CAS: 1806-26-4; 4-Octylphenol

该化合物是一种含有分子式C14H22O的烷基酚化合物.其特征特征是附于苯酚环的副位置的八溴二苯醚组,具有中度疏水性.该化合物由于具有提高非极化系统溶性性和稳定性的能力,通常用作表面活性剂,树脂和塑化剂合成的中间体.其化学结构也使其适合用于聚合工艺和特殊化学品前体.4-有机酚具有一贯的纯度和再活性,确保工业配方的可靠性能.由于它对环境和健康的潜在影响,建议进行适当的处理.

结构式图片

欧盟法规

欧盟《植物保护产品法规》ECHA物质ECHA物质C&L通报欧盟《水框架指令》附件XREACH预注册

上下游产品

CAS号2589-73-3 4’-羟基苯辛酮 | CAS号111-64-8 辛酰氯 | CAS号108-95-2 苯酚 | CAS号111-66-0 1-辛烯 | CAS号124-07-2 辛酸 | CAS号5457-78-3 phenyl °Ctanoate | CAS号16245-79-7 4-辛基苯胺 | CAS号62170-25-6 1-(4-methoxyphe... | CAS号3307-19-5 4-°Ctylanisole | CAS号18733-06-7 2-amino-4-°Ctyl... | CAS号28488-49-5 2-hydroxy-5-°Ct... | CAS号24777-05-7 2-nitro-4-°Ctyl... | CAS号13222-43-0 2-[(2-hydroxy-5... | CAS号3307-19-5 4-°Ctylanisole | CAS号15234-85-2 4-辛基苯氧基乙酸 | CAS号112921-43-4 2,6-bis(bromome... | CAS号83797-33-5 3-°Ctylhexanedi... | CAS号89202-50-6 benzoic acid,4-... | CAS号4527-48-4 4-°Ctylbenzenethiol

合成工艺路线路线简述

  • 合成目标产物 4-N-Octylphenol 主要起始原料 Phenol
  • (文献来源)合成步骤主要原料 Phenol
1-甲氧基-4-辛基苯置于氢碘酸,溶剂黄146体系中,化学反应生成4-辛基酚
参考文献:Sonawane,H.R. Et Al.,Indian Journal Of Chemistry,1965,Vol. 3,P. 260-265
标题:Sonawane,H.R. Et Al.,Indian Journal Of Chemistry,1965,Vol. 3,P. 260-265

海关参考信息

专利信息


专利号:US-10768157-B2
优先权日:2015-10-20
标 题:Materials and methods for the detection of trace amounts of substances in biological and environmental samples
发明人:KABIR ABUZAR; FURTON KENNETH G
权利人:KABIR ABUZAR; FURTON KENNETH G; THE FLORIDA INTERNATIONAL UNIV BOARD OF TRUSTEES
摘要:The subject invention provides chemical compositions and synthesis strategies to create molecularly imprinted polymers (MIPs) via sol-gel processes. In a specific embodiment, the subject invention utilizes a(n) organic, inorganic, or metallic template analyte to create a hybrid organic-inorganic or inorganic three-dimensional network possessing cavities complementary to the shape, size, and functional orientation of the template molecule or ions. The subject invention further pertains to the use of the novel MIPs as selective solid phase extraction (SPE) sorbents for pre-concentration and clean-up of trace substances in biological and environmental samples. Synthesis of other molecularly imprinted polymers with environmental, pharmaceutical, chemical, clinical, toxicological, and national security implications can be conducted in accordance with the teachings of the subject invention.

专利号:US-2023323449-A1
优先权日:2021-12-17
标 题:Compositions and methods for detection of variants
发明人:GANTT RICHARD; ARNESON ADRIANA
权利人:TWIST BIOSCIENCE CORP
摘要:Testing the many hypotheses from genomics and systems biology experiments demands accurate and cost-effective gene and genome synthesis. Here we describe a microchip-based technology for multiplex gene synthesis. Pools of thousands of ‘construction’ oligonucleotides and tagged complementary ‘selection’ oligonucleotides are synthesized on photo-programmable microfluidic chips, released, amplified and selected by hybridization to reduce synthesis errors ninefold. A one-step polymerase assembly multiplexing reaction assembles these into multiple genes. This technology enabled us to synthesize all 21 genes that encode the proteins of the Escherichia coli 30S ribosomal subunit, and to optimize their translation efficiency in vitro through alteration of codon bias. This is a significant step towards the synthesis of ribosomes in vitro and should have utility for synthetic biology in general.

专利号:US-2024082118-A1
优先权日:2021-05-19
标 题:Topical compositions and methods of preparing the same
发明人:ABRAMOVICH SAGI; AVIDOR GAL; LANDA BENZION
权利人:LANDA LABS 2012 LTD
摘要:There is disclosed a composition comprising a water-insoluble thermoplastic compound capable of stimulating collagen synthesis (CSSC), the CSSC having a molecular weight of more than 0.6 kDa and being dispersed in a polar carrier as nano-elements having an average diameter of 200 nm or less and a viscosity of 107 mPa·s or less. The nano-elements of CSSC can be capable of stimulating the synthesis of skin proteins and/or enabling the delivery of active agents upon their application to a surface to be treated therewith. Methods for preparing the compositions and uses thereof are also provided.

专利号:US-9145304-B2
优先权日:2012-09-07
标 题 :Synthesis of nanosized sodium titanates
发明人:HOBBS DAVID T; TAYLOR-PASHOW KATHRYN M L; ELVINGTON MARK C
权利人:SAVANNAH RIVER NUCLEAR SOLUTIONS LLC
摘要:Methods directed to the synthesis and peroxide-modification of nanosized monosodium titanate are described. Methods include combination of reactants at a low concentration to a solution including a nonionic surfactant. The nanosized monosodium titanate can exhibit high selectivity for sorbing various metallic ions.

专利号:US-5662898-A
优先权日:1990-08-20
标 题 :Genes for the synthesis of antipathogenic substances
发明人:LIGON JAMES M; HILL DWIGHT STEVEN; LAM STEPHEN TING; HAMMER PHILIP E
权利人:CIBA GEIGY CORP
摘要:The present invention is directed to the production of an antipathogenic substance (APS) in a host via recombinant expression of the polypeptides needed to biologically synthesize the APS. Genes encoding polypeptides necessary to produce particular antipathogenic substances are provided, along with methods for identifying and isolating genes needed to recombinantly biosynthesize any desired APS. The cloned genes may be transformed and expressed in a desired host organisms to produce the APS according to the invention for a variety of purposes, including protecting the host from a pathogen, developing the host as a biocontrol agent, and producing large, uniform amounts of the APS.

专利号:US-9068192-B2
优先权日:2009-01-28
标 题:Compositions and methods for conversion of aldehydes to alkanes
发明人:ZENG WEIQING; HE SHENG YANG
权利人:ZENG WEIQING; HE SHENG YANG; UNIV MICHIGAN STATE
摘要:The invention provides the discovery that SCD2 (Susceptible to Coronatine-Deficient Pst DC3118-2) protein converts aldehydes to alkanes, thereby changing the composition and/or amount of synthesized waxes. The invention additionally provides homologs, orthologs and paralogs of SCD2 protein, and nucleotide sequences encoding these proteins. Also provided are expression vectors, transgenic cells, transgenic plants, transgenic seeds, methods for altering alkane production in cells, methods for identifying the function of a nucleotide sequence in the synthesis of plant surface wax, and methods for identifying plant tissue that has an altered surface wax composition. The invention's compositions and methods are useful for altering the amount and/or composition of wax produced by cells, including plants and seeds, that have been transformed with the invention's sequences.
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主要参考文献

[参考文献]: Ana-Maria Gurban, Et Al. Sensitive Detection Of Endocrine Disrupters Using Ionic Liquid--Single Walled Carbon Nanotubes Modified Screen-Printed Based Biosensors. Talanta. 2011 Sep 30;85(4):2007-13.
[参考文献]: Chih-Hsing Hung, Et Al. Modulation Of Cytokine Expression In Human Myeloid Dendritic Cells By Environmental Endocrine-Disrupting Chemicals Involves Epigenetic Regulation. Environ Health Perspect. 2010 Jan;118(1):67-72.
[参考文献]: Cynthia D Selassie, Et Al. Cellular Apoptosis And Cytotoxicity Of Phenolic Compounds: A Quantitative Structure-Activity Relationship Study. J Med Chem. 2005 Nov 17;48(23):7234-42.
[参考文献]: Ioana Cruceru, Et Al. Determination Of Three Alkylphenol Isomers In Various Water Samples Using A New Hplc Method Based On A Duet Stationary Phase. Environ Monit Assess. 2012 Oct;184(10):6061-70.
[参考文献]: L Ciofi, Et Al. Liquid Chromatographic-Tandem Mass Spectrometric Method For The Simultaneous Determination Of Alkylphenols Polyethoxylates, Alkylphenoxy Carboxylates And Alkylphenols In Wastewater And Surface-Water. J Chromatogr A. 2014 Oct 3:1362:75-88.

合成参考文献


摘要:SRI. 1989 Directory of Chemical Producers -United States of America. Menlo Park, CA: SRI International, 1989., p. 815
摘要:S109 | PARCEDC | List of 7074 potential endocrine disrupting compounds (EDCs) by PARC T4.2 | DOI:10.5281/zenodo.10944198
摘要:Panda, S. P.; Hota, S. K.; Jindal, A.; Murarka, S., Science of Synthesis: Base-Metal Catalysis, (2023) 2, 32.
参考文献:10.1002/etc.5620200905|10.1897/1551-5028(2001)020<1878:pnbdpd>2.0.co;2
摘要:Kannan K, Kober JL, Kang Y, Masunaga S, Nakanishi J, Ostaszewski A, Giesy JP. POLYCHLORINATED NAPHTHALENES, BIPHENYLS, DIBENZO-p-DIOXINS, AND DIBENZOFURANS AS WELL AS POLYCYCLIC AROMATIC HYDROCARBONS AND ALKYLPHENOLS IN SEDIMENT FROM THE DETROIT AND ROUGE RIVERS, MICHIGAN, USA. Environ Toxicol Chem. 2001;20(9):1878. doi: 10.1897/1551-5028(2001)020<1878:pnbdpd>2.0.co;2.
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