CAS: 2244-16-8; (S)-2-Methyl-5-(Prop-1-En-2-yl)Cyclohex-2-Enone

相似化合物

6485-40-1 99-49-0 99-48-9

上下游产品

CAS号503-93-5 2,6,6-三甲基-2,4-环... | CAS号499-75-2 香芹酚 | CAS号74105-52-5 (S)-8-methoxy-p... | CAS号108244-69-5 carvacrol β-hyd... | CAS号7712-46-1 8-hydroxycarvot... | CAS号499-69-4 (1Alpha,2beta,5... | CAS号18457-34-6 2,2'-Dimethyl-5... | CAS号487-79-6 海藻酸(mM/ml) | CAS号99-48-9 L-香芹醇,顺反异构体混合物 | CAS号32222-06-3 骨化三醇

(-)-香芹酚置于chromium(Vi) Oxide,盐酸,Sodium Dithionite,四丁基溴化铵,水,Sodium Ethanolate,乙酸酐,碳酸氢钠,L-Proline Lithium Salt体系中,用 四氢呋喃,乙醇,二氯甲烷,水,甲苯 用作溶剂,化学反应 28.33H,反应生成右旋香芹酮
参考文献:Dauben-michno Oxidative Transposition Of Allylic Cyanohydrins-Enantiomeric Switch Of (-)-Carvone To (+)-Carvone*based On The 2010 Bader Award Lecture.
标题:Dauben-michno Oxidative Transposition Of Allylic Cyanohydrins-Enantiomeric Switch Of (-)-Carvone To (+)-Carvone*based On The 2010 Bader Award Lecture.
摘要:烯丙基氰醇在低温下经过dauben-Michno氧化反应,可以得到非常好至优异产率的β-氰基烯酮.通过将(-)-薄荷醛转化为其对映体来测试这种氧化转位作为含有潜在对称面的烯酮的对映异构体转换的潜力.
Doi:10.1139/v11-026

专利信息

专利号:US-8507562-B2
优先权日:2004-07-07
标 题 :Synthesis of (1)-beta-elemene, (-)-beta-elemenal, (-)-beta-elemenol, (-)-beta-elemene fluoride and their analogues, intermediates, and composition and uses thereof
发明人：HUANG LAN
权利人:HUANG LAN; HYWE PHARMACEUTICALS INC
摘要:The present invention provides convergent processes for preparing (−)-beta-elemene, (−)-beta-elemenal, (−)-beta-elemenol, and (−)-beta-elemene fluoride and analogues thereof. Also provided are intermediates useful for preparing (−)-beta-elemene. The present invention further provides novel compositions based on analogues of (−)-beta-elemene, (−)-beta-elemenal, (−)-beta-elemenol, (−)-beta-elemene fluoride and methods for the treatment of cancer, such as brain tumor, lung cancer, breast cancer, prostate cancer, ovarian cancer, colorectal cancer, gastric intestional cancer, and stomach cancer. n The inventors propose a combination therapy using 1) one or more of the following anti-cancer agents: including, but not limited to, Cisplatin, 5-FU, Taxol, Taxol derivatives, and any anti-cancer agent, and 2) one or more of the following (−)-beta-elemene and its analogs, including (−)-beta-elemene, (−)-beta-elemenal, (−)-beta-elemenol, (−)-beta-elemene fluoride, and their analogs, and (−)-beta-elemene's intermediate in its chemical synthesis, for the treatment of cancer, especially for the treatment of brain tumor, lung cancer, ovarian cancer, bladder cancer, cervical cancer, colon cancer, breast cancer, and prostate cancer.

专利号:US-2006014987-A1
优先权日:2003-07-07
标 题:Synthesis of beta-elemene, intermediates thereto, analogues and uses thereof
发明人：HUANG LAN
权利人:HUANG LAN
摘要:The present invention provides convergent processes for preparing beta-elemene, and analogues thereof. Also provided are analogues related to beta-elemene and intermediates useful for preparing the same. The present invention further provides novel compositions based on analogues of beta-elemene and methods for the treatment of cancer, such as brain tumor, lung cancer, colorectal cancer, gastric intestional cancer, and stomach cancer.

专利号:US-2009137828-A1
优先权日:2005-08-18
标 题 :Synthesis of 1A-Fluoro-25-Hydroxy-16-23E-Diene-26,27-Bishomo-20-Epi-Cholecalciferol
发明人：USKOKOVIC MILAN R; MARCZAK STANISLAW; LOO RALF; VAN DER SLUIS MARCEL; JANKOWSKI PAWEL; MAEHR HUBERT
权利人:BIOXELL SPA
摘要:The invention provides a method of producing 20-methyl vitamin D3 compounds of formula (I). The method includes allylic and olefin oxidation, de-carbonylation, carbonyl reduction, fluoride substitution, epoxide deoxygenation, and Wittig-type couplings.

专利号:US-11168064-B2
优先权日:2017-03-27
标 题:Synthesis of thapsigargin, nortrilobolide, and analogs thereof
发明人：EVANS P ANDREW; CHEN DEZHI
权利人:UNIV KINGSTON
摘要:The present invention relates to the preparation of compounds of Formula I, including thapsigargin, nortrilobolide and 8-O-debutanoyl-thapsigargin from commercially available (R)-(−)-carvone via synthetic intermediate compound of formula 12 by pinacol coupling and in situ lactonization.

专利号:WO-2019080686-A1
优先权日:2017-10-26
标 题:Entecavir intermediate and synthesis method thereof, and synthesis method of entecavir
发明人：JIN YEHUA; QIU FAYANG; XU HUA; WANG FANG
权利人:LAUNCH PHARMA TECH LTD
摘要:The present invention relates to a entecavir intermediate, a method of preparing the intermediate and a method for preparing entecavir using the intermediate. The methods of synthesizing entecavir and its intermediate according to the present invention have advantages in terms of controllable chirality, high yield and high product purity. In addition, the raw materials have many sources, the reagents are inexpensive and readily available, the reaction is simple, and the procedure is simple, environmentally friendly and suitable for production on an industrial scale.

专利号:WO-0007607-A1
优先权日:1998-08-04
标 题:Nutrient and therapeutic compositions for the treatment of cancer
权利人:KOSBAB JOHN V
摘要:This invention relates to nutrient and therapeutic compositions for the treatment of cancer symptoms and conditions. Compositions of this invention contain a mixture of antioxidants, components that promote collagen maintenance and synthesis, components that regulate blood lipids, glucose and/or insulin, and lower homocysteine levels. Compositions also provide supplementation for nutrient (vitamin, mineral and cofactor) deficiencies to restore and maintain normal biochemical function. Cancer formulations, particularly those adapted for treatment of female cancers, can be combined with components that provide benefit in osteoporosis.