CAS: 27355-22-2; 4,5,6,7-Tetrachloro-2-Benzofuran-1(3H)-One

该化合物是一种多用途有机化合物,其分子式为C8H6O2,其特点是其双环内酯结构,它是合成药品,农用化学品和香料的关键中间体.其僵硬的框架和功能性内酯组为构建复杂的分子,包括活性药物成分和植物保护剂提供了价值.Phathalide 在标准条件下表现出稳定性,并显示出与各种化学变异的相容性,例如减少和核分裂医学添加.其应用范围扩大到染料和特殊化学品的生产.该化合物的界定明确的再活性特征和合成效用强调了其在工业和研究环境中的重要性.

结构式图片

物理性质

欧盟法规

ECHA物质C&L通报REACH预注册

上下游产品

CAS号117-08-8 四氯苯二甲酸酐 | CAS号85-44-9 苯酐 | CAS号109-99-9 四氢呋喃 | CAS号60-29-7 乙醚 | CAS号64-19-7 冰醋酸

合成工艺路线路线简述

    四氯苯二甲酸酐置于锂硼氢体系中,用 四氢呋喃 用作溶剂,化学反应 0.25H,以86%的收率获得四氯苯酞
    参考文献:Narasimhan,Srinivasan,Heterocycles,1982,Vol. 18,P. 131-135
    标题:Narasimhan,Srinivasan,Heterocycles,1982,Vol. 18,P. 131-135

    海关参考信息

    专利信息


    专利号:US-7772439-B2
    优先权日:2004-10-25
    标题 :Amino or thiol linker building block for the synthesis of amino- or thiol-functionalized nucleic acids and methods of making and use thereof
    发明人:WEISS PATRICK A; WEISS VIOLETTE Y; PITSCH STEFAN
    权利人:OPERON BIOTECHNOLOGIES INC
    摘要:An amino or thiol linker building block for the synthesis of amino or thiol functionalized amino acids and generally of the following structure: n nis provided. Such building block may be introduced in the 5′ end position of an amino acid under standard coupling conditions. Such building block allows in-line coupling control, “trityl-onâ€? purification, and solid support functionalization/derivatization. Such building block is a stable, solid compound and can therefore be easily handled. With the building block of the present invention, deprotection may be carried out under standard detritylation conditions.

    专利号:US-9968097-B2
    优先权日:2012-05-30
    标题:Composition comprising a biological control agent and a fungicide selected from inhibitors of the lipid membrane synthesis, the melanine biosynthesis, the nucleic acid synthesis or the signal transduction
    发明人:WACHENDORFF-NEUMANN ULRIKE; ANDERSCH WOLFRAM; STENZEL KLAUS; SPRINGER BERND
    权利人:BAYER CROPSCIENCE AG
    摘要:The present invention relates to a composition comprising at least one biological control agent. Furthermore, the present invention relates to the use of this composition as well as a method for reducing overall damage of plants and plant parts.

    专利号:US-2007232495-A1
    优先权日:2006-03-24
    标题:Compositions and methods to add value to plant products, increasing the commercial quality, resistance to external factors and polyphenol content thereof
    发明人:NAPPA ALVARO O; LORENZINI FELIPE C; SANHUEZA ANDRES L
    权利人:NAPPA ALVARO O; LORENZINI FELIPE C; SANHUEZA ANDRES L
    摘要:The invention is related to compositions and methods that naturally protect plant tissues against ultraviolet radiation and temperature, thus giving protection against sunburn to plants, plant parts, fruits and/or flowers during their development. The invention is also related to compositions and methods to naturally improve the color of plants, plant parts, fruits and/or flowers by inducing the natural synthesis of flavonoids and anthocyanins present in plants. Likewise, the present invention is directed to improving the nutritional value of plants, plant parts, fruits and/or flowers by increasing the normal levels of polyphenolic compounds, especially flavonoids, present therein. Additionally, the present invention is related to compositions and methods that give more resistance to plants, plant parts, fruits and/or flowers against pathogens as bacteria and fungi. Finally, the present invention is related to plants, plant parts, fruits, flowers and/or propagating material treated with the compositions described in the present document.

    专利号:US-2006167240-A1
    优先权日:2004-10-25
    标 题 :Amino or thiol linker building block for the synthesis of amino- or thiol-functionalized nucleic acids and methods of making and use thereof

    专利号:US-9706777-B2
    优先权日:2012-05-30
    标题:Composition comprising a biological control agent and a fungicide selected from inhibitors of amino acid or protein biosynthesis, inhibitors of ATP production and inhibitors of the cell wall synthesis
    发明人:WACHENDORFF-NEUMANN ULRIKE; ANDERSCH WOLFRAM; STENZEL KLAUS; SPRINGER BERND
    权利人:BAYER CROPSCIENCE AG
    摘要:The present invention relates to a composition comprising at least one biological control agent. Furthermore, the present invention relates to the use of this composition as well as a method for reducing overall damage of plants and plant parts.

    专利号:TW-I491356-B
    优先权日:2010-02-23
    标题:Synthesis of 2-ethyl-3,7-dimethyl-6-(4-(trifluoromethoxy)phenoxy) quinolin-4-ylmethyl carbonate and a method for producing the same Crystallization of the pesticide composition
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    主要参考文献


    1: Asfandiarov NL, Pshenichnyuk SA, Vorob'ev AS, Nafikova EP, Lachinov AN, Kraikin VA, Modelli A. Electron attachment to the phthalide molecule. J Chem Phys. 2015 May 7;142(17):174308. doi: 10.1063/1.4919631. doi: 10.1080/10286020.2015.1054816. Epub 2015 Jun 30. doi: 10.1021/acs.jnatprod.6b00080. Epub 2016 Jul 11. doi: 10.1016/j.bmcl.2013.01.003. Epub 2013 Jan 11. doi: 10.1039/c4cp03351e. doi: 10.1021/jo500796w. Epub 2014 Jun 13. doi: 10.1186/s13020-016-0080-2. eCollection 2016.
    9: Guo H, Li ZH, Feng T, Liu JK. One new ergostane-type steroid and three new phthalide derivatives from cultures of the basidiomycete Albatrellus confluens. J Asian Nat Prod Res. 2015;17(2):107-13. doi: 10.1080/10286020.2014.951925. Epub 2014 Dec 3. doi: 10.1080/14786419.2015.1067619. Epub 2015 Aug 3. doi: 10.1038/ja.2015.85. Epub 2015 Aug 26. Chinese. doi: 10.1039/c4cc08461f. doi: 10.1002/ps.4210. Epub 2016 Jan 18. doi: 10.1590/1414-431X20132979. Epub 2013 Jul 30.
    17: Chen L, Li H, Yu F, Wang L. Ru-catalyzed decarboxylative cyclization of mandelic acids with acrylates: facile access to the phthalide skeleton. Chem Commun (Camb). 2014 Dec 7;50(94):14866-9. doi: 10.1039/c4cc06331g. doi: 10.1039/c3ob40198g. Epub 2013 Mar 5. doi: 10.1016/j.chroma.2013.01.103. Epub 2013 Feb 1. doi: 10.1016/j.bmc.2012.06.039. Epub 2012 Jun 29.

    合成参考文献


    摘要:Japan Pesticide Information., (36)(32), 1979
    摘要:Japan Pesticide Information., (40)(32), 1982
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