专利号:WO-2012001578-A1 优先权日:2010-06-29 标 题 :Single-step synthesis of iron oxide nanoparticles 发明人:BURDINSKI DIRK; HAEX NICOLE PETRONELLA MARTIEN 权利人:KONINKL PHILIPS ELECTRONICS NV; BURDINSKI DIRK; HAEX NICOLE PETRONELLA MARTIEN 摘要:The invention provides methods for the synthesis of iron oxide nanoparticles and the particles obtainable by these methods. The particles can be used as tracer materials for magnetic particle imaging and for Magnetic Particle Spectroscopy (MPS). The method for the synthesis of these particles comprises the steps: (i) dissolving at least one water-soluble iron salt and at least one water-soluble stabilizer in water to form a reaction batch, (ii) adding at least one base to the reaction batch to yield a pH of 10 to 13, and (iii) exposing the reaction batch to a reaction temperature T R for a defined period of time DT, wherein T R ≥ 110°C, to obtain the iron oxide nanoparticles.
专利号:WO-2009117718-A1 优先权日:2008-03-20 标 题:Direct chemical synthesis of rare earth-transition metal alloy magnetic materials 发明人:CHINNASAMY C N; HARRIS VINCENT G 权利人:UNIV NORTHEASTERN; CHINNASAMY C N; HARRIS VINCENT G 摘要:A direct chemical synthesis scheme for the fabrication of isotropic and anisotropic rare earth (RE) -transition metal (TM)- based permanent magnets is disclosed. The method according to the invention permits the synthesis of, e.g., particles, films and coatings with controlled particle sizes, shapes, compositions and dispersion in one reaction process. The resulting particles have desirable hard magnetic properties such as high magnetic saturation induction and coercivity at room temperature.
专利号:US-2018297857-A1 优先权日:2015-06-02 标 题:Aqueous Synthesis of Polyhedral 'Brick-Like' Iron Oxide Nanoparticles for Hyperthermia and T2 MRI Contrast Enhancement, and for Targeting Endothelial Cells for Therapeutic Delivery 发明人:HEGMANN TORSTEN; WORDEN MATTHEW; MILLER DONALD W 权利人:UNIV KENT STATE OHIO 摘要:A low temperature, aqueous synthesis of polyhedral iron oxide nanoparticles (IONPs) is presented. The modification of the co-precipitation hydrolysis method with Triton X surfactants results in the formation of crystalline polyhedral particles. The particles are herein termed iron oxide “nanobricks†(IONBs), as the varieties of particles made are all variations on a simple “brick-like†, polyhedral shape such as rhombohedral shape or parallelogram as evaluated by TEM. These IONBs can be easily coated with hydrophilic silane ligands, allowing them to be dispersed in aqueous media. The dispersed particles are investigated for potential applications as hyperthermia and T 2 MRI contrast agents. The results demonstrate that the IONBs perform better than comparable spherical IONPs in both applications, and show r 2 values amongst the highest for iron oxide based materials reported in the literature.
专利号:US-2020030462-A1 优先权日:2018-07-24 标 题 :GREEN SYNTHESIS OF BIOCOMPATIBLE AND NEAR INFRARED ACTIVE EUGENATE (4-allyl-2-methoxyphenolate) CAPPED IRON OXIDE NANOPARTICLES FOR DEEP TISSUE IMAGING AND THERAPY 发明人:SHARAD GUPTA; PRASHANT KHAREY 权利人:INDIAN INSTITUTE OF TECH INDORE 摘要:NIR active, biocompatible and multifunctional (magnetic, photo-acoustic, and photo-thermal agent) E-capped iron oxide nanoparticles for deep tissue imaging and cancer therapy, are synthesized by a simple, rapid, non-toxic, low-cost and efficient completely green synthesis technique using extract made from the leaves of a medicinal aromatic plant, Pimenta dioica.
专利号:US-5262176-A 优先权日:1986-07-03 标题:Synthesis of polysaccharide covered superparamagnetic oxide colloids 发明人:PALMACCI STEPHEN; JOSEPHSON LEE 权利人:ADVANCED MAGNETICS INC 摘要:In a method for the synthesis of a colloid including a superparamagnetic metal oxide coated with a polymer, an acidic solution of a metal salt and a polymer may be cooled, and then neutralized by the controlled addition of a cool solution of a base, and may then be converted, by the application of heat, to a homogenous superparamagnetic metal oxide colloid. According to a preferred embodiment, the polymer may be a polysaccharide. In a further embodiment of the invention, the polysaccharide may be dextran and the metal salt may be ferrous and ferric salts, which produces, according to the methods of the invention, a superparamagnetic iron oxide colloid with an extended plasma half-life.
专利号:US-11739112-B2 优先权日:2017-02-02 标 题:Low temperature process for the synthesis of MOF carboxylate nanoparticles 发明人:PANCHAL MONIK; NOUAR FARID; SERRE CHRISTIAN; BENZAQUI MARVIN; SENE SAAD; STEUNOU NATHALIE; GIMÉNEZ MARQUÉS MONICA 权利人:CENTRE NAT RECH SCIENT; UNIV DE VERSAILLES—SAINT QUENTIN EN YVELINES 摘要:The present invention relates to low temperature process for preparing nanoparticles of porous crystalline Fe-, Al- or Ti-based MOF carboxylate materials with low polydispersity index, and uses thereof, particularly as catalyst support for carrying out heterogeneously catalyzed chemical reactions, or as gas storage/separation/purification material, or as matrix for encapsulating active principles (medicine, cosmetics).
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