CAS: 923032-59-1; 1-Allylcyclopropane-1-Sulfonyl Chloride
该化合物是一种有机化合物,其特点是存在环丙烷环,一个环基组和一个环氯功能组,其分子结构中含有三环丙烷环,有助于其独特的再活性和增殖;众所周知,该环丙烷组具有其电子生殖性,使该化合物在各种合成应用中有用,特别是在形成磺酰胺和其他衍生物方面;该环基组通过其双重联系提供额外的再活性,允许其可能参与各种化学反应,例如核生殖器替代或添加,该化合物的处理一般都是谨慎的,因为存在可与水进行腐蚀和反应的全氟氯化物协会,在水解中释放盐酸;
- 英文名称1-Allylcyclopropane-1-Sulfonyl Chloride
- 中文名称1-烯丙基环丙磺酰氯
- IUPAC名称1-allylcyclopropane-1-sulfonyl chloride
- 其它别名1-烯丙基环丙磺酰氯(Cas号:923032-59-1); 1-Prop-2-Enylcyclopropane-1-Sulfonyl Chloride
- CAS编号923032-59-1
- MFCD编号:MFCD11046295
- EINECS号:854-763-7
- 分子式:C6H9ClO2S
- 分子量:180.65
- 产品CID: 1960640
- 产品分类有机原料→分子砌块→脂肪环类化合物→环丙烷类化合物
相似化合物
30923-69-4 923032-55-7 2025076-89-3物理性质
MSDS等安全信息
欧盟法规
C&L通报合成工艺路线路线简述
- 923032-57-9 = 923032-59-1
反应条件:1.1 Reagents: Thionyl Chloride Catalysts: Dimethylformamide; 16 H,60 °C
标题:Preparation Of N-[2-(Arylamino)Aryl] Sulfonamide Compounds As Mek Kinase Inhibitors
参考文献:United States]
923032-57-9 = 923032-59-1
反应条件:1.1 Reagents: Thionyl Chloride Catalysts: Dimethylformamide; 16 H,60 °C
标题:Biomarkers For Determining Effective Response Of Treatments Of Hepatocellular Carcinoma Patients
参考文献:World Intellectual Property Organization]
923032-57-9 = 923032-59-1
反应条件:1.1 Reagents: Thionyl Chloride Catalysts: Dimethylformamide; 16 H,60 °C
标题:Preparation Of N-(Arylamino)-Sulfonamide Inhibitors Of Mek
参考文献:Brazil]
923032-57-9 = 923032-59-1
反应条件:1.1 Reagents: Thionyl Chloride Solvents: Dimethylformamide; 1.5 H,Reflux1.2 Reagents: Water
标题:Preparation Of N-Arylamino(Oxo)Pyridinyl Sulfonamides And N-Arylamino(Oxo)Pyrazinyl Sulfonamides As Mek Inhibitors And Useful In The Treatment Of Inflammatory Diseases,Cancer And Other Hyperproliferative Diseases
参考文献:World Intellectual Property Organization]
923032-57-9 = 923032-59-1
反应条件:1.1 Reagents: Thionyl Chloride Catalysts: Dimethylformamide; 16 H,60 °C
标题:Combinations Of Mek Inhibitors And Raf Kinase Inhibitors For Treatment And/or Prevention Of Cancer
参考文献:United States]
923032-57-9 = 923032-59-1
反应条件:1.1 Reagents: Thionyl Chloride Catalysts: Dimethylformamide; 16 H,60 °C
标题:Preparation Of Phenylaminophenylsulfonamides For Treatment Of Cancer And Inflammatory Disease.
参考文献:World Intellectual Property Organization]
923032-57-9 = 923032-59-1
反应条件:1.1 Reagents: Thionyl Chloride Catalysts: Dimethylformamide; 16 H,60 °C
标题:Combinations Of Mek Inhibitors And Raf Kinase Inhibitors And Uses Thereof
参考文献:World Intellectual Property Organization]
= 923032-59-1 [标题:Reaction Conditions
标题:Biomarkers For Determining Effective Response Of Treatments Of Hepatocellular Carcinoma (Hcc) Patients
参考文献:United States]
= 923032-59-1 [标题:Reaction Conditions
标题:Preparation Of N-(Arylamino)-Sulfonamide Inhibitors Of Mek
参考文献:United States
1-烯丙基环丙烷-1-磺酸丁酯置于氯化亚砜,Potassium Thioacyanate体系中,用 乙二醇二甲醚,水,N,N-二甲基甲酰胺 作为反应溶剂,化学反应 32.0H,反应生成 1-烯丙基环丙磺酰氯
参考文献: Biomarkers For Determining Effective Response Of Treatments Of Hepatocellular Carcinoma (Hcc) Patients[fr] Biomarqueurs Pour La Détermination De La Réponse Efficace De Traitements De Patients Atteints D'Un Carcinome Hépatocellulaire (Hcc)
标题: Biomarkers For Determining Effective Response Of Treatments Of Hepatocellular Carcinoma (Hcc) Patients[fr] Biomarqueurs Pour La Détermination De La Réponse Efficace De Traitements De Patients Atteints D'Un Carcinome Hépatocellulaire (Hcc)
摘要:本发明涉及使用一个或多个生物标志物,其定义为kras或nras基因,用于预测mek蛋白激酶抑制剂和/或sorafenib或regorafenib对肝细胞癌(hcc)患者的药物疗效或临床反应.此外,本发明还涉及用于识别hcc患者中突变型kras或nras基因的体外方法及其试剂盒.
海关参考信息
- 2901210000-乙烯
2901220000-丙烯 - 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
- 详情请参考：📖 海关编码查询和海关进出口税则
专利信息
专利号:US-9328066-B2
优先权日:2011-05-27
标 题 :Chiral synthesis of N-{3,4-difluoro-2-[(2-fluoro-4-iodophenyl)amino]-6-methoxyphenyl}-1-[2,3-dihydroxy-propyl]cyclopropanesulfonamides
发明人：FEY PETER; MAYER AGATHE CHRISTINE
权利人:FEY PETER; MAYER AGATHE CHRISTINE; BAYER IP GMBH
摘要:The present invention relates to a novel enantioselective method of preparing (S)- and (R)-enantiomers of N-{3,4-difluoro-2-[(2-fluoro-4-iodophenyl)amino]-6-5 methoxyphenyl}-1-[2,3-dihydroxy-propyl]cyclopropanesulfonamide, to novel intermediate compounds, and to the use of said novel intermediate compounds for the preparation of said (S)- and (R)-enantiomers of N-{3,4-difluoro-2-[(2-fluoro-4-iodophenyl)amino]-6-methoxyphenyl}-1-[2,3-dihydroxy-propyl]cyclopropanesulfonamide.
专利号:US-2014155637-A1
优先权日:2011-05-27
标题 :Chiral synthesis of n--1-[2,3-dihydroxy-propyl]cyclopropanesulfonamides
专利号:WO-2012163799-A1
优先权日:2011-05-27
标题 :Chiral synthesis of n-{3,4-difluoro-2-[(2-fluoro-4-iodophenyl)amino]-6-methoxyphenyl}-1-[2,3-dihydroxy-propyl]cyclopropanesulfonamides
专利号:EP-2714652-B1
优先权日:2011-05-27
标题:Chiral synthesis of n-{3,4-difluoro-2-[(2-fluoro-4-iodophenyl)amino]-6-methoxyphenyl}-1-[2,3-dihydroxy-propyl]cyclopropanesulfonamides
专利号:CN-119463191-B
优先权日:2025-01-16
标 题 :A kind of synthesis method of sulfurized methyl phenyl silicone rubber
专利号:CN-119463191-A
优先权日:2025-01-16
标题 :Synthesis method of room temperature vulcanized methyl phenyl silicone rubber
网址: http://www.huanlingchem.com
电话: 0519-89803565 13776850645👤
销售电话:0519-89803565 13776850645
邮箱：info4@huanlingchem.com
电话: 0519-89803565 13776850645👤
📞常州环灵化工有限公司 ⚠️参考联系方式
销售电话:0519-89803565 13776850645
邮箱：info4@huanlingchem.com
🆔 联系时候可告知是从"百琢研"平台获取的信息.
⚠️ 声明: 该企业未认证、未认领，请自行辨别信息的真实性和可靠性。咨询或交易时请注意风险评估与信息核实，百琢研不参与任何交易。企业认领注册入口→
⚠️ 未注册 · 未认证企业
备注: 📌 数据来源说明：本展台内容基于各搜索引擎等公开数据整理，仅作展示用途。请用户自行辨别 ✉️ 若企业需抹除展台内容或有异议， 请通过页面底部联系方式告知我们，我们会尽快处理。第 1 / 1 页
