CAS: 22047-25-2; Acetylpyrazine

相似化合物

94777-52-3 1334160-87-0 141190-61-6

上下游产品

CAS号290-37-9 吡嗪 | CAS号127-17-3 丙酮酸 | CAS号75-07-0 乙醛 | CAS号19847-12-2 2-氰基吡嗪 | CAS号917-64-6 甲基碘化镁 | CAS号75-16-1 甲基溴化镁 | CAS号61892-81-7 2-丁酰基吡嗪 | CAS号86461-64-5 1-(2-吡嗪)-3-甲基-1-丁酮 | CAS号98-96-4 吡嗪酰胺 | CAS号94777-52-3 1-(2-吡嗪基)乙醇 | CAS号19847-11-1 4-(2-吡嗪基)-2-氨基噻唑 | CAS号62124-77-0 3-(2-吡嗪基)-3-氧代丙酸乙酯 | CAS号111781-53-4 3-(二甲基氨基)-1-(2-... | CAS号132426-19-8 2-溴-1-(吡嗪-2-基)乙酮 | CAS号126353-32-0 2-溴-1-(吡嗪-2-基)乙酮氢溴酸 | CAS号179323-60-5 1-(吡嗪-2-基)乙胺 | CAS号62124-78-1 3,3-bis(methyls... | CAS号641615-37-4 N-(2-methyl-5-n... | CAS号641615-38-5 6-Methyl-N1-(4-...

吡嗪酰胺置于三氯氧磷体系中,用 乙醚 用作溶剂,化学反应 2.5H,反应生成2-乙酰基吡嗪
参考文献:5-Alkyl-2-Pyrazinecarboxamides,5-Alkyl-2-Pyrazinecarbonitriles And 5-Alkyl-2-Acetylpyrazines As Synthetic Intermediates For Antiinflammatory Agents
标题:5-Alkyl-2-Pyrazinecarboxamides,5-Alkyl-2-Pyrazinecarbonitriles And 5-Alkyl-2-Acetylpyrazines As Synthetic Intermediates For Antiinflammatory Agents
摘要:2-吡啶基腈,2-乙酰吡嗪,5-烷基-2-吡嗪羧酰胺,5-烷基-2-吡嗪腈和5-烷基-2-乙酰吡嗪被制备为合成潜在抗炎药物的中间体.将吡啶羧酰胺的自由基烷基化结果与已发表的数据进行了比较.2-乙酰吡嗪及其5-(1,1-二甲基乙基)衍生物被筛选用于生物活性,但未发现有趣的效果.
Doi:10.1135/cccc19961093

专利信息

专利号:US-9862745-B2
优先权日:2004-03-30
标题 :Synthesis of boronic ester and acid compounds
发明人：AMMOSCATO VINCE; BISHOP JOHN E; CHIU FANG-TING; GEISER ACHIM; GOMEZ JEAN-MARC; HETT ROBERT; KOELLNER CHRISTOPH; KULKARNI VITHALANAND R; LO YOUNG; MUNK STEPHEN; PICKERSGILL I FRASER
权利人:MILLENNIUM PHARM INC; MILLENNIUM PHARM INC
摘要:The invention relates to the synthesis of boronic ester and acid compounds. More particularly, the invention provides improved synthetic processes for the large-scale production of boronic ester and acid compounds, including the peptide boronic acid proteasome inhibitor bortezomib.

专利号:US-5567830-A
优先权日:1994-02-14
标题 :Process for synthesis of acetylenic carbinols
发明人：UPASANI RAVINDRA B
权利人:COCENSYS INC
摘要:A method for the preparation of an acetylenic alcohol by reaction of 1,2-dibromoethylene with an alkyl, aryl an heteroaryl lithium in an inert solvent, followed by reaction with a carbonyl-containing compound to give an acetylenic alcohol is disclosed.

专利号:US-8378099-B2
优先权日:1994-10-28
标 题:Boronic ester and acid compounds, synthesis and uses
发明人：ADAMS JULIAN; MA YU-TING; STEIN ROSS L; BAEVSKY MATTHEW; GRENIER LOUIS; PLAMONDON LOUIS
权利人:MILLENNIUM PHARMACUETICALS INC; ADAMS JULIAN; STEIN ROSS L; BAEVSKY MATTHEW; GRENIER LOUIS; PLAMONDON LOUIS
摘要:Disclosed herein is a method for reducing the rate of degradation of proteins in an animal, comprising contacting cells of the animal with certain boronic ester and acid compounds. Also disclosed herein are novel boronic ester and acid compounds, their synthesis and uses.

专利号:US-2018265546-A1
优先权日:2004-03-30
标题 :Synthesis of boronic ester and acid compounds

专利号:US-2005240047-A1
优先权日:2004-03-30
标 题:Synthesis of boronic ester and acid compounds

专利号:US-2020157143-A1
优先权日:2004-03-30
标题 :Synthesis of boronic ester and acid compounds