CAS: 19752-55-7; 1-Bromo-3,5-Dichlorobenzene

上下游产品

CAS号19393-97-6 2,5-DIBROMO-1,3... | CAS号697-86-9 2-溴-4,6-二氯苯胺 | CAS号554-00-7 2,4-二氯苯胺 | CAS号62720-30-3 5-溴-1,3-二氯-2-碘苯 | CAS号34883-41-5 3,5-二氯联苯 | CAS号2051-61-8 3-氯二苯酚 | CAS号41464-49-7 2,3,3'5'-四氯联苯 | CAS号54773-20-5 3,5-二氯三氟甲苯 | CAS号38444-88-1 3,4',5-三氯联苯 | CAS号3032-81-3 3,5-二氯碘苯 | CAS号541-73-1 间二氯苯 | CAS号82297-90-3 3,5-二氯苯溴化镁 | CAS号33284-52-5 3,3',5,5'-四氯联苯 | CAS号73575-52-7 2,3',4,5'-四氯联苯

(3,5-Dichlorophenyl)Hydrazine Hydrochloride置于三溴化硼,二甲基亚砜体系中,化学反应 1.0H,以97%的收率获得3,5-二氯-1-溴苯
参考文献:由芳基肼无金属和无碱合成芳基溴化物
标题:由芳基肼无金属和无碱合成芳基溴化物
摘要:通过在空气中于80oc在dmso / Cpme(环戊基甲基醚)中使用bbr 3,在不使用碱或金属催化剂的情况下,开发了一种从芳基肼盐酸盐合成溴化芳族化合物的有效方法.特别地,该方法可以使用吸电子基团令人满意地进行,以中等至优异的收率提供芳基溴化物.
Doi:10.1016/j.Tetlet.2020.151959

专利信息

专利号:WO-2022061917-A1
优先权日:2020-09-28
标题:Synthesis method for 3',5'-dichloro-2,2,2-trifluoroacetophenone
发明人：ZHANG LINGXIAO; CAI GANGHUA; TANG HONGYUAN; CHENG JINTAO
权利人:TAIZHOU ABSOBIOTEC CO LTD; ZHEJIANG JIANGBEI NANHAI PHARMACEUTICAL CO LTD
摘要:The present application relates to the technical field of chemical pharmaceutics, and in particular, to a synthesis method for 3',5'-dichloro-2,2,2-trifluoroacetophenone. The method comprises: first reacting 1,3,5-trichlorobenzene or 3,5-dichloro-1-bromobenzene with magnesium to form a Grignard reagent; and then subjecting the Grignard reagent and a trifluoroacetyl reagent to a nucleophilic addition reaction to obtain 3',5'-dichloro-2,2,2-trifluoroacetophenone after acid treatment. The synthesis method has mild reaction conditions, low raw material cost, favorable economic effect, and broad prospects for industrial production.

专利号:US-8853410-B2
优先权日:2009-04-30
标 题:Process for preparing substituted isoxazoline compounds and their precursors
发明人：RACK MICHAEL; KOERBER KARSTEN; KAISER FLORIAN
权利人:RACK MICHAEL; KOERBER KARSTEN; KAISER FLORIAN; BASF SE
摘要:The present invention relates to a new method of preparing halogenated styrene compounds of formula (VIII) n nwhich are precursors in the process of synthesis of substituted isoxazoline compounds of formula (I)n n nwherein R 1 to R 5 , R 8 and R 9 are described as in the description.n n The present invention relates further to the synthesis of compounds of formula (I) starting from acetophenones. The desired styrenes of formula are prepared from the appropriate substituted acetophenone. Asides bromo anilines react with formoxime. Obtained oximes undergo a cycloaddition with the styrenes and give isoxazolines. Compounds of formula (I) can then be prepared in a palladium catalyzed carbonylative amination reaction of the isoxazolines.

专利号:CN-116425623-A
优先权日:2023-04-10
标 题:Method for one-pot synthesis of 3,5-dichloro-4-methylbenzoic acid

专利号:JP-2009502923-A
优先权日:2005-07-26
标 题 :Method for the synthesis of substituted pyrazoles

专利号:CN-113024390-B
优先权日:2021-02-22
标 题:Synthesis method of 3’,5’-dichloro-2,2,2-trifluoroacetophenone derivatives

专利号:CN-119118784-A
优先权日:2024-09-04
标 题:Synthesis method of trifluoromethyl substituted aryl vinyl compound