专利号:US-2016073631-A1 优先权日:2013-03-04 标 题 :Process for the preparation of dihydropyrrole derivatives 发明人:EL QACEMI MYRIEM; SMITS HELMARS; CASSAYRE JEROME YVES; MULHOLLAND NICHOLAS PHILLIP; RENOLD PETER; GODINEAU EDOUARD; PITTERNA THOMAS 权利人:SYNGENTA PARTICIPATIONS AG; SYNGENTA LTD 摘要:The present invention provides stereoselective processes for the preparation of compounds of formula (I) n n n n n n n n n n n n wherein n P is phenyl, naphthyl, a 6-membered heteroaryl group containing one or two nitrogen atoms as ring members, or a 10-membered bicyclic heteroaryl group containing one or two nitrogen atoms as ring members, and wherein the phenyl, naphthyl and heteroaryl groups are optionally substituted; n R 1 is chlorodifluoromethyl or trifluoromethyl; n R 2 is optionally substituted aryl or optionally substituted heteroaryl; n n is 0 or 1; n including the process comprising n (a-i) reacting a compound of formula II n n n n n n n n n n n n n n n n wherein P, R 1 and R 2 are as defined for the compound of formula I; n with nitromethane in the presence a chiral catalyst to give a compound of formula III n n n n n n n n n n n n n n n n wherein P, R 1 and R 2 are as defined for the compound of formula I; and n (a-ii) reductively cyclising the compound of formula III to give the compound of formula I. n n n n n The invention also provides intermediates useful for processes for the synthesis of compounds of formula (I).
专利号:US-9968097-B2 优先权日:2012-05-30 标题:Composition comprising a biological control agent and a fungicide selected from inhibitors of the lipid membrane synthesis, the melanine biosynthesis, the nucleic acid synthesis or the signal transduction 发明人:WACHENDORFF-NEUMANN ULRIKE; ANDERSCH WOLFRAM; STENZEL KLAUS; SPRINGER BERND 权利人:BAYER CROPSCIENCE AG 摘要:The present invention relates to a composition comprising at least one biological control agent. Furthermore, the present invention relates to the use of this composition as well as a method for reducing overall damage of plants and plant parts.
专利号:US-2011230343-A1 优先权日:2008-10-24 标题 :Method for the Manufacture of Microparticles Comprising an Effect Substance 发明人:SCHROERS MICHAEL; DYLLICK-BRENZINGER RAINER; MERK MICHAEL; BARG HEIKO 权利人:BASF SE 摘要:A subject matter of the present invention is a process for the preparation of effect compound-comprising microparticles M comprising A) the formation of a crude suspension of microparticles A by means of enzymatic polyester synthesis in an inverse miniemulsion comprising enzyme, effect compound and polyester monomers; and B) the polymerization of wall monomers from the group consisting of ethylenically unsaturated monomers, polyisocyanates and polyepoxides in the crude suspension of microparticles A. Furthermore, the present invention relates to microparticles M which can be obtained by means of the process according to the invention and also to an agrochemical formulation comprising microparticles M. In addition, the present invention relates to the use of microparticles M prepared according to the invention as component in colorants, cosmetics, drugs, biocides, plant protection agents, fertilizers, additives for food or animal fodder, or auxiliaries for polymers, paper, textiles, leather, detergents or cleaners. Finally, the invention also relates to a method for combating undesirable plant growth, to a method for combating undesirable insect or acarid infestation on plants and/or for combating phytopathogenic fungi, and to seeds treated with the agrochemical formulation.
专利号:RU-2129788-C1 优先权日:1995-01-20 标题:Method of suppression of phytopathogen fungi, derivative of benzophenone, a method of protection of plants from damage caused by phytopathogen fungus, a fungicide composition, methods of synthesis of benzophenones
专利号:US-9706777-B2 优先权日:2012-05-30 标题:Composition comprising a biological control agent and a fungicide selected from inhibitors of amino acid or protein biosynthesis, inhibitors of ATP production and inhibitors of the cell wall synthesis 发明人:WACHENDORFF-NEUMANN ULRIKE; ANDERSCH WOLFRAM; STENZEL KLAUS; SPRINGER BERND 权利人:BAYER CROPSCIENCE AG 摘要:The present invention relates to a composition comprising at least one biological control agent. Furthermore, the present invention relates to the use of this composition as well as a method for reducing overall damage of plants and plant parts.
专利号:US-5684026-A 优先权日:1994-11-22 标 题:Aminocyclopentane derivative 发明人:OGAWA SEIICHIRO; UCHIDA CHIKARA; KIMURA HIROSHI; INOKUCHI JIN-ICHI 权利人:SEIKAGAKU KOGYO CO LTD 摘要:The present invention provides aminocyclopentane derivatives which are saccharide analogs having extremely high alpha -glucosidase inhibitory effects and novel structures and expected to be usable or applicable to drugs or agricultural chemicals. An aminocyclopentane derivative represented by the formula (1), wherein R1 represents H while R2 represents CH2OH, or R1 represents CH2OH while R2 represents H and R3 represents a substituted or unsubstituted aryl group or an alkyl, alkenyl, alkynyl or hydroxyalkyl group having 1 to 10 carbon atoms, intermediates for the synthesis of the same, a process for producing the intermediates and a process for producing the aminocyclopentane derivative.
1: Liu Y, Yang F, Wan S, Wang X, Guan L, Li Y, Xu C, Xie B, Wang S, Tan XL, Tang B. Comparative transcriptomic and metabolomics analysis of ovary in Nilaparvata lugens after trehalase inhibition. BMC Genomics. 2025 Feb 1;26(1):98. doi: 10.1186/s12864-025-11268-8. 2: Zhang H, Li H, Fang S, Guan D, Wei J, Wang Z, Luo Z, Qian K, Wang J. Co- application of Validamycin A and dsRNAs targeting trehalase genes conferred enhanced insecticidal activity against Laodelphax striatellus. Pestic Biochem Physiol. 2024 Nov;205:106160. doi: 10.1016/j.pestbp.2024.106160. Epub 2024 Oct 3. 81(2):903-911. doi: 10.1002/ps.8492. Epub 2024 Oct 22. 13(19):2743. doi: 10.3390/plants13192743. 5: Ogunnupebi TA, Oduselu GO, Elebiju OF, Ajani OO, Adebiyi E. In silico studies of benzothiazole derivatives as potential inhibitors of Anopheles funestus and Anopheles gambiae trehalase. Front Bioinform. 2024 Aug 9;4:1428539. doi: 10.3389/fbinf.2024.1428539.
合成参考文献
摘要:Japan Pesticide Information., (40)(32), 1982 摘要:Worthing, C.R. and S.B. Walker (eds.). The Pesticide Manual - A World Compendium. 8th ed. Thornton Heath, UK: The British Crop Protection Council, 1987., p. 836 摘要:Kirk-Othmer Encyclopedia of Chemical Technology. 3rd ed., Volumes 1-26. New York, NY: John Wiley and Sons, 1978-1984., p. V9 866 (1980) 摘要:Farm Chemicals Handbook 1992. Willoughby, OH: Meister Publishing Co., 1992., p. C355