CAS: 40240-12-8; 1-Benzyl-1,2,3,6-Tetrahydropyridine

上下游产品

CAS号110-86-1 吡啶 | CAS号100-39-0 溴化苄 | CAS号2876-13-3 氯化-1-(苯甲基)吡啶翁 | CAS号50-00-0 甲醛 | CAS号109838-89-3 N-benzyl-(Z)-4-... | CAS号2589-31-3 Pyridinium,1-(p... | CAS号4727-72-4 N-苄基-4-羟基哌啶 | CAS号41780-52-3 3,3,5-Trimethyl... | CAS号1833-31-4 苄基二甲基氯硅烷 | CAS号100-44-7 氯化苄 | CAS号188863-87-8 4-(4-溴苯基)-1,2,3... | CAS号80477-52-7 N-苄基-1,2,3,6-四氢吡啶盐酸盐 | CAS号85838-94-4 1-B°C-1,2,3,6-四氢吡啶 | CAS号694-05-3 1,2,5,6-四氢吡啶 | CAS号66207-23-6 5,6-二氢吡啶-1(2H)-羧酸苄酯 | CAS号161157-50-2 1-B°C-3,4-环氧哌啶 | CAS号725715-12-8 3-苄基-7-噁-3-氮杂双环... | CAS号63588-62-5 1-benzyl-3,4-di... | CAS号89873-67-6 1-benzyl-3,6-di... | CAS号40240-41-3 3,6-dihydro-2H-...

1-苄基-4-哌啶甲醛置于methoxy(Cyclooctadiene)Rhodium(I) Dimer,3-甲氧基苯甲酸,4,5-双二苯基膦-9,9-二甲基氧杂蒽体系中,用 四氢呋喃 作为反应溶剂,以72%的收率获得产物1,2,3,6-四氢-1-(苯基甲基)吡啶
参考文献:Rh催化的cc键通过转移加氢甲酰化裂解
标题:Rh催化的cc键通过转移加氢甲酰化裂解
摘要:加氢甲酰化转化为逆反应 加氢甲酰化反应在化学工业中被大规模应用,通过向烯烃中加入氢气和一氧化碳来制备醛.反向过程也可以证明在修饰复杂分子以进行药物研究方面很有用,但是针对此目的的方法通常会在没有氢气的情况下去除 Co.墨菲等人.现在表明,铑催化剂可以在温和条件下实现多种化合物的选择性脱氢甲酰化(参见 Landis 的观点).该协议依赖于将 Co 和 H2 等价物有效转移到添加到混合物中的牺牲应变烯烃.科学,这个问题 P.56; 另见第.29 选择性逆转常见化学反应的催化剂为分子合成提供了多种机会.[另请参阅 Landis 的观点] 醛脱氢甲酰化反应生成烯烃的过程发生在各种甾醇(包括人体胆固醇)的生物合成过程中.在这里,我们实施了一个合成版本,其特征是甲酰基和氢化物从醛底物转移到应变的烯烃受体.铑(xantphos)(苯甲酸酯)催化剂以高化学选择性活化醛碳-氢(c-H)键以触发碳-碳(c-C)键断裂并在低负载(0
DOI:10.1126/science.1261232

专利信息

专利号:US-4895996-A
优先权日:1988-10-17
标 题 :Synthesis of alkenes from enamines via hydroboration
发明人：GORALSKI CHRISTIAN T; SINGARAM BAKTHAN; BROWN HERBERT C
权利人:PURDUE RESEARCH FOUNDATION; DOW CHEMICAL CO
摘要:Alkenes are prepared by the hydroboration of enamines followed by an elimination reaction to form the alkene. This process has wide applicability and is useful for the stereospecific synthesis of [Z] isomers. It is preferred to use 9-borabicyclo[3.3.1 nonane as the hydroborating agent and to use methanol to catalyze the elimination reaction.

专利号:US-8013157-B2
优先权日:2006-12-20
标题:Synthesis of unsaturated piperidines from piperidones with a silyl reagent
发明人：MANI NEELAKANDHA S; MORRILL CHRISTIE
权利人:JANSSEN PHARMACEUTICA NV
摘要:Syntheses of unsaturated piperidines from piperidones through a silyl piperidine reagent via the Shapiro reaction and palladium-catalyzed cross-coupling reactions with organo halides.

专利号:US-2010324292-A1
优先权日:2006-12-20
标题 :Synthesis of unsaturated piperidines from piperidones with a silyl reagent

专利号:CN-105566367-B
优先权日:2016-01-11
标 题 :A kind of synthesis N replaces the method for the borate of 1,2,5,6 tetrahydropyridine 4

专利号:CN-105503924-B
优先权日:2016-01-11
标题:A kind of synthesis N replaces the method for the borate of 1,2,3,6 tetrahydropyridine 5