CAS: 364794-79-6; 4-(4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-yl)Benzyl)Morpholine

上下游产品

4-(羟甲基)苯硼酸频哪醇酯 (4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-yl)Phenyl)Methanol 302348-51-2
4-溴甲基苯硼酸频哪醇酯 4-Bromomethylphenylboronic Acid Pinacol Ester 138500-85-3

4-羟甲基苯硼酸置于[ruthenium(II)(η6-1-Methyl-4-Isopropyl-Benzene)(Chloride)(μ-Chloride)]2,Sodium Carbonate,双(2-二苯基磷苯基)醚体系中,用 5,5-Dimethyl-1,3-Cyclohexadiene,甲苯 作为反应溶剂,化学反应 26.0H,反应生成 4-(4-吗啉甲基)苯硼酸频哪酯
参考文献:Synthesis Of Amines With Pendant Boronic Esters By Borrowing Hydrogen Catalysis
标题:Synthesis Of Amines With Pendant Boronic Esters By Borrowing Hydrogen Catalysis
摘要:Amine Alkylation Reactions Of Alcohols Have Been Performed In The Presence Of Boronic Ester Groups To Provide Products Which Are Known To Have Use As Molecular Sensors. The Boronic Ester Moiety Could Be Present In Either The Alcohol Or Amine Starting Material And Was Not Compromised In The Presence Of A Ruthenium Catalyst.
DOI:10.1021/ol402271A

专利信息

专利号:US-2007275968-A1
优先权日:2004-09-07
标 题 :Substituted Biphenyl Derivative
发明人：KURATA HITOSHI; NISHIMATA TOYOKI; WATANABE YUKIKO; EBISAWA MASAYUKI; FUJIMOTO TEPPEI; KOBAYASHI HIDEKI
权利人:KURATA HITOSHI; NISHIMATA TOYOKI; WATANABE YUKIKO; EBISAWA MASAYUKI; FUJIMOTO TEPPEI; KOBAYASHI HIDEKI
摘要:The present invention relates to a biaryl derivative or a pharmacologically acceptable salt thereof having an excellent collagen-synthesis inhibition activity. A biaryl derivative having a structure represented by the following General Formula (I) or a pharmacologically acceptable salt thereof: n nwherein n R 1 represents a C 6 -C 10 aryl group which is substituted with one to three group(s) each independently selected from the group consisting of a group defined by formula R-L-, a di-(C 1 -C 6 alkyl)amino group, a di-(C 1 -C 6 alkyl)aminosulfonyl group, a hydroxyaminocarbonyl group, and a halogen atom, and so on; R represents a C 1 -C 6 alkyl group, and so on; L represents a sulfonyl group, an aminosulfonyl group, or a sulfonylamino group, and so on; R 2 represents a hydrogen atom, and so on; A represents a group defined by formula (II), (III), or (IV); R 3 represents a C 1 -C 6 alkyl group, and so on; and R 4 represents a C 1 -C 6 alkyl group, and so on.