CAS: 28768-32-3; 4,4-Methylenebis(N,N-Bis(Oxiran-2-Ylmethyl)Aniline)

4,4'-二氨基二苯甲烷置于四丁基硫酸氢铵,溶剂黄146,Sodium Hydroxide体系中,用 水 用作溶剂,化学反应 2.0H,反应生成N,N,N,N,-四环氧丙基-4,4-二氨基二苯甲烷
参考文献:Manufacturing Method For Compound Having N,N-Bis(2-Hyroxy-3-Chloropropyl)Amino Group
标题:Manufacturing Method For Compound Having N,N-Bis(2-Hyroxy-3-Chloropropyl)Amino Group
摘要:一种高效且安全地在工业规模上制造具有n,N-双(2-羟基-3-氯丙基)氨基基团的化合物的方法.将胺化合物或其溶液,环氧氯丙烷或其溶液,以及酸性化合物或其溶液连续供给到流动反应器中,在40至130oc的反应温度和0.2至10 H−1的液体空间速度下反应,从而制造出具有n,N-双(2-羟基-3-氯丙基)氨基基团的化合物.通过与碱反应将获得的具有n,N-双(2-羟基-3-氯丙基)氨基基团的化合物脱氯化,从而制造出一种多功能环氧化胺型环氧化合物.

专利信息

专利号:US-11884772-B2
优先权日:2020-08-21
标题:Phenylphosphine oxide and oxygen stable epoxy polymers and methods of synthesis
发明人：FUCHS WITOLD K; WIGGINS JEFFREY
权利人:THE UNIV OF SOUTHERN MISSISSIPPI
摘要:A polymer formed of at least one phenylphosphine oxide functional epoxide crosslinked with at least one phenylphosphine oxide amine such that the polymer has phosphorous concentrations of at least about 8 percent by weight, at least about 8.5 percent by weight, or any value or range of values therebetween.

专利号:US-11738328-B2
优先权日:2021-04-30
标题:Single-step synthesis of chemisorption fiber sorbents (CHEFS) for the capture of CO2 and removal of water contaminants
发明人：GRAY MCMAHAN L; SHI FAN; YI SHOULIANG; WILFONG WALTER CHRIS; WANG QIUMING
权利人:US ENERGY
摘要:One or more embodiments relates to method for generating CHEFS having the steps of generating the CHEFS from a dope. One or more embodiments relates to a method for generating CHEFS having amine functional groups having the steps of generating a dope containing a BIAS with amine groups, at least one polymer, and at least one solvent; and forming CHEFS from the dope, wherein the generated CHEFS have no more than 30% amine loss compared to the BIAS.

专利号:EP-4574877-A1
优先权日:2023-12-19
标题:Synthesis of activated vitrimer anhydride epoxy resin
发明人：MORETTO ENZO; PILUSO PIERRE
权利人:COMMISSARIAT ENERGIE ATOMIQUE
摘要:A method of manufacturing an activated vitrimer epoxy anhydride resin, intended for the reshaping of composite material parts comprising an epoxy anhydride resin and glass fibers, the manufacturing method comprising the following steps: - a) preparation of a solution from a mixture of three precursor components comprising a polyanhydride, an aminoalcohol, a polyepoxy and a solvent, - b) stirring the solution, - c) evaporation of the solvent so as to obtain a precursor mixture of the activated epoxy-vitrimer anhydride resin, and - d) crosslinking by applying a heat treatment so as to obtain the activated vitrimer epoxy anhydride resin.

专利号:US-2008051323-A1
优先权日:2004-08-21
标 题 :Chloroquine drug compositions and methods for their synthesis
发明人：KOSAK KENNETH M
权利人:KOSAK KENNETH M
摘要:This invention discloses compositions of chloroquine-coupled active agents, including methods for their preparation. The prior art has shown that chloroquines given as free drug in high enough concentration, enhances the release of various agents from cellular endosomes into the cytoplasm. The purpose of these compositions is to provide a controlled amount of chloroquine at the same site where the active agent is delivered, thereby reducing the overall dosage needed. n The compositions comprise a chloroquine substance coupled to an active agent directly or through a variety of pharmaceutical carrier substances. The carrier substances include polysaccharides, synthetic polymers, proteins, micelles and other substances for carrying and releasing the chloroquine compositions in the body for therapeutic effect. The compositions can also include a biocleavable linkage for carrying and releasing active agents for therapeutic or other medical uses. The invention also discloses carrier compositions that are coupled to targeting molecules for targeting the delivery of chloroquine substances and active agents to their site of action.

专利号:US-2023182087-A1
优先权日:2020-04-28
标 题:Thin-Film Composite Membranes Synthesized by Multi-Step Coating Methods
发明人：DAVENPORT DOUGLAS; VANKELECOM IVO; VERBEKE RHEA
权利人:UNIV LEUVEN KATH
摘要:The invention relates to methods for the synthesis of a thin-film composite membrane, comprising the following steps: a) providing an ultrafiltration porous support membrane, coated at the outer surface with a thin film, synthesized through interfacial polymerisation or interfacial initiation of polymerisation, b) contacting the membrane with a first solution comprising a first monomer, and allowing the solution to impregnate inside the thin film of the membrane, c) discarding the first solution comprising the first monomer, d) contacting the membrane with a second solution comprising a second monomer, and allowing the solution to impregnate inside the thin film of membrane, whereby the second monomer reacts with the first monomer and optionally with reactive groups of the thin film, e) discarding the second solution comprising the second monomer.

专利号:US-2007060499-A1
优先权日:2005-09-15
标 题 :Chloroquine combination drugs and methods for their synthesis
发明人：KOSAK KENNETH M
权利人:KOSAK KENNETH M
摘要:This invention discloses compositions of chloroquine-coupled active agents, including methods for their preparation. The prior art has shown that chloroquines given as free drug in high enough concentration, enhances the release of various agents from cellular endosomes into the cytoplasm. The purpose of these compositions is to provide a controlled amount of chloroquine at the same site where the active agent is delivered, thereby reducing the overall dosage needed. The compositions comprise a chloroquine substance coupled to an active agent directly or through a variety of pharmaceutical carrier substances. The carrier substances include polysaccharides, synthetic polymers, proteins, micelles and other substances for carrying and releasing the chloroquine compositions in the body for therapeutic effect. The compositions can also include a biocleavable linkage for carrying and releasing active agents for therapeutic or other medical uses. The invention also discloses carrier compositions that are coupled to targeting molecules for targeting the delivery of chloroquine substances and active agents to their site of action.