CAS: 119683-68-0; Ferumoxides

专利信息

专利号:US-2018297857-A1
优先权日:2015-06-02
标 题:Aqueous Synthesis of Polyhedral 'Brick-Like' Iron Oxide Nanoparticles for Hyperthermia and T2 MRI Contrast Enhancement, and for Targeting Endothelial Cells for Therapeutic Delivery
发明人：HEGMANN TORSTEN; WORDEN MATTHEW; MILLER DONALD W
权利人:UNIV KENT STATE OHIO
摘要:A low temperature, aqueous synthesis of polyhedral iron oxide nanoparticles (IONPs) is presented. The modification of the co-precipitation hydrolysis method with Triton X surfactants results in the formation of crystalline polyhedral particles. The particles are herein termed iron oxide “nanobricksâ€? (IONBs), as the varieties of particles made are all variations on a simple “brick-likeâ€?, polyhedral shape such as rhombohedral shape or parallelogram as evaluated by TEM. These IONBs can be easily coated with hydrophilic silane ligands, allowing them to be dispersed in aqueous media. The dispersed particles are investigated for potential applications as hyperthermia and T 2 MRI contrast agents. The results demonstrate that the IONBs perform better than comparable spherical IONPs in both applications, and show r 2 values amongst the highest for iron oxide based materials reported in the literature.

专利号:US-2020030462-A1
优先权日:2018-07-24
标 题 :GREEN SYNTHESIS OF BIOCOMPATIBLE AND NEAR INFRARED ACTIVE EUGENATE (4-allyl-2-methoxyphenolate) CAPPED IRON OXIDE NANOPARTICLES FOR DEEP TISSUE IMAGING AND THERAPY
发明人：SHARAD GUPTA; PRASHANT KHAREY
权利人:INDIAN INSTITUTE OF TECH INDORE
摘要:NIR active, biocompatible and multifunctional (magnetic, photo-acoustic, and photo-thermal agent) E-capped iron oxide nanoparticles for deep tissue imaging and cancer therapy, are synthesized by a simple, rapid, non-toxic, low-cost and efficient completely green synthesis technique using extract made from the leaves of a medicinal aromatic plant, Pimenta dioica.

专利号:WO-2010022688-A1
优先权日:2008-08-29
标题 :Method of the synthesis of hybride nanoparticles from agglomerates of multicomponent complex metallic oxides nanoparticles
发明人：POLLERT EMIL; KAMAN ONDREJ; VEVERKA PAVEL; HERYNEK VIT
权利人:INST OF PHYSICS AS CR V V I; POLLERT EMIL; KAMAN ONDREJ; VEVERKA PAVEL; HERYNEK VIT
摘要:Hybride nanoparticles of the multicomponent complex metallic oxides are created by grains of the magnetic oxides. The grains are provided with a continuous layer of hydrated silica oxide ensuring due to the biocompatible surface their harmlessness in the organism. Utilizable in medicine for diagnostic and therapeutic applications for magnetic resonance imaging and magnetic fluid hyperthermia.

专利号:US-5228910-A
优先权日:1991-09-06
标题 :Mixed metal oxide crystalline powders and method for the synthesis thereof
发明人：JOYCE IVAN H; BLONSKI ROBERT P; MALONEY JOHN J; WELCH JOHN J; PIPOLY RICHARD A; BYRNE CHRISTINE J
权利人:FERRO CORP
摘要:A method for the synthesis of mixed metal oxide crystalline powders comprises the steps of preparing a raw material mixture containing at least two different metal cations; adding a template material to the mixture and blending it therewith; initiating formation of a mixed metal oxide by calcination of the mixture and the template material, whereby particles of the mixed metal oxides are formed; and thereafter recovering the mixed metal oxide particles. Mixed metal oxide crystalline powders comprise a template material; and metal oxides which form pigment classes of material containing the template material, the pigment classes being selected from the group consisting of borate, garnet, olivine, phenacite, phosphate, priderite, pyrochlore, sphene, spinel and zircon, as well as perovskite crystal classes of material containing the template, all of which have a uniform particle morphology and particle size ranging between about 0.2 to 100 mu with minimal comminution.

专利号:EP-0713602-B1
优先权日:1993-08-12
标 题 :Use of polysaccharide covered superparamagnetic oxide colloids
发明人：PALMACCI STEPHEN; JOSEPHSON LEE; GROMAN ERNEST V
权利人:ADVANCED MAGNETICS INC
摘要:In a method for the synthesis of a colloid including a superparamagnetic metal oxide coated with a polymer, an acidic solution of a metal salt and a polymer may be cooled, and then neutralized by the controlled addition of a cool solution of a base, and may then be converted, by the application of heat, to a homogenous superparamagnetic metal oxide colloid. According to a preferred embodiment, the polymer may be a polysaccharide. In a further embodiment of the invention, the polysaccharide may be dextran and the metal salt may be ferrous and ferric salts, which produces, according to the methods of the invention, a superparamagnetic iron oxide colloid with an extended plasma half-line.

专利号:US-7892520-B2
优先权日:2006-07-31
标 题:Solid-state synthesis of iron oxide nanoparticles
发明人：LU JUN; NG KA MING; YANG SHIHE
权利人:UNIV HONG KONG SCIENCE & TECHN
摘要:The present disclosure includes a method for preparing an aqueous dispersion of γ-Fe 2 O 3 nanoparticles. The method includes grinding an iron (II) hydrated salt, an iron (III) hydrated salt, an inorganic salt, and alkali hydroxide in a grinding or milling machine. The inorganic salt may be a salt matrix that prevents growth and aggregation of the synthesized nanoparticles. The aqueous dispersion of γ-Fe 2 O 3 nanoparticles may optionally be hydrothermally treated to become an aqueous dispersion of α-Fe 2 O 3 nanoparticles. Also disclosed is a method for preparing an mixture of α-Fe 2 O 3 nanoparticles and γ-Fe 2 O 3 nanoparticles, in which at least an iron (III) hydrated salt, an inorganic salt, and alkali hydroxide are ground in a grinding or milling machine. Uses for the nanoparticles include: a magnetic resonance image contrast agent, a color print ink, an artificial tanning pigment, a photocatalyst for degradation of organic dye, a red pigment, an adsorbent for waste water treatment, a catalyst support, and a catalyst.