical polymerization of di- or tri-vinyl monomers in the presence of a chain transfer catalyst and a non-peroxide free radical initiator. The low viscosity and high functionality of these polymers make them useful for automotive coatings and for photopolymerization applications.
专利号:US-2022233673-A1 优先权日:2019-06-04 标 题:METHODS OF PRODUCING SHIGA TOXIN B-SUBUNIT (STxB) MONOMERS AND OLIGOMERS, AND USES THEREOF 发明人:BILLET ANNE; SCHMIDT FRÉDÉRIC; JOHANNES LUDGER; SERVENT DENIS; MOURIER GILLES; TARTOUR ÉRIC; KAY MICHAEL; FULCHER JAMES M 权利人:INST CURIE; CENTRE NAT RECH SCIENT; INST NAT SANTE RECH MED; COMMISSARIAT A LENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES CEA; APHP ASSIST PUBLIQUE HOPITAUX DE PARIS; UNIV PARIS; UNIV OF UTAH RESEARCH FOUDATION; UNIV UTAH RES FOUND 摘要:A method of producing a monomer of a Shiga toxin B-subunit (STxB) protein or of a variant thereof by peptide chemical synthesis, as well as to a method of producing a pentamer of the STxB protein or of the variant thereof. The methods are particularly advantageous as they overcome major issues typically observed in peptide chemical synthesis, including solubility and purity issues.
专利号:WO-2024129887-A1 优先权日:2022-12-13 标题:Biobased synthesis of glucodiamine 发明人:MILLET AGUSTIN; WOELK HANS-JOERG; LEE TONI M; CHAKRABARTI GAURAB; HUNT SEAN 权利人:SOLUGEN INC 摘要:A method of preparing glucodiamine, comprising contacting glucose with an enzyme oxidation catalyst under conditions suitable for the formation of glucodialdose; contacting glucodialdose with a nitrogen-containing compound under conditions suitable for the formation of glucodioxime; and reducing glucodioxime under conditions suitable for the formation of glucodiamine. A method of preparing glucodiamine, comprising contacting glucodioxime with a dehydration catalyst under conditions suitable for the formation of glucodinitrile; and reducing glucodinitrile under conditions suitable for the formation of glucodiamine. A chemoenzymatic method of producing a bio-based amide platform chemical, comprising: contacting glucose with a biocatalyst under conditions suitable for the formation of glucodialdose; contacting glucodialdose with a base under conditions suitable for the formation of glucodioxime; and contacting glucodioxime with a hydrogenation catalyst in the presence of hydrogen under conditions suitable for formation of glucodiamine.
专利号:US-7728088-B2 优先权日:2002-08-06 标题 :Synthesis of statistical microgels by means of controlled radical polymerisation 发明人:DESTARAC MATHIAS; BAVOUZET BRUNO; TATON DANIEL 权利人:RHODIA OPERATIONS 摘要:The invention relates to a method of preparing statistical microgels. The inventive method comprises a step involving the radical polymerisation of a composition containing: at least one monoethylenically-unsaturated monomer, at least one multiethylenically-unsaturated monomer, a free radical source and a control agent. The invention also relates to first generation microgels thus prepared and all the compounds resulting from said microgels (next-generation microgels).
专利号:US-7763357-B2 优先权日:2005-01-27 标 题:Polymer composite synthesis in supercritical fluids 发明人:CHARPENTIER PAUL A; LI XINSHENG 权利人:CHARPENTIER PAUL A; LI XINSHENG 摘要:A one step synthetic route of polymeric compositions of a polyolefin and inorganic network consisting of components selected from Si, Zr, Ti, is disclosed. The synthetic route combines parallel reactions of free radical polymerization to form polymer, and hydrolysis of either Si, or Zr, or Ti or both of them precursors. The network consisting of Si, Zr, Ti, is chemically bonded to or within the polymer matrix. The inorganic or organic molecules can then be polymerized under conditions effective to cause the polymerized inorganic or organic molecules into macromolecular networks. The compositions of the polymeric composites can be easily controlled by adjusting the reactant ratio and reaction rate or conditions such as temperature and pressure, wherein the inorganic compositions disperse in nanoscale within polymeric composites when their concentrations fall below moderate levels. A novel synthesis route for making polymer composites and/or polymer nanocomposites of a polyolefin and an inorganic network consisting of components selected from Si, Zr, Ti, is disclosed. The synthesis route comprises hydrolysis of either Si, or Zr, or Ti alkoxides or mixtures of these precursors within a polymer matrix in supercritical fluids.
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