相似化合物
55330-60-4 1073-62-7 20570-96-1物理性质
- 熔点143°C
- 沸点87.5 °C at 760mmHg
- 闪点21.1 °C
- 密度0.8g/cm3
- PSA:112.65
- LogP:-1.5733
- 蒸汽压1.07E-07 mmHg at 25 °C
- 溶解性DMSO, Water
- 外观形态白色至类白色固体
- 储存条件请置于阴暗处, 惰性气氛中,室温
- 产品应用甲基苄肼(异丙胺酰苄肼)的中间体.甲基肼为火箭燃料.
- 性质描述该品为甲基肼的硫酸盐.甲基肼为澄明液体,沸点87.5°C,呈强还原性,与强氧化剂接触易燃烧,闪点70°C,对皮肤及黏膜有强刺激性,并显示很强的生理毒性;甲基肼硫酸盐为白色片状结晶,熔点141-142°C,使用比较安全.
欧盟法规
ECHA物质C&L通报REACH预注册上下游产品
CAS号60-34-4 甲基肼 | CAS号77-78-1 硫酸二甲酯 | CAS号28867-76-7 苄连氮 | CAS号71-43-2 苯 | CAS号56079-16-4 1,3,5-三甲基-1-H-吡... | CAS号3524-32-1 1,3-二甲基-1氢-吡唑-5-胺 | CAS号33548-32-2 1-甲基-6-氧代-1,4,5... | CAS号92406-53-6 5-氨基-1-甲基吡唑-3-甲酸甲酯 | CAS号22718-48-5 Hydrazinecarbox... | CAS号4114-33-4 1-(carbamoylami... | CAS号933-76-6 4,5-二氯-2-甲基哒嗪-3-酮 | CAS号2749-59-9 1,3-二甲基-5-吡唑酮 | CAS号21075-83-2 1-叔丁氧羰基-1-甲基肼 | CAS号5334-41-8 1-甲基-4-氰基-5-氨基-...甲基肼置于硫酸体系中,化学反应 4.0H,反应生成甲基肼硫酸盐
参考文献:Novel Pyrazole-3-Carboxamide Derivative Having 5-Ht2B Receptor Antagonist Activity
标题:Novel Pyrazole-3-Carboxamide Derivative Having 5-Ht2B Receptor Antagonist Activity
摘要:揭示的是由通式(i)表示的化合物或其药用可接受盐,其作为5-Ht2B受体的选择性拮抗剂是有用的.该化合物和盐可用于治疗或预防与5-Ht2B受体相关的各种疾病和症状.
专利信息
专利号:US-6867202-B1
优先权日:1997-06-25
标 题 :Treatment of insulin resistance
发明人:CARPINO PHILIP ALBERT; CHIU CHARLES KWOK-FUNG; PAN LYDIA CODETTA; LEFKER BRUCE ALLEN; TREADWAY JUDITH LEE; ZAWISTOSKI MICHAEL PAUL
权利人:PFIZER
摘要:This invention is directed to methods of treating insulin resistance in a mammal which comprise administering an effective amount of a compound of formula I, n n nwhere the variables are defined in the specification, or the stereoisomeric mixtures, diastereomerically enriched, diastereomerically pure, enantiomerically enriched or enantiomerically pure isomers, or the pharmaceutically acceptable salts and prodrugs thereof to said mammal. The compounds of formula I are growth hormone secretagogues and as such are useful for increasing the level of endogenous growth hormone. In another aspect this invention provides certain intermediates which are useful in the synthesis of the foregoing compounds and certain processes useful for the synthesis of said intermediates and th compounds of formula I. This invention is further directed to methods comprising administering to a human or other animal a combination of a functional somatostatin antagonist such as an alpha-2 adrenergic agonist and a compound of formula I.
专利号:CN-101402586-A
优先权日:2008-11-07
标 题:Synthesis of 1-methylhydrazine
专利号:CN-105037196-B
优先权日:2015-08-10
标题 :A new method of catalytic synthesis of methylhydrazine under normal pressure
专利号:CN-105037196-A
优先权日:2015-08-10
标题 :A new method of catalytic synthesis of methylhydrazine under normal pressure
专利号:IL-138911-A
优先权日:1995-12-28
标 题:Dipeptide intermediate compound in the synthesis of growth-hormone secretagogues
专利号:CN-109721538-A
优先权日:2017-10-28
标题 :A kind of new synthesis method of 1-methyl-3-propyl pyrazole-5-carboxylic acid