香叶醇置于bis(Norbornadiene)Rhodium(L)Tetrafluoroborate,(Rc,Sfc,Sp)-1-[2-(1-N,N-Dimethylaminoethyl)Ferrocen-1-Yl]Phenylphosphino-1'-Dicyclohexylphosphinoferrocene,氢气体系中,用 二氯甲烷 作为反应溶剂,20.0 °C,2.53 Mpa 条件下,反应 20.0H,以99%的收率获得产物(S)-(-)-β-香茅醇 参考文献:Highly Enantioselective Hydrogenation Of 2-Substituted-2-Alkenols Catalysed By A Chenphos-rh Complex 标题:Highly Enantioselective Hydrogenation Of 2-Substituted-2-Alkenols Catalysed By A Chenphos-rh Complex 摘要:已经成功地使用chenphos-rh复合物作为催化剂,对多种2-取代-2-烯醇进行了高度的对映选择性氢化,为大多数底物提供了>=99%的对映体过量(ee).光学活性抗真菌剂阿莫洛芬首次通过氢化作为关键步骤合成. DOI:10.1039/c3Cc47727D
专利号:US-2002127598-A1 优先权日:2000-03-27 标题 :Solution-phase combinatorial library synthesis and pharmaceutically active compounds produced thereby 发明人:ZHOU WENQIANG; UPENDRAN SATHYA; IYER RADHAKRISHNAN P 摘要:The invention provides methods for solution-phase synthesis of nucleotide-based compounds and new libraries of such compounds. Compounds of the invention are useful for a variety of therapeutic applications, including treatment of viral or bacterial infections and associated diseases and disorders.
专利号:US-6620796-B1 优先权日:1999-11-08 标题:Combinatorial library synthesis and pharmaceutically active compounds produced thereby 发明人:ZHOU WENQIANG; JIN YI; ROLAND ARLENE; IYER RADHAKRISHNAN 权利人:MICROLOGIX BIOTECH INC 摘要:The invention provides new methods for synthesis of nucleotide-based compounds and new libraries of such compounds. Compounds of the invention are useful for a variety of therapeutic applications, including treatment of viral or bacterial infections and associated diseases and disorders.
专利号:EP-0995738-A1 优先权日:1998-10-19 标 题:Process for the preparation of (meth)acrylate esters and polyester (meth)acrylates 发明人:TWEEDY HARREL E 权利人:UCB SA 摘要:The present invention relates to a process for preparing acrylate esters, methacrylatenesters, polyester acrylates and/or polyester methacrylates by reacting acrylic and/ornmethacrylic acid with a monohydroxy containing compound and/or a polyhydroxyncontaining compound in a reaction vessel, in the presence of a catalyst, a polymerizationninhibitor and dense phase carbon dioxide. The dense phase carbon dioxide is in either ansub-critical, near-critical, critical or supercritical physical state. Advantages of using densenphase carbon dioxide as the solvent include the preparation of (meth)acrylate esters andnpolyester (meth)acrylates in an environmentally friendly manner by reducing or eliminatingnthe need for hydrocarbon solvents, reducing or eliminating the problems associated withnhandling hydrocarbon solvents, simplifying recovery of products, and recovery and recycle ofnreactants as compared to the conventional esterification synthesis. In addition, thenproducts produce by the process of this invention can have improved color and purity.
专利号:CN-113717910-B 优先权日:2021-07-20 标 题:A three-enzyme co-expression recombinant bacteria and its application in the synthesis of (S)-citronellol
专利号:US-5081312-A 优先权日:1988-12-21 标 题 :2,2,3,6-tetramethyl-cyclohexane-carbaldehyde 发明人:CHAPUIS CHRISTIAN; MARGOT CHRISTIAN; SCHULTE-ELTE KARL-HEINRICH; PAMINGLE HERVE 权利人:FIRMENICH & CIE 摘要:New 4,4,5,8-tetramethyl-1-oxaspiro[2,5]octane. A process for its preparation starting from 2,2,3,6-tetramethyl-1-cyclohexanone is described. n 4,4,5,8-Tetramethyl-1-oxaspiro[2,5]octane is a useful raw material for the preparation of 2,2,3,6-tetramethyl-cyclohexane-carbaldehyde, a key intermediate for the synthesis of valuable fragrance ingredients.
专利号:US-8865624-B2 优先权日:2010-09-01 标题 :Inhibitor for tobacco axillary bud growth and method for inhibiting tobacco axillary bud growth 发明人:TANAKA MOTOKI; TANAKA KEIJITSU; SHIBUYA TAKESHI; IKUTA EIJI; YOSHINAGA KOTARO; YAMAGUCHI YUKI 权利人:TANAKA MOTOKI; TANAKA KEIJITSU; SHIBUYA TAKESHI; IKUTA EIJI; YOSHINAGA KOTARO; YAMAGUCHI YUKI; SDS BIOTECH CORP 摘要:The present invention relates to an inhibitor for tobacco axillary bud growth, the inhibitor comprising, as an active ingredient, one or more kinds of very-long chain fatty acid synthesis inhibitors such as a chloroacetamide-based herbicide, fentrazamide, cafenstrole or indanofan; an inhibitor for tobacco axillary bud growth, the inhibitor comprising the aforesaid very-long chain fatty acid synthesis inhibitor together with clorthal-dimethyl or an aliphatic alcohol having 6 to 20 carbon atoms; and a method for inhibiting tobacco axillary bud growth which comprises applying the inhibitor for tobacco axillary bud growth. The inhibitor for tobacco axillary bud growth of the present invention shows sustained drug efficacy at a low concentration, induces neither chemical injury nor disease, and can contribute to the improvement in labor productivity.
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合成参考文献
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