CAS: 25542-62-5; Ethyl 6-Bromohexanoate

相似化合物

4224-70-8 4286-55-9 29823-18-5

上下游产品

caprolactam ethanol 6-bromohexanoic acid 6-hydroxy-hexanoic acid ethyl esterethyl 6-fluorohexanoate 6-(4-methyl-piperazin-1-yl)-1,1-diphenyl-hexan-1-ol 6-(4-sulfamoyl-anilino)-hexanoic acid ethyl ester 6-[6-(2-benzo[1,3]dioxol-5-yl-vinyl)-5-oxo-4,5-dihydro-[1,2,4]triazin-3-ylsulfanyl]-hexanoic acid ethyl ester

6-己内酯置于氢溴酸体系中,用 乙醇 用作溶剂,以56%的收率获得6-溴己酸乙酯
参考文献:Mchintosh,John M.; Pillon,Lilianna Z.; Acquaah,Samuel O.,Canadian Journal Of Chemistry,1983,Vol. 61,P. 2016-2021
标题:Mchintosh,John M.; Pillon,Lilianna Z.; Acquaah,Samuel O.,Canadian Journal Of Chemistry,1983,Vol. 61,P. 2016-2021

专利信息

专利号:WO-9805658-A1
优先权日:1996-08-07
标 题 :Synthesis of 2-(2-furoyl)-4(5)-(2-furanyl)-1h-imidazole and analogs thereof
发明人：RHO TAIKYUN; LANKIN MICHAEL E; SHIH DAVID H; LANKIN CLAIRE M
权利人:ALTEON INC
摘要:The present invention relates to a practical and facile synthesis of 2-(2-furoyl)-4(5)-(2-furanyl)-1H-imidazole (FFI) and analogs thereof. The synthesis utilizes a novel hydrazinium salt as an intermediate reaction product which facilitates the isolation of purified product in high yields.

专利号:US-5856511-A
优先权日:1996-08-07
标题 :Synthesis of 2-(2-furoyl)-4(5)-(2-furanyl)-1H-imidazole and analogs thereof
发明人：RHO TAIKYUN; LANKIN MICHAEL E; SHIH DAVID H; LANKIN CLAIRE M
权利人:ALTEON INC
摘要:The present invention relates to a practical and facile synthesis of 2-(2-furoyl)-4(5)-(2-furanyl)-1H-imidazole (FFI) and analogs thereof. The synthesis utilized a novel hydrazinium salt as an intermediate reaction product which facilitates the isolation of purified product in high yields.

专利号:US-7893286-B2
优先权日:2007-06-01
标题 :Method for the synthesis of phospholipid ethers
发明人：PINCHUK ANATOLY; WEICHERT JAMEY P; LONGINO MARC
权利人:CELLECTAR INC
摘要:Disclosed are improved methods for the synthesis of phospholipid ether analogs and alkyl phosphocholine analogs. The methods allow greater versatility of the reactants used and greater ease in synthesizing alkyl chains of varying length while affording reaction temperatures at room temperature or below. The methods disclosed herein provide reactants and conditions using alkyl halides and organozinc reagents and do not utilize Gringard reactions thus, allowing greater ease of their separation and purity of products. The PLE compounds synthesized by the methods disclosed herein can also be used for synthesizing high specific activity phospholipid ether (PLE) analogs, for use in treatment and diagnosis of cancer.

专利号:US-11578040-B2
优先权日:2016-09-30
标题 :[5]Helicene derivatives as molecular reporters for diagnostic applications and methods of synthesis therefor
发明人：SOOKSIMUANG THANASAT; KAROONUTHAISIRI NITSARA; CHARLERMROJ RATTHAPHOL; SAHASITHIWAT SOMBOON; PANCHAN WARAPORN; MAKORNWATTANA MANLIKA; PHUENGWAS SUDTIDA; KANGKAEW LAONGDAO
权利人:NATIONAL SCIENCE AND TECH DEVELOPMENT AGENCY
摘要:The present invention provides the methods of synthesis of [5]helicene compounds and the use of the said compounds conjugating with biomolecules to work as molecular reporter for diagnostic. The compounds in the present invention have the chemical structure illustrated in the formula (1): wherein G is a connecting group composes of 2 carbon atoms selected from the group consisting of ethane and ethylene; A is a separated or connected group selected from the group consisting of cyano and imide; D1 is selected from the group consisting of oxyalkanoic acid, oxyalkanal and oxyalkanesulfonate; and D2 has structure selected from the group consisting of hydroxyl, oxyalkanoic acid, oxyalkanal, alkyl oxyalkanoate, oxyalkanol and oxyalkanesulfonate. The compounds in the present invention compose of aromatic [5]helicene core comprising long it-conjugating system. The said compounds contain functional groups which able to link with biomolecules and they are soluble in water or other solvents that used in binding process with biomolecules. Moreover, owing to having proper chemical structure, the compounds in the present invention exhibit good fluorescent emission in wavelength of 425-675 nm. When the said compounds connected with biomolecules, the biomolecules give good fluorescence and can be detected under ultraviolet radiation.

专利号:US-7408075-B1
优先权日:2005-03-23
标 题:Synthesis of phosphocholine ester derivatives and conjugates thereof
发明人：REZANKA LOUIS J
权利人:US HEALTH
摘要:Aspects of the present invention include methods of synthesizing phosphocholine analogues and the phosphocholine conjugates formed therefrom and their use in preventing infections caused by microorganisms.

专利号:US-9394354-B2
优先权日:2012-08-21
标题 :Haptens of paliperidone
发明人：HASPESLAGH PIETER RIK; VLIEGEN MAARTEN; HRYHORENKO ERIC; DECORY THOMAS R; SANKARAN BANUMATHI
权利人:JANSSEN PHARMACEUTICA NV; ORTHO CLINICAL DIAGNOSTICS INC
摘要:The invention relates to compounds of Formula I, wherein L 1 , L 2 , and L 3 are defined in the specification, useful for the synthesis of novel conjugates and immunogens derived from paliperidone. The invention also relates to conjugates of a paliperidone hapten and a protein.