CAS: 79-36-7; Dichloroacetyl Chloride

• ⚠️危险化学品目录(2015年版) 皮肤腐蚀/刺激,类别1A
• 英文名称Dichloroacetyl Chloride
• 中文名称二氯乙酰氯
• IUPAC名称2,2-dichloroacetyl chloride
• 其它别名2,2-Dichloroacetyl chloride; alpha,alpha-Dichloroacetyl chloride; Dichloroethanoyl chloride
• CAS编号79-36-7
• MFCD编号:MFCD00000840
• EINECS号:201-199-9
• FDA UNII编号:52O60099FY
• 分子式:C2HCl3O
• 分子量:147.39
• 产品CID: 1788192
• 产品分类化学试剂 → 有机试剂 → 酰卤

• 相似结构搜索
• 产品信息参考;;;;
• InChIKey: FBCCMZVIWNDFMO-UHFFFAOYSA-N
• InChI=1S/C2HCl3O/c3-1(4)2(5)6/h1H…
• 计算化学: 氢键受体数1.0氢键供体数0.0可旋转键数1.0

物理性质

• 熔点< 25 °C
• 沸点107.5±0.0 °C at 760 mmHg
• 闪点31.8±22.3 °C
• 密度1.6±0.1 g/cm3
• PSA:17.07
• LogP:1.27
• 折射率1.467
• 蒸汽压27.0±0.2 mmHg at 25°C
• 溶解性可溶于氯仿,己烷
• 敏感性本品刺激性强。大鼠经口LD502.46g/kg。生产车间宜通风，生产设备应密闭。操作人员穿戴防护用具，注意眼及皮肤的保护。
• 外观形态无色至淡黄色冒烟的液体
• 储存条件本品应密封保存于阴凉避光处保存。严密封保存存于棕色玻璃瓶内，外用木箱保护，防晒、防潮，贮存于阴凉、干燥环境、通风处。按刺激性物质规定贮运。
• 产品应用作为有机合成中间体,氯乙酰化剂.
• 性质描述无色有刺激性液体.沸点108-110°C,相对密度1.5315(16/4°C),折射率1.4591.能与乙醚混溶,遇水和醇会分解,在空气中会发烟.

MSDS等安全信息

• GHS象形图
• GHS符号GHS05 & GHS09;
  注释: Corrosion & Environment
• 危险类别皮肤腐蚀 类别1A
  严重眼损伤 类别1
  水生急性毒性 类别1
  致癌性 类别1B
  致癌性 类别1A
• 警示词Danger(危险)
• 危险描述H314 |造成严重皮肤灼伤和眼损伤.
  H318 |造成严重眼损伤.
  H400 |对水生生物毒性极大.
  H350 |可能致癌.
• 防范说明P202-P273-P280-P303+P361+P353-P304+P340+P310-P305+P351+P338
• UN编号1765.0
• 危险品标志C:Corrosive;N:Dangerousfortheenvironment;
• 安全声明S9-S26-S45-S61
• 危险类别码R35,R50
• WGK Germany2

欧盟法规

上下游产品

合成工艺路线路线简述

• 合成目标产物 Dichloroacetyl Chloride 主要起始原料 Trichloroethylene
• 79-01-6 = 79-36-7
  反应条件:1.1 Reagents: Oxygen,Chlorine Catalysts: Azobisisobutyronitrile,Triethylamine,Triisopropylamine; 1 Atm,85 - 106 °C
  标题:Method For Production Of Dichloroacetyl Chloride With High Conversion Rate
  参考文献:China]
  
  79-01-6 = 79-36-7
  反应条件:1.1 Reagents: Oxygen
  标题:Synthetic Method Of 2,2,2',4',5'-Pentachloroacetophenone
  作者:Huang,Jinxia; Wang,Yehao; Hu,Zili; Shi,Jiuhao
  参考文献:Huaxue Shiji 日期:1990 卷标:12(3) 页码:182-4]
  
  79-01-6 = 79-36-7
  反应条件:1.1 Reagents: Oxygen Catalysts: Azobisisobutyronitrile,Triethylamine
  标题:Preparation Of Dichloroacetyl Chloride
  参考文献:China]
  
  = 79-36-7
  反应条件:1.1 Catalysts: Aluminum Chloride,Iron Chloride (Fecl3),Cuprous Chloride
  标题:Process For Preparation Of α-Halogenated Carboxylic Acid Halides By Catalytic Oxidative Carbonylation Of Gem-Polyhalides
  参考文献:France]
  
  79-43-6 = 79-36-7
  反应条件:1.1 Reagents: Tungsten Hexachloride Solvents: Dichloromethane; 4 H,Rt
  标题:Different Outcomes In The Reactions Of Wcl6 With Carboxylic Acids
  作者:Bortoluzzi,Marco; Guarra,Federica; Marchetti,Fabio; Pampaloni,Guido; Zacchini,Stefano
  参考文献:Polyhedron 日期:2015 卷标:99 页码:141-146]
  
  79-01-6 = 79-36-7 [标题:Reaction Conditions
  标题:Detailed Chemical Kinetic Modeling Of Fuel-Rich Trichloroethane/oxygen/argon Flames
  作者:Chang,Wen Donq; Senkan,Selim M.
  参考文献:Environmental Science And Technology 日期:1989 卷标:23(4) 页码:442-50]
  
  15875-74-8 = 79-36-7 [标题:Reaction Conditions
  标题:Preparation Of Novel N-Alkylhydroxylamine Hydrochlorides
  参考文献:Federal Republic Of Germany]
  
  102099-45-6 = 79-36-7 + 79-04-9 [标题:Reaction Conditions
  标题:Synthesis And Properties Of Mixed Substituted (Chloroacetyl)Organylphenylphosphines
  作者:Lindner,Ekkehard; Merkle,Ralf Dieter; Mayer,Hermann August
  参考文献:Chemische Berichte 日期:1986 卷标:119(2) 页码:645-58]
  
  79-43-6 = 79-36-7
  反应条件:1.1 Reagents: N-Methylacetamide,Thionyl Chloride Solvents: Dichloromethane; 15 Min,-15 - -10 °C1.2 2.5 H,0 - 5 °C
  标题:New Reactive Adducts For Acyl Chloride Preparations
  作者:Cabre Castellvi,Juan; Palomo Coll,Alberto
  参考文献:Afinidad 日期:1987 卷标:44(410) 页码:333-6]
  
  79-43-6 = 79-36-7
  反应条件:1.1 Reagents: Chloroform,Oxygen Catalysts: Dimethylformamide; 3.5 H,30 °C; 2 H,30 °C
  标题:Photo-On-Demand Synthesis Of Vilsmeier Reagents With Chloroform And Their Applications To One-Pot Organic Syntheses
  作者:Liang,Fengying; Eda,Kazuo; Okazoe,Takashi; Wada,Akihiro; Mori,Nobuaki; Et Al
  参考文献:Journal Of Organic Chemistry 日期:2021 卷标:86(9) 页码:6504-6517]
  
  79-43-6 = 79-36-7
  反应条件:1.1 Reagents: Phosphorus Trichloride Catalysts: Dimethylformamide; 3.5 H,97 °C
  标题:Synthesis Of N-Dichloroacetyl-4-Ethyl-1,3-Oxazolidine
  作者:Fu,Lei; Zhou,Yuanyuan; Jia,Liwei; Zhang,Chunjing; Yu,Dan; Et Al
  参考文献:Guangdong Huagong 日期:2014 卷标:41(15)]
  
  = 79-36-7
  反应条件:1.1 Catalysts: Alumina Solvents: Benzene
  标题:A Mild And Efficient Alumina-Promoted Synthesis Of Tert-Butyl Esters
  作者:Nagasawa,Kazuo; Yoshitake,Shinji; Amiya,Takao; Ito,Keiichi
  参考文献:Synthetic Communications 日期:1990 卷标:20(13) 页码:2033-40]
  
  76-02-8 = 79-36-7
  反应条件:1.1 Reagents: Hydrogen Catalysts: Palladium Solvents: Water
  标题:The Rosenmund Reduction Of Trichloroacetyl Chloride
  作者:Sellers,J. W.; Bissinger,W. E.
  参考文献:Journal Of The American Chemical Society 日期:1954 卷标:76]
  
  79-02-7 = 79-36-7
  反应条件:1.1 Reagents: Chlorine
  标题:Chlorination Of Olefin Chlorohydrins
  作者:Spasskaya,I. F.; Etlis,V. S.; Razuvaev,G. A.
  参考文献:Zhurnal Obshchei Khimii 日期:1958 卷标:28 页码:3004-8]
  
  79-43-6 = 79-36-7
  反应条件:1.1 Reagents: Oxalyl Chloride Catalysts: Dimethylformamide Solvents: Chloroform-D; 3.5 H,Rt
  标题:Tuning The Cytotoxicity Of Ruthenium(Ii) Para-Cymene Complexes By Mono-Substitution At A Triphenylphosphine/phenoxydiphenylphosphine Ligand
  作者:Biancalana,Lorenzo; Zacchini,Stefano; Ferri,Nicola; Lupo,Maria Giovanna; Pampaloni,Guido; Et Al
  参考文献:Dalton Transactions 日期:2017 卷标:46(47) 页码:16589-16604

海关参考信息

• 2903150000-1,2-二氯乙烷
  2912110000-甲醛
  2912120000-乙醛
  2903120001-二氯甲烷
• 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
• 详情请参考：📖 海关编码查询和海关进出口税则

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