CAS: 108789-36-2; (2R,3R,4S,5S,6R)-2-((5-Bromo-4-Chloro-1H-Indol-3-yl)Oxy)-6-(Hydroxymethyl)Tetrahydro-2H-Pyran-3,4,5-Triol

该化合物是一种合成化合物,在生物化学实验中通常用作染色物基质,特别是用于检测乙型甲状腺活性.这种合成化合物具有一种不纯性,有助于其染色特性,通过色变对酶活动进行视觉检测.溴和氯分成分的存在增强了其再活动性和稳定性,使之适合分子生物学和生物化学的各种应用.它通常在有机溶剂中溶解,而且根据情况在水中表现出有限的溶解性.与许多化学物质一样,在处理该化合物时应采取安全防范措施,因为如果摄取或吸入,可能会对健康造成危害.

英文名称(2R,3R,4S,5S,6R)-2-((5-Bromo-4-Chloro-1H-Indol-3-yl)Oxy)-6-(Hydroxymethyl)Tetrahydro-2H-Pyran-3,4,5-Triol
中文名称5-溴-4-氯-3-吲哚基-D-吡喃葡糖苷
IUPAC名称(2R,3R,4S,5S,6R)-2-((5-bromo-4-chloro-1H-indol-3-yl)oxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol
其它别名5-Bromo-4-Chloro-3-Indolyl-Alpha-D-Glucopyranoside5-Bromo-4-Chloro-3-Indolyl-Alpha-D-Glucopyranoside; (2R,3R,4S,5S,6R)-2-[(5-Bromo-4-Chloro-1H-Indol-3-Yl)Oxy]-6-(Hydroxymethyl)Tetrahydropyran-3,4,5-Triol; 5-Bromo-4-Chloro-3-Indolyl-Alpha-D-Glucopyranoside; 5-Bromo-4-Chloro-3-Indolyl-Alpha-D-Glucoside; 5-Bromo-4-Chloro-3-Indoxyl-Alpha-D-Glucopyranoside; X-Alpha-D-Glc; X-Alpha-D-Glucoside; X-Alpha-Glu
CAS编号108789-36-2
MFCD编号:MFCD00155606
分子式:C14H15BrClNO6
分子量:408.63
产品CID: 124462
产品分类生物化工 → 糖类化合物 → 单糖

相似结构搜索
InChIKey: OPIFSICVWOWJMJ-HRNXZZBMSA-N
InChI=1S/C14H15BrClNO6/c15-5-1-2-6-9(10(5)16)7(3-17-6)22-14-13(21)12(20)11(19)8(4-18)23-14/h1-3,8,11-14,17-21H,4H2/t8-,11-,12+,13-,14+/m1/s1…
计算化学: 氢键受体数7.0氢键供体数5.0可旋转键数3.0

物理性质

沸点673.9 °C at 760 mmHg
闪点361.3 °C
密度1.882 g/cm3
pKa:12.74±0.70(预测)
PSA:115.17
LogP:0.7625
折射率1.731
蒸汽压4.44E-19mmHg at 25°C
外观形态白色粉末
储存条件-20°C
产品应用该化合物用于有选择性地检测婴儿母乳中CENTOBACTER SAKAZAKII 的药物-福西-异温介质基质(DFI AGAR)的基质

合成工艺路线路线简述

专利信息

专利号:WO-9721822-A2
优先权日:1995-12-12
标题 :Methods and compositions for synthesis of oligosaccharides using mutant glycosidase enzymes

专利号:EP-2398915-B1
优先权日:2009-02-20
标题:Synthesis of sequence-verified nucleic acids

专利号:US-10876110-B2
优先权日:2009-02-20
标题:Synthesis of sequence-verified nucleic acids
发明人：STAEHLER PEER F; CARAPITO RAPHAEL; STAEHLER CORD F; MATZAS MARK; LEONARD JACK T; JAEGER JOACHIM; BEIER MARKUS
权利人:CODEX DNA INC
摘要:The invention relates to methods and devices for preparing synthetic nucleic acids.

专利号:EP-0870037-A2
优先权日:1995-12-12
标题 :Methods and compositions for synthesis of oligosaccharides using mutant glycosidase enzymes

专利号:US-2017267999-A1
优先权日:2009-02-20
标题 :Synthesis of sequence-verified nucleic acids