专利号:US-5998620-A 优先权日:1997-03-25 标 题 :Synthesis of intermediates useful in preparing tricyclic compounds 发明人:CHEN XING; POIRIER MARC; WONG YEE-SHING; WU GUANG-ZHONG 权利人:SCHERING CORP 摘要:The invention relates to a process for preparing a compound of the formula ##STR1## comprising reacting a bromo-substituted pyridine with an amine of the formula NHR 5 R 6 , reacting the resulting amide with an iodo-halomethyl-substituted compound and cyclizing the resultant product, wherein R, R 1 , R 2 , R 3 and R 4 are as defined in the specification; also claimed are a compound of the formula ##STR2## and a process for preparing it from the corresponding halo-substituted benzoic acid.
专利号:EP-0977739-B1 优先权日:1997-03-25 标题 :Synthesis of intermediates useful in preparing tricyclic compounds 发明人:CHEN XING; POIRIER MARC; WONG YEE-SHING; WU GUANG-ZHONG 权利人:SCHERING CORP 摘要:The invention relates to a process for preparing a compound of formula (I), comprising reacting a bromo-substituted pyridine with an amine of the formula NHR5R6, reacting the resulting amide with an iodo-halomethyl-substituted compound and cyclizing the resultant product, wherein R, R?1, R2, R3 and R4¿ are as defined in the specification; also claimed are a compound of formula (a), and a process for preparing it from the corresponding halo-substituted benzoic acid.
专利号:CA-2284646-C 优先权日:1997-03-25 标 题 :Synthesis of intermediates useful in preparing tricyclic compounds
专利号:DE-69819316-T2 优先权日:1997-03-25 标题:SYNTHESIS OF INTERMEDIATE PRODUCTS APPLICABLE IN THE PRODUCTION OF TRICYCLIC COMPOUNDS
专利号:WO-9842676-A1 优先权日:1997-03-25 标 题:Synthesis of intermediates useful in preparing tricyclic compounds
专利号:EP-0977739-A1 优先权日:1997-03-25 标题 :Synthesis of intermediates useful in preparing tricyclic compounds
摘要:Hay, M. B.; Hicks, J. D., Science of Synthesis: Cross Coupling and Heck-Type Reactions, (2012) 2, 154. 摘要:Sanford, M. S.; Cook, A., Science of Synthesis: Catalytic Transformations via CH Activation, (2015) 2, 212.