CAS: 936-12-9; Ethyl 2-Methyl-1H-Pyrrole-3-Carboxylate

相似化合物

37102-48-0 2199-51-1 3168-85-2

上下游产品

2-甲基-1H-吡咯-3-羧酸 2-Methyl-1H-Pyrrole-3-Carboxylic Acid 37102-48-0
1-Carbamoyl-2-Methyl-Pyrrole-3-Carboxylic Acid Ethyl Ester 54449-03-5
1-Acetyl-2-Methyl-1H-Pyrrol-3-Carbonsaeure-Ethylester 74469-98-0

3-氨基巴豆酸乙酯置于二异丁基氢化铝体系中,用 四氢呋喃,甲醇 作为反应溶剂,化学反应 13.0H,反应生成 2-甲基吡咯-3-甲酸乙酯
参考文献:Weinreb酰胺在克诺尔吡咯合成中的多功能性
标题:Weinreb酰胺在克诺尔吡咯合成中的多功能性
摘要:从烯胺和weinrebα-氨基酰胺开始制备n-甲氧基-N-甲基-α-烯氨基羧酰胺.它们与含金属金属化合物的反应和随后的环化反应是克诺尔吡咯合成中的一种通用选择.
DOI:10.1016/s0040-4020(99)00289-6

专利信息

专利号:US-2007099915-A1
优先权日:2005-10-07
标题 :Inhibitors of the hiv integrase enzyme
发明人：DRESS KLAUS R; JOHNSON TED W; PLEWE MICHAEL B; TANIS STEVEN P; ZHU HUICHUN
权利人:PFIZER
摘要:The present invention is directed to compounds of formula (I), n nand pharmaceutically acceptable salts and solvates thereof, their synthesis, and their use as modulators or inhibitors of the human immunodeficiency virus (“HIVâ€?) integrase enzyme.

专利号:US-7468375-B2
优先权日:2004-04-26
标题:Inhibitors of the HIV integrase enzyme
发明人：DRESS KLAUS RUPRECHT; HU QIYUE; JOHNSON TED WILLIAM; PLEWE MICHAEL BRUNO; TANIS STEVEN PAUL; WANG HAI; YANG ANLE; YIN CHUNFENG; ZHANG JUNHU
权利人:PFIZER
摘要:The present invention is directed to compounds of formula (I), and pharmaceutically acceptable salts and solvates thereof, their synthesis, and their use as modulators or inhibitors of the human immunodeficiency virus (“HIVâ€?) integrase enzyme.

专利号:US-2009170846-A1
优先权日:2005-10-03
标题 :Inhibitors of the hiv integrase enzyme
发明人：DRESS KLAUS RUPRECHT; PLEWE MICHAEL BRUNO; JOHNSON TED WILLIAM; TANIS STEVEN PAUL; TRAN KHANH TUAN
权利人:PFIZER
摘要:The present invention is directed to compounds of formula (I), and pharmaceutically acceptable salts and solvates thereof, their synthesis, and their use as modulators or inhibitors of the human immunodeficiency virus “HIVâ€? integrase enzyme. Formula (I).

专利号:EP-1873155-A1
优先权日:2004-04-26
标题:Inhibitors of the HIV integrase enzyme
发明人：DRESS KLAUS RUPRECHT; HU QIYUE; JOHNSON TED WILLIAM; PLEWE MICHAEL BRUNO; TANIS STEVEN PAUL; ZHU HUICHUN; ZHANG JUNHU
权利人:PFIZER
摘要:The present invention is directed to compounds of formula (I),n nand pharmaceutically acceptable salts and solvates thereof, their synthesis, and their use as modulators or inhibitors of the human immunodeficiency virus ('HIV') integrase enzyme.

专利号:US-7692014-B2
优先权日:2004-04-26
标题:Inhibitors of the HIV integrase enzyme
发明人：DRESS KLAUS RUPRECHT; HU QIYUE; JOHNSON TED WILLIAM; PLEWE MICHAEL BRUNO; TANIS STEVEN PAUL; ZHU HUICHUN; ZHANG JUNHU
权利人:PFIZER
摘要:The present invention is directed to compounds of formula (I), n nand pharmaceutically acceptable salts and solvates thereof, their synthesis, and their use as modulators or inhibitors of the human immunodeficiency virus (“HIVâ€?) integrase enzyme.