对氟甲苯置于n-溴代丁二酰亚胺(Nbs)体系中,化学反应生成 4-氟苯基丙酮 参考文献:Adcock,W. Et Al.,Australian Journal Of Chemistry,1970,Vol. 23,P. 1921-1937 标题:Adcock,W. Et Al.,Australian Journal Of Chemistry,1970,Vol. 23,P. 1921-1937
专利号:US-11401240-B2 优先权日:2018-11-08 标 题:Process for the synthesis of lactams 发明人:DAWKINS DAVID ANTHONY; KOTSAKIS PANAGIOTIS; PARRY NEIL JAMES; THORNTHWAITE DAVID WILLIAM 权利人:CONOPCO INC 摘要:A process for the synthesis of lactams suitable for use in antimicrobial, anti-biofilm and bacteriostatic compositions.
专利号:US-10377707-B2 优先权日:2015-08-20 标 题:Process for the preparation of lactams from glyoxalic acid 发明人:NORBURY ANDREW MARTYN; THORNTHWAITE DAVID WILLIAM 权利人:CONOPCO INC 摘要:A process for the synthesis of lactams suitable for use in antimicrobial, anti-biofilm bacteriostatic compositions.
专利号:WO-2004058727-A1 优先权日:2002-12-20 标题 :Substituted 3,5-dihydro-4h-imidazol-4-ones for the treatment of obesity 发明人:CHEN YUANWEI; O'CONNOR STEPHEN JAMES; GUNN DAVID; NEWCOM JASON; CHEN JIANQING; YI LIN; ZHANG HAI-JUN; HUNYADI LASZLO MATYAS; NATERO REINA 权利人:BAYER PHARMACEUTICALS CORP; CHEN YUANWEI; O'CONNOR STEPHEN JAMES; GUNN DAVID; NEWCOM JASON; CHEN JIANQING; YI LIN; ZHANG HAI-JUN; HUNYADI LASZLO MATYAS; NATERO REINA 摘要:This invention relates to substituted 3,5-dihydro-4H-imidazol-4-ones compounds which are useful in the treatment of obesity and obesity-related disorders, and as weight-loss and weight-control agents. The invention also provides methods for synthesis of the compounds, pharmaceutical compositions comprising the compounds, and methods of using such compositions for inducing weight loss and treating obesity and obesity-related disorders.
专利号:US-2014303333-A1 优先权日:2011-10-14 标题:Iron bisphenolate complexes and methods of use and synthesis thereof 发明人:SHAVER MICHAEL P; KOZAK CHRISTOPHER M 权利人:UNIV PRINCE EDWARD ISLAND; GENESIS GROUP INC 摘要:The present application, relates to iron bisphenolate complexes and methods of use and synthesis thereof. The iron complexes are prepared from tridentate or tetradentate ligands of Formula I: wherein R 1 and R 2 are as defined herein. Also provided are methods and processes of using the iron bisphenolate complexes as catalysts in cross-coupling reactions and in controlled radical polymerizations.
专利号:EP-3170807-A1 优先权日:2015-11-23 标题:New method for synthesis of fenfluramine, of isomers therof and/or of analogs thereof, and new compositions comprising it
专利号:WO-2007104696-A1 优先权日:2006-03-15 标题 :Antimalarial agents having polyaromatic structure 发明人:CAMPIANI GIUSEPPE; GEMMA SANDRA; FATTORUSSO CATERINA; KUKREJA GAGAN; JOSHI BHUPENDRA PRASAD; TAGLIALATELA SCAFATI ORAZIO; SAVINI LUISA; DE ANGELIS MERI; FATTORUSSO ERNESTO 权利人:SIGMA TAU IND FARMACEUTI; CAMPIANI GIUSEPPE; GEMMA SANDRA; FATTORUSSO CATERINA; KUKREJA GAGAN; JOSHI BHUPENDRA PRASAD; TAGLIALATELA SCAFATI ORAZIO; SAVINI LUISA; DE ANGELIS MERI; FATTORUSSO ERNESTO 摘要:Antimalarial agents having a novel pharmacophore of formula (I) are herein described. These polycyclic compounds are able to inhibit chloroquine-sensitive and chloroquine-resistant strains of Plasmodium falciparum (Pf). Furthermore, the synthesis of these compounds involves few steps from commercial products with low cost of production.
参考标题:Thioether-Linked Dihydropyrrol-2-One Analogues As Pqsr Antagonists Against Antibiotic Resistant Pseudomonas Aeruginosa 作者:Shekh Sabir,Dittu Suresh,Sujatha Subramoni,Theerthankar Das,Mohan Bhadbhade,David Stc. Black,Scott A. Rice,Naresh Kumar |发布日期:2021.2 摘要:Pseudomonas Quinolone System (Pqs) Is One Of The Key Quorum Sensing Systems In Antibiotic-Resistant P. Aeruginosa And Is Responsible For The Production Of Virulence Factors And Biofilm Formation. Thus, Synthetic Small Molecules That Can Target The Pqsr (Mvfr) Receptor Can Be Utilized As Quorum Sensing Inhibitors To Treat P. Aeruginosa Infections. In This Study, We Report The Synthesis Of Novel Thioether-Linked
合成参考文献
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