CAS: 611-32-5; 8-Methylquinoline

上下游产品

CAS号56-81-5 甘油 | CAS号95-53-4 邻甲苯胺 | CAS号14002-34-7 三(3-羟基丙基)胺 | CAS号88-72-2 邻硝基甲苯 | CAS号52601-70-4 8-甲基-1,2,3,4-四氢喹啉 | CAS号156-87-6 3-氨基丙醇 | CAS号504-63-2 1,3-丙二醇 | CAS号78941-95-4 5-氯-8-甲基喹啉 | CAS号615-36-1 2-溴苯胺 | CAS号54304-36-8 8-methyl quinol... | CAS号112106-90-8 1,2,3,4-tetrahy... | CAS号38707-70-9 8-喹啉甲醛 | CAS号1445781-45-2 5-溴喹啉-8-羧酸甲酯 | CAS号19655-56-2 8-乙基喹啉 | CAS号78941-95-4 5-氯-8-甲基喹啉 | CAS号126145-72-0 5,7-dichloro-8-... | CAS号86-59-9 8-喹啉羧酸 | CAS号89942-59-6 2-乙酰基烟酸 | CAS号78941-93-2 7-氯-8-甲基喹啉 | CAS号89-00-9 吡啶-2,3-二羧酸

8-甲基喹啉1-氧化物置于二甲基二硫,Selectfluor体系中,用 乙腈 作为反应溶剂,以96 %的收率获得产物8-甲基喹啉
参考文献:Selectflu 和二硫烷对 N-杂环 N-氧化物进行脱氧
标题:Selectflu 和二硫烷对 N-杂环 N-氧化物进行脱氧
摘要:在此,我们描述了一种使用 Selectflu 与二硫烷进行 N-杂环 N-氧化物脱氧的无金属方法(33 个示例).这种有效,稳健且简单的方法能够在室温下从各种 N-杂环 N-氧化物核合成各种脱氧类似物,反应时间短,且产量定量.
DOI:10.1002/jhet.4818

专利信息

专利号:US-9506095-B2
优先权日:2012-02-09
标 题:Process for the enzymatic synthesis of (7S)-3,4-dimethoxybicyclo[4.2.0]octa-1,3,5-triene-7-carboxylic acid or esters thereof, and application in the synthesis of ivabradine and salts thereof
发明人：PEDRAGOSA-MOREAU SANDRINE; LEFOULON FRANÇOIS
权利人:SERVIER LAB; LES LABORATORIES SERVIER
摘要:Process for the enzymatic synthesis of the compound of formula (I): n nwherein R 1 represents a hydrogen atom or an alkyl group.n n Application in the synthesis of ivabradine and addition salts thereof with a pharmaceutically acceptable acid.

专利号:US-6479549-B2
优先权日:2000-02-28
标 题:Carnosic acid derivatives for promoting synthesis of nerve growth factor
发明人：KOSAKA KUNIO; MIYAZAKI TOSHITSUGU; YOKOI TOSHIO
权利人:NAGASE & CO LTD
摘要:A novel carnosic acid derivative for promoting the synthesis of nerve growth factor (NGF), a composition comprising the carnosic acid derivative as an effective ingredient, as well as, a method of promoting the synthesis of NGF comprising administering an effective amount of the carnosic acid derivative as an effective ingredient to a subject requiring such promotion. The carnosic acid derivative, composition and method according to the present invention can safely and efficiently promote the production of NGF in the living body, without being accompanied by a side effect such as a loss of a quantitative balance of hormones in the living body.

专利号:US-3732204-A
优先权日:1967-07-17
标题 :Synthesis of acronycine and related compounds
发明人：BECK J
权利人:LILLY CO ELI
摘要:THE TOTAL SYNTHESIS OF ACRONYCINIC AND RELATED COMPOUNDS FROM READILY AVAILABLE STARTING MATERIALS IS DESCRIBED, AS ARE VARIOUS CLASSES OF INTRMEDIATES USEFUL IN THE SYNTHESIS.

专利号:US-9000209-B2
优先权日:2011-07-22
标题:Method of regioselective synthesis of substituted benzoates
发明人：KRAUS GEORGE A
权利人:KRAUS GEORGE A; UNIV IOWA STATE RES FOUND INC
摘要:A method of synthesis of para-substituted benzoate esters and acids is provided, wherein the para-substituted regioisomer is obtained substantially free of the meta-substituted impurity, the method comprising contacting a coumalate ester or acid and an unactivated alkene at elevated temperature in the presence of a metal oxidation catalyst and an oxidant. The metal oxidation catalyst can be palladium, such as palladium on carbon, and the oxidant can be the oxygen gas in ambient air. The reaction can be carried out without solvent or in high boiling hydrocarbon solvents such as mesitylene. When the unactivated alkene is a monosubstituted alkene, yields of at least about 50 or 60% of para-substituted ester and acid products, respectively, are obtained, substantially free of the regioisomeric meta-substituted impurity.

专利号:US-8288581-B2
优先权日:2008-07-17
标 题:Process for the preparation of functionalised benzocyclobutenes, and application in the synthesis of ivabradine and addition salts thereof with a pharmaceutically acceptable acid
发明人：PEGLION JEAN-LOUIS; BAUDOIN OLIVIER; AUDIC NICOLAS; CHAUMONTET MANON; PICCARDI RICCARDO
权利人:PEGLION JEAN-LOUIS; BAUDOIN OLIVIER; AUDIC NICOLAS; CHAUMONTET MANON; PICCARDI RICCARDO; SERVIER LAB; CENTRE NAT RECH SCIENT
摘要:Process for the preparation of compounds of formula (IV): n nwherein R 1 -R 6 are as defined in the specification.n n Application in the synthesis of ivabradine, addition salts thereof with a pharmaceutically acceptable acid and hydrates thereof.

专利号:US-5859268-A
优先权日:1996-04-09
标 题:Process for the synthesis of α, β-unsaturated esters
发明人：ANGELICI ROBERT J; SHIH KUO-CHEN
权利人:UNIV IOWA STATE RES FOUND INC
摘要:The present invention provides a process for the synthesis of an α,β-unsaturated ester from a mono-olefin-ester using Fe(CO) 5 .