CAS: 57625-74-8; Methyl 2-Methyl-2-Phenylpropanoate

上下游产品

Alpha-甲基苯乙酸甲酯 2-Phenylpropionic Acid Methyl Ester 31508-44-8
Alpha,Alpha-二甲基苯乙酸 2-Methyl-2-Phenylpropionic Acid 826-55-1
Methyl 2-(2-Bromophenyl)-2-Methylpropanoate 177748-63-9
苯乙酸甲酯 Benzeneacetic Acid Methyl Ester 101-41-7
2-甲基-2-苯基丙烷-1-醇 2-Methyl-2-Phenyl-Propan-1-Ol 2173-69-5

2-甲基-2-苯基丙腈置于甲烷磺酸,Potassium Hydroxide体系中,用 乙醇,水 作为反应溶剂,化学反应 2.0H,反应生成 2,2-二甲基苯乙酸甲酯
参考文献: Olefin Substituted Oxindoles Having Ampk Activity[fr] Oxindoles Substitués Par Oléfine Ayant Une Activité Sur Ampk
标题: Olefin Substituted Oxindoles Having Ampk Activity[fr] Oxindoles Substitués Par Oléfine Ayant Une Activité Sur Ampk
摘要:本发明涉及具有有价值的药理特性的式(I)化合物,特别是ampk激活剂,因此在治疗某些可以通过激活该受体预防或治疗的疾病方面具有用处.这些化合物适用于治疗和预防可以受该受体影响的疾病,如代谢性疾病,特别是2型糖尿病.

专利信息

专利号:US-5663480-A
优先权日:1993-12-20
标题:Synthesis of aromatic carbonates by transesterification using a catalyst comprising a microporous material and a group IV metal
发明人：TSUNEKI HIDEAKI; KIRISHIKI MASARU; WATANABE KENICHI; ONDA YOSHIYUKI
权利人:NIPPON CATALYTIC CHEM IND
摘要:A catalyst for producing an aryl ester of a carbonic or carboxylic acid is disclosed, which includes a microporous material containing a metal element belonging to group IV. This catalyst can be used as a heterogeneous catalyst to produce the aryl ester in high yield with industrial advantages. In order to produce the aryl ester using the catalyst, a carbonate or an aliphatic carboxylate is transesterified with an aromatic hydroxy compound, or an aryl carboxylate is transesterified with a carbonate, or an alkyl aryl carbonate is disproportionated by transesterification.

专利号:CN-103857660-A
优先权日:2011-06-30
标 题:For PET imaging18Direct synthesis of F-fluoromethoxy compounds and use thereof in direct radiosynthesis of O- ([ 2 ]18F]Novel precursors of protected derivatives of fluoromethyl) tyrosine

专利号:CN-113072504-B
优先权日:2021-03-29
标题 :A kind of chemical synthesis method of bosentan metabolite

专利号:US-6974829-B2
优先权日:2002-05-07
标 题:Succinoyl aminopyrazoles and related compounds
发明人：TUNG JAY S; GUINN ASHLEY C; THORSETT EUGENE D; PLEISS MICHAEL A
权利人:ELAN PHARM INC
摘要:This invention is directed to a class of compounds (Formula I) including succinoyl amino pyrazoles, succinoyl amino thiadiazoles, succinoyl amino acid esters, succinoyl amino acid amides, succinoyl amino alcohols, succinoyl amino ketones, succinoyl amino hydantoins, succinoyl anilines, and succinoyl derivatives of privileged structures. The invention is also directed to a pharmaceutical formation comprising such compound in a pharmaceutically acceptable salt form or prodrug thereof. The invention is further directed to a method for inhibiting β-amyloid peptide release and/or synthesis, a method for inhibiting γ-secretase activity and a method for treating neurological disorders associated with β-amyloid peptide production. The method comprises administering to a host a pharmaceutical formulation comprising an effective amount of a compound of Formula I. The compounds of Formula I are useful in the prevention and treatment of Alzheimer's disease.

专利号:US-7053220-B2
优先权日:2002-02-01
标 题 :Hydroxyalkanoyl aminopyrazoles and related compounds
发明人：TUNG JAY S; GUINN ASHLEY C; THORSETT EUGENE D; PLEISS MICHAEL A
权利人:ELAN PHARM INC
摘要:This invention is directed to a class of compounds (Formula I) including hydroxyalkanoyl amino pyrazoles, hydroxyalkanoyl amino thiadiazoles, hydroxyalkanoyl amino acid esters, hydroxyalkanoyl amino acid amides, hydroxyalkanoyl amino alcohols, hydroxyalkanoyl amino ketoes, hydroxyalkanoyl amino hydantoins, hydroxyalkanoyl anilines, and hydroxyalkanoyl derivatives of privileged structures. The invention is also directed to a pharmaceutical formation comprising such compound in a pharmaceutically acceptable salt form or prodrug thereof. The invention is further directed to a method for inhibiting β-amyloid peptide release and/or synthesis, a method for inhibiting γ-secretase activity and a method for treating neurological disorders associated with β-amyloid peptide production. The method comprises administering to a host a pharmaceutical formulation comprising an effective amount of a compound of Formula I. The compounds of Formula I are useful in the prevention and treatment of Alzheimer's disease.

专利号:CN-113072504-A
优先权日:2021-03-29
标题 :A chemical synthesis method of bosentan metabolites