2,6-二氯吡啶置于溶剂黄146体系中,化学反应生成 2,6-二溴吡啶 参考文献:Process For The Manufacture Of Bromopyridines 标题:Process For The Manufacture Of Bromopyridines 摘要:揭示了一种新的制备2,4-二溴-,2,6-二溴-和2,4,6-三溴吡啶的新方法,以及由此获得的新溴吡啶.该新方法包括在无水有机介质中,以80度至130度之间的温度,用气态hbr处理2,4-二氯-,2,6-二氯-和2,4,6-三氯吡啶,该方法既简单又经济.
专利号:US-9755163-B2 优先权日:2010-04-30 标 题:Synthesis of four coordinated palladium complexes and their applications in light emitting devices thereof 发明人:LI JIAN; TURNER ERIC 权利人:ARIZONA BOARD OF REGENTS ACTING FOR AND ON BEHALF OF ARIZONA STATE UNIV; ARIZONA BOARD OF REGENTS ACTING FOR OR ON BEHALF OF ARIZONA STATE UNIV 摘要:Synthesis of four coordinated palladium complexes and their applications in light emitting devices thereof.
专利号:US-8569560-B2 优先权日:2006-10-13 标题 :Synthesis of terminal alkenes from internal alkenes via olefin metathesis 发明人:SCHRODI YANN; PEDERSON RICHARD L; KAIDO HIROKI; TUPY MICHAEL J 权利人:ELEVANCE RENEWABLE SCIENCES 摘要:This disclosure relates generally to olefin metathesis, and more particularly relates to the synthesis of terminal alkenes from internal alkenes using a cross-metathesis reaction catalyzed by an olefin metathesis catalyst. According to one aspect, for example, a method is provided for synthesizing a terminal olefin, the method comprising contacting, in the presence of a ruthenium alkylidene metathesis catalyst, an olefinic substrate comprised of at least one internal olefin with a cross metathesis partner comprised of an alpha olefinic reactant, under reaction conditions effective to allow cross-metathesis to occur, wherein the reaction conditions include a reaction temperature of at least 35° C. The methods, compositions, reactions and reaction systems herein disclosed have utility in the fields of catalysis, organic synthesis, and industrial chemistry.
专利号:US-9255117-B2 优先权日:2006-07-13 标题 :Synthesis of terminal alkenes from internal alkenes and ethylene via olefin metathesis 发明人:SCHRODI YANN 权利人:MATERIA INC 摘要:This invention relates generally to olefin metathesis, and more particularly relates to the synthesis of terminal alkenes from internal alkenes using a cross-metathesis reaction catalyzed by a selected olefin metathesis catalyst. In one embodiment of the invention, for example, a method is provided for synthesizing a terminal olefin, the method comprising contacting an olefinic substrate comprised of at least one internal olefin with ethylene, in the presence of a metathesis catalyst, wherein the catalyst is present in an amount that is less than about 1000 ppm relative to the olefinic substrate, and wherein the metathesis catalyst has the structure of formula (II) n nwherein the various substituents are as defined herein. The invention has utility, for example, in the fields of catalysis, organic synthesis, and industrial chemistry.
专利号:US-8697876-B2 优先权日:2010-04-02 标 题:Compositions and methods of synthesis of pyridinolypiperidine 5-HT1F agonists 发明人:CARNIAUX JEAN-FRANCOIS; CUMMINS JONATHAN 权利人:CARNIAUX JEAN-FRANCOIS; CUMMINS JONATHAN; COLUCID PHARMACEUTICALS INC 摘要:The present invention provides a novel polymorph of the hemisuccinate salt of 2,4,6-trifluoro-N-[6-(1-methyl-piperidine-4-carbonyl)-pyridin-2-yl]-benzamide (Form A) characterized by a unique X-ray diffraction pattern and Differential Scanning Calorimetry profile, as well as a unique crystalline structure. This polymorph is useful in pharmaceutical compositions, for example, for the treatment and prevention of migraine. The invention also provides a process for the synthesis of pyridinoylpiperidine compounds of Formula I in high yield and high purity. In particular, the provides a process for the preparation of 2,4,6-trifluoro-N-[6-(1-methyl-piperidine-4-carbonyl)-pyridin-2-yl]-benzamide, its hemisuccinate salt and polymorph (Form A).
专利号:US-9324957-B2 优先权日:2010-04-30 标 题:Synthesis of four coordinated gold complexes and their applications in light emitting devices thereof 发明人:LI JIAN; TUMER ERIC 权利人:LI JIAN; TUMER ERIC; UNIV ARIZONA STATE 摘要:Synthesis of four coordinated gold complexes and their applications in light emitting devices thereof.
专利号:US-5539117-A 优先权日:1993-04-13 标题:2-acetyl-6-cyanopyridines and their use as intermediates in the synthesis of oligo-2,6-pyridines 发明人:SNOW ROBERT A; DELECKI DANIEL J; SHAH CHANDRA R; HOLLISTER K ROBERT 摘要:The present invention is directed to 2-acetyl-6-cyanopyridine compounds that are useful as intermediates in the synthesis of oligo-2,6-pyridines. The present invention is also directed to new, simpler, less expensive methods for synthesizing such oligopyridines using the novel 2-acetyl-6-cyanopyridine compounds as intermediates.
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