CAS: 47465-97-4; 3,3-Bis(4-Hydroxy-3-Methylphenyl)Indolin-2-One

该化合物是化学化合物,主要用作有机合成和制药应用的中间体.其分子结构以异丁和硅酸盐为主,具有独特的反应性,对建造异环化合物和活性药物成分(APIs)很有价值.该化合物在标准条件下具有稳定性,并表明与一系列试剂相容性,为多种合成途径提供了便利.其双功能性质允许有选择的修改,能够对复杂反应进行精确控制.Istatin Bis-cressols因其在生产高纯度中间体,促进药用化学和特殊化学制造的高效和可扩展过程方面所发挥的作用而特别突出.

结构式图片

上下游产品

3,3-dichloro-2,3-dihydro-1H-indol-2-one ortho-cresol indole-2,3-dione

合成工艺路线路线简述

    3,3-Dichloroindolin-2-One,邻甲酚 反应生成 靛红联二甲酚
    参考文献:Inagaki,Yakugaku Zasshi/journal Of The Pharmaceutical Society Of Japan,1933,Vol. 53,P. 686,696;Dtsch.Ref.S.133
    标题:Inagaki,Yakugaku Zasshi/journal Of The Pharmaceutical Society Of Japan,1933,Vol. 53,P. 686,696;Dtsch.Ref.S.133

    海关参考信息

    专利信息


    专利号:US-8394912-B2
    优先权日:2009-12-22
    标 题 :Process and apparatus for the preparation of polycarbonate
    发明人:DOEBERT FRANK; STREMMEL ANDREAS; BIEDRON CHRISTOPH; LAUE STEPHAN; RECHNER JOHANN; HAGEN TORSTEN; BRUYNSEELS FRANK; QUAEYHAEGENS FRANK; DECLOEDT JOHAN; VAN DORST PAUL; ARNDT UWE; EYNDE JOHAN VANDEN; TRACHT URSULA; KOENIG THOMAS; LIESENFELDER ULRICH
    权利人:DOEBERT FRANK; STREMMEL ANDREAS; BIEDRON CHRISTOPH; LAUE STEPHAN; RECHNER JOHANN; HAGEN TORSTEN; BRUYNSEELS FRANK; QUAEYHAEGENS FRANK; DECLOEDT JOHAN; VAN DORST PAUL; ARNDT UWE; EYNDE JOHAN VANDEN; TRACHT URSULA; KOENIG THOMAS; LIESENFELDER ULRICH; BAYER MATERIALSCIENCE AG
    摘要:The invention relates to a process for the pretreatment of material surfaces in order to minimize the interaction between polycarbonate and metal and, in the processing and synthesis of polycarbonate, to obtain a high-quality polymer which in particular does not become discolored and is free of insoluble constituents.

    专利号:US-6596840-B1
    优先权日:1999-07-19
    标题 :Method for producing modified polycarbonates
    发明人:KRATSCHMER SILKE; HUCKS UWE; BUNZEL LOTHAR
    权利人:BAYER AG
    摘要:A process for the synthesis of polycarbonate is disclosed. The process entails reacting in the presence of at least one phosphonium salt as catalyst, at least one diphenol, at least one carbonic acid diester, and at least one alkyl group-substituted phenol chain terminator. The chain terminator is introduced in free form or as a transesterifiable compound under the conditions of the synthesis. The polycarbonate thus produced is suitable for preparing a variety of molded articles.

    专利号:US-6716933-B2
    优先权日:2001-07-19
    标题:Working up of polymer synthesis solutions
    发明人:ALEWELT WOLFGANG; EBERT WOLFGANG; FRITZ THOMAS; JAHN DIRK; WESTERNACHER STEFAN; BRUYNSEELS FRANK; RECHNER JOHANN
    权利人:BAYER AG
    摘要:The present invention relates to a process for working up solutions of polymers in organic solvents contaminated by alkaline constituents, using homogeneously soluble acids, especially by the introduction of an acid gas, and subsequent washing, and to the polymers so obtainable, which are distinguished by the fact that, on treatment with moist heat (sterilisation), only few defects caused by decomposition are formed, to the use thereof in the production of extrudates and molded specimen, and to the extrudates and molded specimen produced from those polymers themselves.

    专利号:US-4269964-A
    优先权日:1978-09-27
    标 题:Polycarbonates with alkylphenyl end groups, their preparation and their use
    发明人:FREITAG DIETER; NOUVERTNE WERNER; BURKHARDT CLAUS; KLEINER FRANK
    权利人:BAYER AG
    摘要:This development is concerned with aromatic thermoplastic polycarbonates with special chain terminators which give the polymers enhanced hydrolysis resistance and impact toughness. These chain terminators are alkyl substituted monohydroxy phenyls in which each phenyl is substituted by one alkyl group having 8 or 9 carbon atoms and about 47 to 89% of its hydrogen atoms trisubstituted on carbon atoms with up to about 20% of the substituents in the ortho position and the balance at the para position. This development is also concerned with a process for synthesizing such polymers by using such chain terminators as reactants in generically known synthesis methods for polycarbonates.

    专利号:KR-20030009191-A
    优先权日:2001-07-19
    标 题 :Working Up of Polymer Synthesis Solutions

    专利号:DE-10135314-A1
    优先权日:2001-07-19
    标 题:Refurbishment of polymer synthesis solutions
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    合成参考文献


    摘要:Acute Toxicity Data. Journal of the American College of Toxicology, Part B., 15(Suppl
    摘要:S109 | PARCEDC | List of 7074 potential endocrine disrupting compounds (EDCs) by PARC T4.2 | DOI:10.5281/zenodo.10944198
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