三甲基硅基甲醇,三氟甲磺酸酐 以 二氯甲烷 作为反应溶剂,以64%的收率获得产物(三甲基硅基)甲基三氟甲烷磺酸酯 参考文献: Rapamycin Analogs As Anti-Cancer Agents[fr] Analogues De Rapamycine En Tant Qu'Agents Anti-Cancéreux 标题: Rapamycin Analogs As Anti-Cancer Agents[fr] Analogues De Rapamycine En Tant Qu'Agents Anti-Cancéreux 摘要:提供了雷帕霉素的类似物和衍生物,其中这些类似物和衍生物可以结合fk-506结合蛋白(fkbp),或抑制fkbp的mtor功能,或两者兼而有之.这些雷帕霉素的类似物和衍生物包括在42-羟基团上用特定的化学可行基团取代的雷帕霉素骨架.提供了在治疗癌症等疾病中使用雷帕霉素类似物和衍生物的方法,以及合成这些雷帕霉素类似物和衍生物的方法.
专利号:US-4139403-A 优先权日:1977-08-19 标题:Dinitroalkyl and fluorodinitroalkyl silicon compounds 发明人:BAUM KURT; LERDAL DUANE A; HORN JERALD S 权利人:US NAVY 摘要:Energetic silicon compounds of the general formulae ##STR1## The gem dinitro compounds are prepared from alkyl bromide silanes by sod nitrite displacement and oxidative nitration. The compounds are then fluorinated. To prepare the polysiloxanes, phenyl blocking groups are used during synthesis of the fluoro dinitro moiety and are then replaced with bromine and the monomer is hydrolyzed.
专利号:US-11279723-B2 优先权日:2018-07-03 标 题 :Metallocene synthesis process 发明人:HARLAN CHARLES J; HOLTCAMP MATTHEW W; KUPPUSWAMY SUBRAMANIAM; HAAS STEVEN C 权利人:EXXONMOBIL CHEMICAL PATENTS INC 摘要:A process to synthesize a Group 4 ansa-metallocene. The process includes reacting an alkaline earth metal dianion dicyclopentadiene ligand-Lewis base complex with a Group 4 metal tetrahalide in the presence of an alkali metal halide, and forming the Group 4 ansa-metallocene dihalide with high yield and purity.
专利号:US-2006211792-A1 优先权日:2003-08-01 标 题:Triangulenium fluorescent dyes and polymers comprising such dyes 发明人:LAURSEN BO W 权利人:LAURSEN BO W 摘要:The invention relates to fluorescent dyes comprising a triangulene structure in the form of a ring system of six, six-membered rings fused in a triangular fashion. The dyes are useful for visualisation of chemical compounds including polymer matrices for e.g. chromatographic separation and isolation of desirable chemical moieties, and for chemical library synthesis.