CAS: 214360-51-7; 4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-yl)Benzenesulfonamide

上下游产品

4-bromo-benzenesulfonic acid amide bis(pinacol)diborane sulfanilamide 2,3-dimethyl-2,3-butane diol valdecoxib 4-(6-bromoimidazo[1,2-a]pyridin-3-yl)-1-benzenesulfonamide N-Cyclopropyl-1-[3-(4-sulfamoylphenyl)phenyl]-1,4-dihydro[1,8]naphthyridin-4-one-3-carboxamide 4-(aminosulfonyl)-4-chloro-4'-(methyloxy)-1,1':3',1-terphenyl-5'-carboxamide

4-溴苯磺酰胺置于(1,1'-Bis(Diphenylphosphino)Ferrocene)Palladium(II) Dichloride,Potassium Acetate体系中,用 乙醇 用作溶剂,化学反应 2.5H,反应生成苯基磺酰胺-4-硼酸
参考文献:Syntheses Of (4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-yl)Arenes Through Pd-Catalyzed Borylation Of Arylbromides With The Successive Use Of 2,2'-Bis(1,3,2-Benzodioxaborole) And Pinacol
标题:Syntheses Of (4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-yl)Arenes Through Pd-Catalyzed Borylation Of Arylbromides With The Successive Use Of 2,2'-Bis(1,3,2-Benzodioxaborole) And Pinacol
摘要:Syntheses Of (4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-yl)Arenes Through The Pd-Catalyzed Borylation Of Arylbromides With The Successive Use Of 2,2'-Bis(1,3,2-Benzodioxaborole) And Pinacol Were Investigated. Pdcl2(Dppf) And Acok In Etoh Or Dmso Successfully Provided (4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-yl)Arenes. In Particular,This Method Was More Effective In The Borylation Of Arylbromides Bearing Sulfonyl Groups Than The Conventional Pd-Catalyzed Borylation Using Pinacolborane Or Bis(Pinacolato)Diboron. (C) 2012 Elsevier Ltd. All Rights Reserved.
Doi:10.1016/j.Tetlet.2012.10.118

专利信息

专利号:US-2007275968-A1
优先权日:2004-09-07
标 题 :Substituted Biphenyl Derivative
发明人：KURATA HITOSHI; NISHIMATA TOYOKI; WATANABE YUKIKO; EBISAWA MASAYUKI; FUJIMOTO TEPPEI; KOBAYASHI HIDEKI
权利人:KURATA HITOSHI; NISHIMATA TOYOKI; WATANABE YUKIKO; EBISAWA MASAYUKI; FUJIMOTO TEPPEI; KOBAYASHI HIDEKI
摘要:The present invention relates to a biaryl derivative or a pharmacologically acceptable salt thereof having an excellent collagen-synthesis inhibition activity. A biaryl derivative having a structure represented by the following General Formula (I) or a pharmacologically acceptable salt thereof: n nwherein n R 1 represents a C 6 -C 10 aryl group which is substituted with one to three group(s) each independently selected from the group consisting of a group defined by formula R-L-, a di-(C 1 -C 6 alkyl)amino group, a di-(C 1 -C 6 alkyl)aminosulfonyl group, a hydroxyaminocarbonyl group, and a halogen atom, and so on; R represents a C 1 -C 6 alkyl group, and so on; L represents a sulfonyl group, an aminosulfonyl group, or a sulfonylamino group, and so on; R 2 represents a hydrogen atom, and so on; A represents a group defined by formula (II), (III), or (IV); R 3 represents a C 1 -C 6 alkyl group, and so on; and R 4 represents a C 1 -C 6 alkyl group, and so on.

专利号:US-7541367-B2
优先权日:2005-05-31
标 题 :3-benzoimidazolyl-pyrazolopyridines useful in treating kinase disorders
发明人：CHIU GEORGE; CONNOLLY PETER J; EMANUEL STUART; HUANG SHENLIN; LI SHENGJIAN; LIN RONGHUI; LU YANHUA; MIDDLETON STEVEN A
权利人:JANSSEN PHARMACEUTICA NV
摘要:The present invention is directed to novel 3-benzoimidazolyl-pyrazolopyridine compounds of formula (I): n nand pharmaceutically acceptable forms thereof and their synthesis and use as inhibitors of serine-threonine protein kinases and tyrosine protein kinases and interactions thereof.