CAS: 16473-35-1; (4-(Chloromethyl)Phenyl)Methanol

相似化合物

1642-81-5 34040-64-7 73291-09-5

上下游产品

CAS号1642-81-5 4-氯甲基苯甲酸 | CAS号589-29-7 对苯二甲醇 | CAS号34040-64-7 4-氯甲基苯甲酸甲酯 | CAS号262862-97-5 [4-(苯氧基甲基)苯基]甲醇 | CAS号73291-09-5 对氯甲基苯甲醛 | CAS号171358-70-6 4-(四氢吡喃基氧基甲基)苄氯 | CAS号151867-81-1 (4R,5S,6S,7R)-4... | CAS号731846-75-6 (E)-甲基3-(4-(氯甲基...

对苯二甲醇置于氯化亚砜体系中,用 氯仿 用作溶剂,化学反应 1.0H,以75%的收率获得4-(氯甲基)苯甲基醇
参考文献:Hiv-1蛋白酶抑制剂dmp 323的立体选择性合成.
标题:Hiv-1蛋白酶抑制剂dmp 323的立体选择性合成.
摘要:Dmp 323是一种有效的hiv-1蛋白酶抑制剂,已经通过有效的立体选择性方法合成,适用于大规模制备.核心的c(2)对称二醇是由cbz保护的d-苯丙氨酸的立体选择性频哪醇偶联合成的.明智地选择保护基团可以在温和条件下形成环状脲,增强了双烷基化的难度,并导致了无需色谱即可轻松纯化的中间体.另外,开发了一种单锅高产率方法,以从1,4-苯二甲醇制备烷基化剂4-[((三苯基甲氧基)甲基]苄基氯.
Doi:10.1021/jo951847U

专利信息

专利号:US-4536599-A
优先权日:1978-08-22
标题:Synthesis of amine derivatives
发明人：MASUKO FUJIO; KATSURA TADASHI
权利人:SUMITOMO CHEMICAL CO
摘要:An amine of the formula, ##STR1## wherein R 1 , R 2 , R 3 , R 4 and R 5 are each hydrogen, alkyl or the like and n is 1, 2 or 3, including α-phenyl-β-(p-tolyl)-ethylamine, which is useful as an optically resolving agent, an intermediate of medicines and the like, is effectively produced by a novel process comprising hydrolysis of the corresponding nitrile of the formula, ##STR2## wherein R 1 , R 2 , R 3 , R 4 , R 5 and n are the same as above, followed by alkali-decomposition of the resulting amide of the formula, ##STR3## wherein R 1 , R 2 , R 3 , R 4 , R 5 and n are the same as above. An amide including the above one is effectively produced by hydrolysis of the corresponding nitrile in the presence of a base and hydrogen peroxide using an organic quaternary ammonium salt and/or a tertiary amine as a catalyst.

专利号:US-9193682-B2
优先权日:2013-04-05
标题:Synthesis of trithiocarbonates and allyl sulfides and their application into advances in covalent adaptable networks
发明人：FENOLI CHRISTOPHER R; BOWMAN CHRISTOPHER N
权利人:FENOLI CHRISTOPHER R; BOWMAN CHRISTOPHER N
摘要:Monomers having a C-B-A-B-C structure are disclosed, where A is a core of either trithiocarbonate and allyl sulfide, where B are linker units, and where C are end units. The end units may comprise acrylates, methacrylates, alcohol(s), amine(s), and alkynes, among others. The linker units may include an alkane, alkene, phenyl, diphenyl, or benzylic group, among others. Methods of synthesizing such compounds are also disclosed.

专利号:US-6160152-A
优先权日:1998-02-10
标 题:Process for the synthesis of oligomeric compounds
发明人：CAPALDI DANIEL C; RAVIKUMAR VASULINGA T
权利人:ISIS PHARMACEUTICALS INC
摘要:Synthetic processes are provided wherein oligomeric compounds are prepared having phosphodiester, phosphorothioate, and phosphorodithioate covalent linkages. Also provided are synthetic intermediates useful in such processes.

专利号:US-6020475-A
优先权日:1998-02-10
标 题:Process for the synthesis of oligomeric compounds

专利号:US-2014303391-A1
优先权日:2013-04-05
标题:Synthesis of trithiocarbonates and allyl sulfides and their application into advances in covalent adaptable networks

专利号:RU-2096404-C1
优先权日:1990-07-31
标 题:Substituted sulfoneamides, substituted cyclic amines as intermediate compounds for the synthesis of the substituted sulfoneamides and pharmaceutical composition showing antagonistic activity with respect to thromboxane a2 receptors