CAS: 89-39-4; 1,4-Dimethoxy-2-Nitrobenzene

• 英文名称1,4-Dimethoxy-2-Nitrobenzene
• 中文名称1,4-二甲氧基-2-硝基苯
• IUPAC名称1,4-dimethoxy-2-nitrobenzene
• 其它别名硝基二甲基氢醌; Benzene, 1,4-Dimethoxy-2-Nitro-
• CAS编号89-39-4
• MFCD编号:MFCD00024211
• EINECS号:201-903-4
• FDA UNII编号:26K58PSU0G
• 分子式:C8H9NO4
• 分子量:183.16
• 产品CID: 1915810
• 产品分类有机原料→分子砌块→芳环类化合物→苯类化合物

• 相似结构搜索
• InChIKey: UPTOWXNJLZJTGD-UHFFFAOYSA-N
• InChI=1S/C8H9NO4/c1-12-6-3-4-8(13-2)7(5-6)9(10)11/h3-5H,1-2H3…
• 计算化学: 氢键受体数4.0氢键供体数0.0可旋转键数3.0

物理性质

• 熔点72 °C
• 沸点169 °C at 13 mmHg
• 闪点156.7 °C
• 密度1.226g/cm3
• PSA:61.6
• LogP:1.612
• 折射率1.53
• 蒸汽压0.16Pa at 20°C
• 溶解性7.64e-04 M
• 外观形态白色至黄色至橙色粉末至晶体
• 储存条件储存在 室温

MSDS等安全信息

• GHS象形图
• GHS符号GHS07;
  注释: Exclamation mark
• 危险类别急性毒性 类别4(吸入)
  急性毒性 类别4(经皮)
  急性毒性 类别4(经口)
  水生慢性毒性 类别3
  严重眼刺激 类别2
• 警示词Warning(警告)
• 危险描述H332 |吸入有害.
  H312 |皮肤接触有害.
  H302 |吞咽有害.
  H412 |对水生生物有害并具有长期持续影响.
  H319 |造成严重眼刺激.
• 防范说明P264-P270-P273-P280-P330-P501

欧盟法规

上下游产品

合成工艺路线路线简述

• 150-78-7 = 89-39-4
  反应条件:1.1 Reagents: Methanesulfonic Anhydride,Phosphonium,Triphenyl(Phenylmethyl)-,Nitrate (1:1); 5 Min,Rt
  标题:A Fast And Mild Method For Nitration Of Aromatic Rings
  作者:Hajipour,Abdol R.; Ruoho,Arnold E.
  参考文献:Phosphorus 日期:2004 卷标:179(2) 页码:221-226]
  
  150-78-7 = 89-39-4
  反应条件:1.1 Reagents: Sodium Nitrite,Selectfluor Solvents: Acetonitrile
  标题:Novel Process For Generating Useful Electrophiles From Common Anions Using Selectfluor Fluorination Agent
  作者:Syvret,Robert G.; Butt,Kathleen M.; Nguyen,Tung P.; Bulleck,Victoria L.; Rieth,Ryan D.
  参考文献:Journal Of Organic Chemistry 日期:2002 卷标:67(13) 页码:4487-4493]
  
  150-78-7 = 89-39-4
  反应条件:1.1 Reagents: Nitric Acid Solvents: Acetic Acid,Water
  标题:Phenoxyquinones. Ii. The Diphenoxyquinones
  作者:Ungnade,Herbert E.; Zilch,Karl T.
  参考文献:Journal Of Organic Chemistry 日期:1951 卷标:16 页码:64-9]
  
  150-78-7 = 89-39-4
  反应条件:1.1 Reagents: Nitrogen Dioxide Solvents: Dichloromethane
  标题:A Mild One-Pot Procedure For The Polynitration Of Activated Arenes. Convenient Preparation Of Dinitro- And Trinitrodialkoxybenzenes
  作者:Nose,Masatoshi; Suzuki,Hitomi
  参考文献:Synthesis 日期:2000 卷标:(11) 页码:1539-1542]
  
  150-78-7 = 89-39-4
  反应条件:1.1 Reagents: Nitric Acid Solvents: Acetic Acid,Dichloromethane; 2 H,0 °C
  标题:Hydrogen Bonded Arylamide-Linked Cholesteryl Dimesogenic Liquid Crystals: A Study Of The Length And Side Chain Effects
  作者:Wang,Gui-Tao; Zhao,Xin; Li,Zhan-Ting
  参考文献:Tetrahedron 日期:2011 卷标:67(1) 页码:48-57]
  
  150-78-7 = 89-39-4
  反应条件:1.1 Reagents: Cupric Nitrate; 30 Min,70 - 80 °C
  标题:Zeolite H-Y-Supported Copper(Ii) Nitrate. A Simple And Effective Solid-Supported Reagent For Nitration Of Phenols And Their Derivatives
  作者:Lalitha,A.; Sivakumar,K.
  参考文献:Synthetic Communications 日期:2008 卷标:38(11) 页码:1745-1752]
  
  150-78-7 = 89-39-4
  反应条件:1.1 Reagents: Phosphorus Pentoxide,Silica; 30 S,Rt1.2 Reagents: Nitric Acid; 3 Min,Rt
  标题:Nitric Acid In The Presence Of P2O5 Supported On Silica Gel - A Useful Reagent For Nitration Of Aromatic Compounds Under Solvent-Free Conditions
  作者:Hajipour,Abdol Reza; Ruoho,Arnold E.
  参考文献:Tetrahedron Letters 日期:2005 卷标:46(48) 页码:8307-8310]
  
  150-78-7 = 89-39-4
  反应条件:1.1 Reagents: Manganese Oxide (Mno2),Nitric Acid Solvents: Diethyl Ether
  标题:Studies On Quinones. Part 16. An Improved Method For Releasing Quinones From Hydroquinone Dimethyl Ethers With Acid-Impregnated Manganese Dioxide Under Ultrasonic Irradiation
  作者:Araya,Ramiro; Tapia,Ricardo; Valderrama,Jaime A.
  参考文献:Journal Of Chemical Research 日期:1987 卷标:(3) 页码:84-5]
  
  150-78-7 = 89-39-4
  反应条件:1.1 Solvents: Acetonitrile
  标题:Aromatic Nitration With Ion Radical Pairs [arh.+,No2.] As Reactive Intermediates. Time-Resolved Studies Of Charge-Transfer Activation Of Dialkoxybenzenes
  作者:Sankararaman,S.; Haney,W. A.; Kochi,Jay K.
  参考文献:Journal Of The American Chemical Society 日期:1987 卷标:109(17) 页码:5235-49]
  
  150-78-7 = 89-39-4
  反应条件:1.1 Reagents: Chlorotrimethylsilane,Guanidine Nitrate Catalysts: Copper Sulfate Solvents: Acetonitrile; 4 H,Rt
  标题:Acid-Free Copper-Catalyzed Electrophilic Nitration Of Electron-Rich Arenes With Guanidine Nitrate
  作者:Li,Wen-Pei; Cheng,Guo; Li,Si-Yuan; Lin,Cheng-Zhou; Guan,Xiao-Yu; Et Al
  参考文献:Journal Of Organic Chemistry 日期:2022 卷标:87(5) 页码:3834-3840]
  
  150-78-7 = 89-39-4
  反应条件:1.1 Reagents: Tert-Butyl Nitrite Solvents: Dichloromethane; 6 H,Rt
  标题:Metal-Free Transformations Of Nitrogen-Oxyanions To Ammonia Via Oxoammonium Salt
  作者:Sahana,Tuhin; Mondal,Aditesh; Anju,Balakrishnan S.; Kundu,Subrata
  参考文献:Angewandte Chemie 日期:2021 卷标:60(38) 页码:20661-20665]
  
  150-78-7 = 89-39-4
  反应条件:1.1 Reagents: Oxygen,2407717-84-2; 2 H,25 °C
  标题:3-(Ethoxycarbonyl)-1-(5-Methyl-5-(Nitrosooxy)Hexyl)Pyridin-1-Ium Cation: A Green Alternative To Tert-Butyl Nitrite For Synthesis Of Nitro-Group-Containing Arenes And Drugs At Room Temperature
  作者:Natarajan,Palani; Chaudhary,Renu; Rani,Neetu; Sakshi; Venugopalan,Paloth
  参考文献:Tetrahedron Letters 日期:2020 卷标:61(9)]
  
  150-78-7 = 89-39-4
  反应条件:1.1 Reagents: Ferric Nitrate Solvents: Acetonitrile; 10 Min,Rt; 40 Min,Rt
  标题:Electron-Driven Nitration Of Unsaturated Hydrocarbons
  作者:Patra,Subrata; Mosiagin,Ivan; Giri,Rahul; Nauser,Thomas; Katayev,Dmitry
  参考文献:Angewandte Chemie 日期:2023 卷标:62(28)]
  
  150-78-7 = 89-39-4
  反应条件:1.1 Reagents: Nitric Acid
  标题:Azo Pigment Derivatives Of 4-(Alkylaminosulfonyl)-2,5-Dimethoxyaniline
  作者:Sebe,Ion; Floru,Lucian; Ionescu,Dumitru; Vladescu,Constantin
  参考文献:Revistade Chimie (Bucharest 日期:1983 卷标:34(5) 页码:398-402]
  
  150-78-7 = 89-39-4
  反应条件:1.1 Reagents: Nitric Acid,Ammonium Cerium(3+) Salt (5:2:1),Tetrahydrate Solvents: Acetic Anhydride; 14 H,25 °C
  标题:A Mild And Efficient Method For The Mononitration Of Aromatic Compounds By Cerium(Iii) Ammonium Nitrate In Acetic Anhydride
  作者:Tanemura,Kiyoshi; Suzuki,Tsuneo; Nishida,Yoko; Satsumabayashi,Koko; Horaguchi,Takaaki
  参考文献:Journal Of Chemical Research 日期:2003 卷标:(8) 页码:497-499]
  
  150-78-7 = 89-39-4
  反应条件:1.1 Reagents: Cupric Nitrate Solvents: Diethyl Ether,Acetic Anhydride
  标题:The Nitration Of Electron-Rich Aromatics
  作者:Dwyer,C. L.; Holzapfel,C. W.
  参考文献:Tetrahedron 日期:1998 卷标:54(27) 页码:7843-7848]
  
  150-78-7 = 89-39-4
  反应条件:1.1 Reagents: Nitric Acid Solvents: Water
  标题:Improved Technology For Synthesis Of 2,5-Dimethoxybenzenamine
  作者:Cai,Chun; Lu,Chunxu
  参考文献:Ranliao Gongye 日期:2000 卷标:37(2) 页码:14-15

海关参考信息

• 2905110000-甲醇
  2908991010-4-硝基苯酚
  2908199090-其他酚的卤化衍生物
  2918290000-其他含酚基羧酸
• 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
• 详情请参考：📖 海关编码查询和海关进出口税则

专利信息

其他信息查阅

• ➥ 象形图和危险代码
• ➥ 防范代码详解
• ➥ 危险代码说明
• ➥ Globally Harmonized System
• ➥ REACH监管