CAS: 1793-07-3; 2-(Methoxycarbonyl)Phenylisocyanate

该化合物是一种有机化合物,具有异丙胺功能组和酯组的特征,是苯并二甲酸的衍生物,其中碳酸被转化成甲基酯,一个异丁烯酸组附在芳香环上.该化合物一般是无色的,与浅黄色液体无色,有独特的气味.已知该化合物具有反应性,特别是由于异丙氰酸组,可参与各种化学反应,包括核生殖添加和聚合.甲基2-异丙胺苯并用于各种药物,农用化学品和聚合物的合成.必须谨慎处理这一化合物,因为异丁酸可能很危险,造成呼吸刺激和敏锐等风险.适当的安全措施,包括使用个人防护设备和适当的通风,在与该物质合作时至关重要.

结构式图片

欧盟法规

ECHA物质C&L通报

上下游产品

Monomethyl phthalate phosgene 2-carbomethoxyaniline 4-Nitrophenyl chloroformate methyl 2-(morpholine-4-carboxamido)benzoate 2-(2-Piperidin-1-yl-ethoxycarbonylamino)-benzoic acid methyl ester; hydr°Chloride N-2'-carbomethoxy-2-oxo-3,4,5,6-tetrahydrobenzanilide N-2'-carbomethoxy-2-morpholino-3,4,5,6-tetrahydrobenzanilide

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    专利信息


    专利号:US-7429658-B2
    优先权日:2003-09-11
    标题 :Synthesis of protected pyrrolobenzodiazepines
    发明人:HOWARD PHILIP; MASTERSON LUKE
    权利人:SPIROGEN LTD
    摘要:A method of synthesis of a N-10 protected PBD compound of formula (I): n nvia an intermediate of formula (II) or formula (V):

    专利号:US-7888505-B2
    优先权日:2006-01-13
    标 题:6,7-dihydrobenzimidazo[1,2-c]quinazolin-6-one carboxylic acids, their esters, and methods of synthesis thereof
    发明人:DOUTOVA TATYANA; LAZAREV PAVEL I; SIDORENKO ELENA N; KUZMIN VALERY S
    权利人:CRYSOPTIX KK
    摘要:The present invention relates to a 6,7-dihydrobenzimidazo[1,2-c]quinazolin-6-one carboxylic acid and its esters of the general structural formula (I), and provides a method for their synthesis (I) where R and each R′ are selected independently from the list comprising —H—CH 3 , —C 2 H 5 , —C 3 H 7 , -iso-C 3 H 7 , —CH 2 CH 2 CH 2 CH 3 , —CH(CH 3 )CH 2 CH 3 , —CH 2 CH(CH 3 )CH 3 and —C(CH 3 ) 3 ; n is 1, 2, 3 or 4; Y is a substituent selected from the list comprising —CH 3 , —C 2 H 5 , —NO 2 , —Cl, —Br, —F, —CF 3 , —CN, —OH, —OCH 3 , —OC 2 H 5 , —OCOCH 3 , —OCN, —SCN, —NH 2 , —NHCOCH 3 ; and z is 0, 1, 2, 3 or 4.

    专利号:US-6531470-B1
    优先权日:1998-01-23
    标题:Oxazolidinone combinatorial libraries, compositions and methods of preparation
    发明人:GORDEEV MIKHAIL F; LUEHR GARY W; PATEL DINESH V; NI ZHI-JIE; GORDON ERIC
    权利人:UPJOHN CO
    摘要:Oxazolidinones and methods for their synthesis are provided. Also provided are combinatorial libraries comprising oxazolidinones, and methods to prepare the libraries. Further provided are methods of making biologically active oxazolidinones as well as pharmaceutically acceptable compositions comprising the oxazolidinones. The methods of library preparation include the attachment of oxazolidinones to a solid support. The methods of compound preparation in one embodiment involve the reaction of an iminophosphorane with a carbonyl containing polymeric support.

    专利号:US-6562844-B2
    优先权日:1998-01-23
    标 题:Oxazolidinone combinatorial libraries, compositions and methods of preparation
    发明人:GORDEEV MIKHAIL F; LUEHR GARY W; PATEL DINESH V; NI ZHI-JIE; GORDON ERIC
    权利人:UPJOHN CO
    摘要:Oxazolidinones and methods for their synthesis are provided. Also provided are combinatorial libraries comprising oxazolidinones, and methods to prepare the libraries. Further provided are methods of making biologically active oxazolidinones as well as pharmaceutically acceptable compositions comprising the oxazolidinones. The methods of library preparation include the attachment of oxazolidinones to a solid support. The methods of compound preparation in one embodiment involve the reaction of an iminophosphorane with a carbonyl containing polymeric support.

    专利号:RU-2141321-C1
    优先权日:1994-03-04
    标题:Use of imidazole derivatives for preparing pharmaceutical composition showing activity to angiotensin receptors at1 and at2, some of these compounds, method of synthesis of imidazole derivatives and pharmaceutical composition based on thereof

    专利号:US-2006264622-A1
    优先权日:2003-09-11
    标题 :Synthesis of protected pyrrolobenzodiazepines
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    合成参考文献


    参考文献:10.1007/s12272-013-0091-9
    摘要:Jahng Y. Progress in the studies on tryptanthrin, an alkaloid of history. Archives of Pharmacal Research. 2013 Mar 31;36(5):517–35. doi: 10.1007/s12272-013-0091-9.
    参考文献:10.1007/s11172-023-4108-3
    摘要:Valieva MI, Rybakova SS, Kudryashova EA, Rahman M, Santra S, Kopchuk DS, Nosova EV, Gorbunov EB, Zyryanov GV, Chupakhin ON. Cyclocondensation of anthranilic acids with generated in situ methyl pyrimidine-2-carbimidate in the synthesis of 2-(pyrimidin-2-yl)quinazolin-4(3H)-ones. Russ Chem Bull. 2023 Dec;72(12):2974–8. doi: 10.1007/s11172-023-4108-3.
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