CAS: 4254-02-8; Cyclopentanecarbonitrile

该化合物是有机化合物,其特征是附于碳三联功能组的环球环球环球环状环,该化合物的特征是五人碳环,有助于其环形结构,而碳三联组(-CN)引入了一个极性功能组,可以进行各种化学反应.Cyclopentanecolonitricle在室内温度下一般是无色的,在黄色液体中无色,在有机溶剂中表现出适度的挥发性和溶解性.其化学特性受到硝三联组的存在的影响,该组可以参与核循环生物反应,并成为各种合成途径的前体.该化合物还可能具有中度毒性,需要在实验室环境中进行仔细处理.由于其独特的结构,环球碳三联对有机合成和材料科学,特别是制药和农用化学品的发展具有兴趣.

结构式图片

相似化合物

872-53-7 3217-94-5 3400-45-1

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上下游产品

Cyclopentyl bromide sodium cyanide cyclopentyl iodide potassium cyanidecyclopentanecarboximidic acid methyl ester hydr°Chloride cyclopentanecarboxylic acid N-[(1-Cyano-cyclopentyl)-diphenyl-methyl]-benzamide (1-Cyclopentyl-carbonyl-amino-cyclohexyl)-essigsaeure

合成工艺路线路线简述

    1-羟基环戊烷甲腈置于pd/srco3,乙醚,乙酸酐,乙酰氯体系中,化学反应生成 环戊腈
    参考文献:Ketene Acetals. Xxxiv. Tetra-And Pentamethylene Ketene Acetals
    标题:Ketene Acetals. Xxxiv. Tetra-And Pentamethylene Ketene Acetals
    摘要:
    DOI:10.1021/ja01622A040

    海关参考信息

    专利信息


    专利号:WO-2008075165-A1
    优先权日:2006-12-19
    标 题 :Novel process for the synthesis of [r-(r*, r*)]-2-(4-fluorophenyl)-beta, delta-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1h-pyrrole-1-heptanoic acid or a pharmaceutically acceptable salt thereof
    发明人:CHOPRA TIMOTHY JAY; O'NEILL PADRAIG MARY; WILKES PHILIPPA BRENDA
    权利人:PFIZER PROD INC; CHOPRA TIMOTHY JAY; O'NEILL PADRAIG MARY; WILKES PHILIPPA BRENDA
    摘要:An improved synthesis for the preparation of [R-(R*, R*)]-2-(4-fluorophenyl)- β, δ-dihydroxy-5-(1- methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1 H-pyrrole-1-heptanoic acid or a pharmaceutically acceptable salt thereof, as well as other valuable intermediates used in the process, are described. The compounds prepared by a process of the invention are useful in treating hyperlipidemia, hypercholesterolemia, osteoporosis, benign prostatic hyperplasia, or Alzheimer's disease.

    专利号:US-7399806-B2
    优先权日:2003-06-26
    标 题:Synthesis of photoresist polymers
    发明人:BENOIT DIDIER; SAFIR ADAM; CHANG HAN-TING; CHARMOT DOMINIQUE; OKAMOTO KENJI; NISHIMURA ISAO; WANG YONG
    权利人:SYMYX TECHNOLOGIES INC
    摘要:The present invention is directed to the preparation of photoresist polymers via living free radical polymerization techniques. Sterically bulky ester monomers are utilized as the polymerization components. Use of chain transfer agents is included in polymerization processing conditions. Cleavage of polymer terminal end groups that include a heteroatom are described.

    专利号:US-8475998-B2
    优先权日:2010-12-20
    标 题 :Compound synthesis method, microarray, acid-transfer composition, and biochip composition
    发明人:YUN HYOJIN; YOO CHANGEUN; KIM MYUNG-SUN; KIM SOO-KYUNG; NISHIKAWA KOUJI; GOTO HIROFUMI; MIYAMOTO HIDETOSHI
    权利人:YUN HYOJIN; YOO CHANGEUN; KIM MYUNG-SUN; KIM SOO-KYUNG; NISHIKAWA KOUJI; GOTO HIROFUMI; MIYAMOTO HIDETOSHI; SAMSUNG ELECTRONICS CO LTD; JSR CORP
    摘要:A compound synthesis method includes bonding a first compound to a substrate to form a first film. A second film is formed on the first film using an acid-transfer composition including (A) a polymer that includes a structural unit shown by a following formula (1) and a structural unit shown by a following formula (2), (B) a photoacid generator shown by a following formula (3), and (C) a sensitizer shown by a following formula (4). The second film is exposed to remove the protecting group from the first compound under an exposed area of the second film. An acid generated in the exposed area of the second film is transferred to the first film. The second film after being exposed is removed. A second compound is bonded to the first compound from which the protecting group has been removed.

    专利号:US-7238823-B2
    优先权日:2005-06-30
    标 题 :Platinum complexes with mononitrile-containing ligands
    发明人:XIAO ZEJUN; HAUSHEER FREDERICK H; PETLURU PAVANKUMAR
    权利人:BIONUMERIK PHARMACEUTICALS INC
    摘要:Disclosed herein are novel platinum-based complexes possessing one nitrile substituent group (mononitrile) covalently-bonded to the platinum, one or more nitrogen donor ligands capable of forming hydrogen bonds with the bases in DNA or RNA and leaving groups (i.e., L 1 and L 2 ) which can be hydrolyzed in vivo to active species, which can then form coordinate adducts with DNA or RNA at the Guanine or Adenine bases thereof. Also disclosed herein are the reaction schemes for the synthesis of said platinum complexes, as well as methods of treatment of various types of cancer by the administration of a pharmaceutically-effective dose of said novel platinum complexes.

    专利号:US-9937151-B2
    优先权日:2010-06-18
    标题 :Carbapenem antibacterials with gram-negative activity
    发明人:CHOI WOO-BAEG; GRUSZECKA-KOWALIK EWA; JOO HYUNG-YEUL; LIU SHUANGPEI; MAO SHULI; LI YONGFENG; KIM DEOG-IL
    权利人:FOB SYNTHESIS INC
    摘要:The present invention provides β-methyl carbapenem compounds and pharmaceutical compositions useful in the treatment of bacterial infections and methods for treating such infections using such compounds and/or compositions. The invention includes administering an effective amount of a carbapenem compound or salt and/or prodrug thereof to a host in need of such a treatment.

    专利号:US-7250475-B2
    优先权日:2003-06-26
    标 题:Synthesis of photoresist polymers
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    合成参考文献


    摘要:Kang, F.-A.; Yang, S.-M., Science of Synthesis Knowledge Updates, (2015) 2, 216.
    摘要:Bagal, D. B.; Bhanage, B. M., Science of Synthesis: Catalytic Reduction in Organic Synthesis, (2018) 2, 387.
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