CAS: 7252-84-8; 3-Amino-6-Methoxypyridazine

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1589503-98-9 39614-78-3 1173150-07-6

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CAS号5469-69-2 3-氨基-6-氯哒嗪 | CAS号124-41-4 甲醇钠 | CAS号127-75-3 4'-(6-methoxypy... | CAS号61471-99-6 6-methoxy-N-met... | CAS号64068-06-0 Imidazo[1,2-b]p...

磺胺甲氧哒嗪 以 水 作为反应溶剂,化学反应生成 3-氨基-6-甲氧基哒嗪
参考文献:水性介质中磺胺二甲嘧啶,磺胺甲氧基哌啶嗪,阿米替林和氯米帕明药物的光降解
标题:水性介质中磺胺二甲嘧啶,磺胺甲氧基哌啶嗪,阿米替林和氯米帕明药物的光降解
摘要:研究了两种抗菌磺胺类药物磺胺二甲嘧啶(smt)和磺胺甲氧基哒嗪(smp)以及两种三环抗抑郁药阿米替林(amt)和氯米帕明(cmp)的光化学转化.在人造阳光照射下在河水中进行的实验表明,与纯净水相比,Smt,Smp和cmp的降解加速了1.6-7.7倍.这种加速至少部分是由于在河水中可能发生的光敏反应.cmp的光降解特别快.另外,当发生光敏反应时,在纯水中没有观测到amt降解.在纯净水中在紫外线(254 Nm)照射下,四种药物被降解.计算的光降解量子产率为4.3x10-3,5.1x10-3,7.6x10-3,和65.0x10-3分别为smt,Smp,Amt,和cmp.uv与过氧化氢(uv / H2O 2)结合用作水污染的高级氧化工艺.与羟基自由基反应的计算出的二阶速率常数分别为5.0x10 9,5.0x10 9,8.0x10 9和9.5x10 9 大号摩尔-1 小号-1为smt,Sm
DOI:10.1016/j.Jphotochem.2016.12.008

专利信息

专利号:WO-2024256496-A1
优先权日:2023-06-14
标题 :[1,2,4]-triazolo[4,3-b]pyridazine derivatives useful as a medicament
发明人：ELIE JONATHAN; GEORGE PASCAL; MIEGE FRÉDÉRIC; MEIJER LAURENT
权利人:PERHA PHARMACEUTICALS
摘要:The present invention relates to a compound of formula (I) or any of its pharmaceutically acceptable salt. The present invention further relates to a synthesis process for manufacturing compound of formula (I) or any of its pharmaceutically acceptable salts, comprising at least a step of reacting a compound of formula (II) with an amine of formula (IV) NHR5R6 for example in a molar ratio ranging from 1 to 20 eq, with respect to the compound of formula (II), in an aprotic solvent or without solvent or else in a protic solvent.

专利号:CN-115594689-B
优先权日:2022-07-14
标题:A kind of relugoli intermediate and a kind of synthesis method of relugoli

专利号:CN-118271337-A
优先权日:2024-03-27
标 题:A synthesis process of relugoli