CAS: 3144-09-0; Methylsulfonamide

上下游产品

CAS号124-63-0 甲基磺酰氯 | CAS号624-90-8 Azidomethane | CAS号286459-94-7 4-But-2-ynyloxy... | CAS号362665-07-4 N-methanesulfon... | CAS号80653-53-8 N-methoxymethan... | CAS号357616-23-0 Methyl 2-[[(4-f... | CAS号74-88-4 碘甲烷 | CAS号41138-92-5 甲磺酰溴 | CAS号437652-07-8 2-丁基-5-[甲磺酰胺基]苯并呋喃 | CAS号1520-70-3 乙基磺酰胺 | CAS号918-05-8 N,N-二甲基甲磺酰胺 | CAS号202658-88-6 N-(氯乙酰基)甲基磺酰胺 | CAS号22354-11-6 N-methylsulfony... | CAS号53864-63-4 N-(methylsulfon... | CAS号22457-04-1 Methanesulfonam... | CAS号2374-61-0 N,N-二乙基甲烷磺酰胺 | CAS号23705-43-3 N-异丙基甲烷磺酰胺 | CAS号98611-90-6 N-(2-氟苯基)甲磺酰胺

二甲基砜 反应生成甲基磺酰胺
参考文献:一种新型的一锅式甲基砜转化为磺酰胺的方法
标题:一种新型的一锅式甲基砜转化为磺酰胺的方法
摘要:已经开发了由甲基砜一锅合成磺酰胺的方法.用碱和三烷基硼烷处理甲基砜得到相应的重排亚磺酸盐,其在氧化胺化后处理中转化为磺酰胺.
Doi:10.1016/0040-4039(94)85360-6

专利信息

专利号:US-5849936-A
优先权日:1995-03-15
标题:Method for the synthesis of bis-tetrahydrofuranyl annonaceous acetogenins
发明人：HOYE THOMAS R; TAN LUSHI
权利人:UNIVERISTY OF MINNESOTA
摘要:A method for the synthesis of bis-tetrahydrofranyl Annonaceous acetogenins, including the natural products and analogs thereof, is provided which proceeds by the Pd-mediated coupling of a bis-tetrahydrofuranyl-subunit comprising a terminal alkyne, with a (C4)-hydroxybutenolide subunit comprising a terminal vinyl iodide, followed by selective reduction of the resulting enyne.

专利号:US-8822702-B2
优先权日:2002-12-20
标 题 :Synthesis of amines and intermediates for the synthesis thereof
发明人：BERENS ULRICH; DOSENBACH OLIVER; SPRENGER DANIEL
权利人:BERENS ULRICH; DOSENBACH OLIVER; SPRENGER DANIEL; BASF SE
摘要:The invention relates in a first embodiment to a method for the manufacture of esters of the formula I, n nor especially of amides of the formula II,n n nwherein the symbols have the meanings given in the specification, as well as other intermediates and compounds useful in the synthesis of tryptamines and other substances mentioned in the title. The synthesis methods and intermediates are useful in the synthesis of pharmaceuticals.

专利号:US-11548898-B2
优先权日:2017-07-06
标题 :Synthesis of halichondrins
发明人：KISHI YOSHITO; AI YANRAN; YE NING; WANG QIAOYI; YAHATA KENZO; ISO Kentaro; NAINI SANTHOSH REDDY; YAMASHITA SHUJI; LEE JIHOON; OHASHI ISAO; FUKUYAMA TAKASHI
权利人:HARVARD COLLEGE; EISAI R&D MAN CO LTD
摘要:The present invention provides methods for the synthesis of ketones involving a Ni/Zr-mediated coupling reaction. The Ni/Zr-mediated ketolization reactions can be used in the synthesis of halichondrins (e.g., halichondrin A, B, C; homohalichondrin A, B, C; norhalichondrin A, B, C), and analogs thereof. Therefore, the present invention also provides synthetic methods useful for the synthesis of halichondrins, and analogs thereof. Also provided herein are compounds (i.e., intermediates) useful in the synthesis of halichondrins, and analogs thereof. In particular, the present invention provides methods and compounds useful in the synthesis of compound of Formula (H3-A).

专利号:US-2004266699-A1
优先权日:2001-10-04
标 题 :Flavonoid compounds capable of modifying the dynamic and/or physical state of biological membranes and to stimulate the endogenous synthesis of stress proteins in eukaryotic cells, relative synthesis and their use
发明人：PORTA AMALIA
摘要:The invention relates to flavonoids compounds of formula (I) and (II) capable of modifying the dynamic and/or physical state of biological membranes and to stimulate the endogenous synthesis of stress proteins in eukaryotic cells. Such compounds are molecules of plant origin or synthetic. The invention also describes a method to identify, purify and chemically synthesize such flavonoid compounds and test their efficacy through their capacity to stimulate the transcription of stress genes and as a consequence, to interact with biological membranes with alteration of their relative physical state. Such compounds and corresponding pharmaceutically acceptable derivatives and/or salts have applications in the areas of pharmaceuticals, more specifically in cosmetics and dermatology, for all those afections related to an alteration of the expression of stress genes.

专利号:US-9353057-B2
优先权日:2003-12-30
标 题:Synthesis of acyloxyalkyl carbamate prodrugs and intermediates thereof
发明人：GALLOP MARK A; DAI XUEDONG; SCHEUERMAN RANDALL A; RAILLARD STEPHEN P; MANTHATI SURESH K; YAO FENMEI; PHAN THU; LUDWIKOW MARIA; PENG GE; BHAT SEEMA
权利人:XENOPORT INC
摘要:Methods for synthesis of 1-(acyloxy)-alkyl carbamates, particularly, the synthesis of 1-(acyloxy)-alkyl carbamate prodrugs of primary or secondary amine-containing drugs are described. Also described are methods for synthesis of 1-(acyloxy)-alkyl N-hydroxysuccinimidyl carbonates which are useful intermediates in the synthesis of 1-(acyloxy)-alkyl carbamates are also described.

专利号:US-6252079-B1
优先权日:1993-06-30
标 题 :Intermediates in the synthesis of camptothecin and related compounds and synthesis thereof
发明人：CURRAN DENNIS P; BOM DAVID
权利人:UNIV PITTSBURGH
摘要:The present invention provides a short, convergent total synthesis of irinotecan and derivative compounds which comprises of a novel 4+1 radical annulation wherein the precursoris reacted with an aryl isonitrile having the formulawherein X is Br or I, and R4 is an alkyl group, an allyl group, a propargyl group or a benzyl group, and R16 is H, a C1-C6 alkoxy group, agroup wherein p is an integer between 4 and 12, or a C1-C12 acyclic dialkylamino group. The present invention also provides novel chemical intermediates for such 4+1 radical annulations.