专利号:US-4753985-A 优先权日:1981-10-07 标题 :Synthesis of organic compounds using deformable gel in porous rigid support 发明人:ROSEVEAR ALAN; SHEPPARD ROBERT C 权利人:ATOMIC ENERGY AUTHORITY UK 摘要:The present invention relates to the synthesis of chemical compounds and more particularly to the synthesis of organic compounds, for example, peptides and oligonucleotides. n The invention provides a composite material for use in the synthesis of organic compounds comprising a support material and, supported on the support material, an organic compound synthesizing substance. n It is preferred that the organic compound synthesizing substance is a gel (e.g. a dimethylacrylamide co-polymer gel). n The invention also provides a method for preparing a composite material for use in the synthesis of organic compounds and a method for the synthesis of organic compounds.
专利号:US-7705136-B2 优先权日:2005-02-25 标 题 :Synthesis of 3′-, or 5′-, or internal methacrylamido-modified oligonucleotides 发明人:GOLOVA JULIA B; CHERNOV BORIS K 权利人:UCHICAGO ARGONNE LLC 摘要:New modifiers were synthesized for incorporation of a methacrylic function in 3′-, 5′- and internal positions of oligonucleotides during solid phase synthesis. A modifier was used for synthesis of 5′-methacrylated oligonucleotides for preparation of microarrays by a co-polymerization method.
专利号:US-6512081-B1 优先权日:1997-07-21 标题:Synthesis of dithioester chain transfer agents and use of bis(thioacyl) disulfides or dithioesters as chain transfer agents 发明人:RIZZARDO ENZIO; THANG SAN HOA; MOAD GRAEME 权利人:E I DUPONT NEMOURS AND COMPANY; COMMW SCIENT IND RES ORG 摘要:This invention relates to the synthesis of dithiocarboxylic acid esters by reaction of bis(thioacyl) disulphides, thioacetals or vinylidane bis(thioether) with free-radicals (optionally in the presence of monomers). The invention also relates to processes for the synthesis of polymers utilising these dithioesters as polymerisation regulators (chain transfer agents) or to the use of bis(thioacyl) disulphides to generate dithioester chain transfer agents in situ.
专利号:US-3925267-A 优先权日:1972-11-06 标题 :Polymeric carrier for a controlled synthesis of peptides 发明人:COUPEK JIRI; GUT VLADIMIR 权利人:CESKOSLOVENSKA AKADEMIE VED 摘要:A new acrylic polymer suitable for use as a carrier in the controlled synthesis of polypeptides is provided. Such a polymer comprises the reaction product of (1) a hydroxyalkyl or aminoalkyl acrylate or methacrylate or an acrylanide or methacrylanide, (2) an alkylene diacrylate or dimethacrylate or an acrylate or methacrylate of a polyalcohol, a dihydroxy or polyhydroxy ether, or an alcoholic sugar or an alkylene bisacrylamide or divinylbenzene, and (3) acrylanilide or metacrylanilide or phenyl acrylate or methacrylate or a phenoxyalkyl acrylate or methacrylate or styrene, the aromatic ring being chloromethylated.
专利号:US-2024425446-A1 优先权日:2023-06-23 标题:Dichloromethane-free synthesis of cyclopropenimines 发明人:HEDRICK JAMES L; CAMPOS LUIS M; PARK NATHANIEL H; WU DINO 权利人:IBM; THE TRUSTEE OF COLUMBIA UNIV IN THE CITY OF NEW YORK 摘要:A process of forming a cyclopropenimine (CPI) is disclosed. The process includes obtaining a solution of pentachlorocyclopropane (PCC) dissolved in a first solvent and adding a secondary amine to the solution. The process further includes obtaining precipitated products, including a CPI chloride (CPI−Cl) salt and a secondary amine salt, of a reaction between the secondary amine and the PCC and mixing the precipitated products in a second solvent. The CPI−Cl salt is substantially soluble in the second solvent and the secondary amine salt is substantially insoluble in the second solvent. A CPI composition, an apparatus containing the CPI composition, a process of capturing carbon dioxide (CO2) with the CPI composition, and a process of generating carbonate with the CPI composition are also disclosed.
专利号:US-6528642-B1 优先权日:1997-08-29 标题:Mono-and di-derivatives of cyclodextrins, synthesis thereof and purification and use thereof in support 发明人:DUVAL RAPHAEL; LEVEQUE HUBERT 权利人:INST FRANCAIS DU PETROLE; CHIRALSEP SARL 摘要:Mono- and di-derivatives of cyclodextrins are completely defined, also a method for their synthesis and purification, functionalised cyclodextrins obtained from these derivatives, and the synthesis of supports comprising these cyclodextrin derivatives. Use of the supports for the preparation or separation of enantiomers, for asymmetric synthesis, for catalysis, for the preparation or separation of geometrical isomers or positional isomers, or for the preparation or separation of organic molecules with a hydrophobic nature is also described.
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合成参考文献
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