CAS: 138060-07-8; Piperidin-3-Amine Dihydrochloride

相似化合物

54012-73-6 334618-07-4 334618-23-4

Racemic Nipecotic Acid Hydrazide Dihydrochloride,异丙醇,亚硝酸异戊酯,盐酸置于甲醇,丙酮体系中,用 水 用作溶剂,化学反应 13.17H,以3.42 G Of Racemic 3-Aminopiperidine Dihydrochloride (20 Mmol,Corresponds To 80% Yield) With A Water Content Of 0.64% Were Obtained的收率获得3-氨基哌啶二盐酸盐
参考文献:Process For The Preparation Of Enantiomerically Enriched 3-Aminopiperidine
标题:Process For The Preparation Of Enantiomerically Enriched 3-Aminopiperidine
摘要:本发明涉及一种制备对映富集的3-氨基哌啶,特别是其r-对映体(R)-3-氨基哌啶的方法.本发明还涉及一种对映富集的中间体及用于获得apip单一对映体的特定酸加成盐,以及结晶的(R)-3-氨基哌啶-双氯化物-一水合物和结晶的(S)-3-氨基哌啶-双氯化物-一水合物.

专利信息

专利号:US-11401269-B2
优先权日:2018-05-15
标 题 :Intermediates and processes for the preparation of Linagliptin and its salts
发明人：CIANCIMINO CRISTINA; TRAGNI MICHELE; VIGO DANIELE; PICCOLO ORESTE
权利人:CAMBREX PROFARMACO MILANO S R L
摘要:Disclosed are new intermediates for the synthesis of Linagliptin and of its salts and a process for its preparation involving said intermediates.

专利号:CN-110724675-A
优先权日:2019-10-31
标题:Transaminase catalyst and method for enzymatic synthesis of (R)-1-tert-butoxycarbonyl-3-aminopiperidine

专利号:CN-104387315-A
优先权日:2013-11-12
标 题:Compound I and (R)-3-aminopiperidine hydrochloride II, its preparation method and its application in the synthesis of linagliptin

专利号:CN-104387315-B
优先权日:2013-11-12
标 题 :Compound I and (R)-3-aminopiperidine hydrochloride II, its preparation method and its application in the synthesis of linagliptin

专利号:CN-110724675-B
优先权日:2019-10-31
标题 :Transaminase catalyst and method for enzymatic synthesis of (R)-1-tert-butoxycarbonyl-3-aminopiperidine

专利号:CN-113121414-B
优先权日:2020-01-15
标题 :A kind of synthesis method of trolagliptin intermediate