CAS: 696-63-9; 4-Methoxythiophenol

上下游产品

p-methoxybenzenediazonium 4-methoxybenzenesulfinic acid methoxybenzene 4-methoxy-aniline 1-[(4-methoxy-phenylsulfanyl)-methyl]-piperidine (Z)-1,2-bis(p-methoxyphenylsulfanyl)ethylene trans-1,2-bis-(4-methoxy-phenylsulfanyl)-ethenetrans-1,2-bis-(4-methoxy-phenylsulfanyl)-ethene β-(4-methoxyphenylmercapto)propionic acid

4-碘苯甲醚置于copper(Ll) Sulfate Pentahydrate,1,2-乙二硫醇,Potassium Hydroxide体系中,用 水,二甲基亚砜 作为反应溶剂,化学反应 20.0H,以88%的收率获得产物4-甲氧基苯硫酚
参考文献:铜(II)催化由芳基卤化物和1,2-乙二硫醇合成芳基硫醇
标题:铜(II)催化由芳基卤化物和1,2-乙二硫醇合成芳基硫醇
摘要:利用铜(II)催化剂和1,2-乙二硫醇开发了一种高效的过渡金属催化的从芳基卤化物单步合成芳基硫醇的方法.关键特征是使用现成的试剂,简单的操作以及相对温和的反应条件.该新协议显示了广泛的底物范围,具有出色的官能团相容性.由芳基卤化物直接以高收率制备各种芳基硫醇.此外,芳基硫醇原位用于合成更高级的分子,例如二芳基硫醚和苯并噻吩.
DOI:10.1002/adsc.201400941

专利信息

专利号:US-6133409-A
优先权日:1996-12-19
标 题:Process for the solid phase synthesis of aldehyde, ketone, oxime, amine, hydroxamic acid and αβ-unsaturated carboxylic acid and aldehyde compounds
发明人：SALVINO JOSEPH M; MORTON GEORGE C; MASON HELEN J; LABAUDINIERE RICHARD F
权利人:AVENTIS PHARM PROD INC
摘要:This invention is directed to a process for the solid phase synthesis of aldehyde, ketone, oxime, amine, hydroxamic acid and alpha , beta -unsaturated carboxylic acid and aldehyde compounds and to polymeric hydroxylamine resin compounds useful therefor.

专利号:US-6710208-B2
优先权日:1996-12-19
标题 :Process for the solid phase synthesis of aldehyde, ketone, oxime, amine, hydroxamic acid and α,β-unsaturated carboxylic acid and aldehyde compounds
发明人：SALVINO JOSEPH M; MORTON GEORGE C; MASON HELEN J; LABAUDINIERE RICHARD F
权利人:AVENTIS PHARMA INC
摘要:This invention is directed to a process for the solid phase synthesis of aldehyde, ketone, oxime, amine, hydroxamic acid and α,β-unsaturated carboxylic acid and aldehyde compounds and to polymeric hydroxylamine resin compounds useful therefor.

专利号:US-11365211-B2
优先权日:2018-02-01
标 题 :Stereoselective synthesis and process for the manufacturing of 2′-deoxynucleosides
发明人：ZHANG LIANHAO; VISHNUVAJJALA BABURAO; MORRIS JOEL; BAHDE ROBERT; DENYSENKO SERGIY M; LOPEZ OMAR DIEGO; WISHKA DONN GREGORY
权利人:THE USA AS REPRESENTED BY THE SEC DEP OF HEALTH AND HUMAN SERVICES; ALCHEM LABORATORIES CORP; US HEALTH
摘要:Methods for stereoselective synthesis and manufacturing of 2′-deoxynucleosides, such as 2′-ribonucleosides, are disclosed. In some embodiments, the 2′-deoxynucleoside is a β-anomer of a 2′-deoxynucleoside having a 3′ α hydroxyl, 4′ β hydroxymethyl configuration. Nonlimiting examples of compounds prepared by the disclosed methods include 4′-thio-2′-deoxycytidine (T-dCyd) and 5-aza-4′-thio-2′-deoxycytidine (5-aza-T-dCyd; aza-T-dCyd; aza-T-dC).

专利号:US-7674881-B2
优先权日:2005-10-07
标题:Convergent synthesis of proteins by kinetically controlled ligation
发明人：KENT STEPHEN; PENTELUTE BRAD; BANG DUHEE; JOHNSON ERIK; DUREK THOMAS
权利人:UNIV CHICAGO
摘要:The present invention concerns methods and compositions for synthesizing a polypeptide using kinetically controlled reactions involving fragments of the polypeptide for a fully convergent process. In more specific embodiments, a ligation involves reacting a first peptide having a protected cysteyl group at its N-terminal and a phenylthioester at its C-terminal with a second peptide having a cysteine residue at its N-termini and a thioester at its C-termini to form a ligation product. Subsequent reactions may involve deprotecting the cysteyl group of the resulting ligation product and/or converting the thioester into a thiophenylester.

专利号:US-2016318862-A1
优先权日:2013-09-25
标 题:Synthesis of delta 12-pgj3 and related compounds
发明人：NICOLAOU KYRIACOS C; HERETSCH PHILIPP; HALE CHRISTOPHER R H; EL GHZAOUI ABDELLATIF EL MARROUNI; PULUKURI KIRAN KUMAR; YU RUOCHENG; GROVE CHARLES
权利人:UNIV RICE WILLIAM M
摘要:In one aspect, the present invention provides novel derivatives of Δ 12 -PGJ 3 and modular synthetic pathways to obtaining Δ 12 -PGJ 3 and derivatives thereof. In some aspects, the present derivatives of Δ 12 -PGJ 3 are useful as chemotherapeutic agents. The present disclosure also describes compositions of these derivatives as well as methods of use of the derivatives thereof.

专利号:US-5194562-A
优先权日:1989-02-22
标题:Nucleophilic displacement method for synthesis of non-rigid PBZ polymers
发明人：INBASEKARAN MUTHIAH N; MULLINS MICHAEL J
权利人:DOW CHEMICAL CO
摘要:Azole rings, such as oxazole and thiazole rings, can activate an aromatic ring bonded to a leaving group such as a halogen atom so that the aromatic ring will undergo aromatic nucleophilic substitution. The reaction is useful for making ethers, thioethers and amines containing azole rings. In particular, monomers having azole rings, activated aromatic rings with leaving groups and nucleophilic moieties can react under conditions of aromatic nucleophilic displacement to form non-rigid rob PBZ polymers. The non-rigid rod PBZ polymers can be used to form molecular composites with rigid rod PBZ polymers which molecular composites are not substantially phase separated.